HsaINT0101772 @ hg38
Intron Retention
Gene
ENSG00000145794 | MEGF10
Description
multiple EGF like domains 10 [Source:HGNC Symbol;Acc:HGNC:29634]
Coordinates
chr5:127433363-127434821:+
Coord C1 exon
chr5:127433363-127433509
Coord A exon
chr5:127433510-127434686
Coord C2 exon
chr5:127434687-127434821
Length
1177 bp
Sequences
Splice sites
5' ss Seq
GGAGTAAGT
5' ss Score
8.57
3' ss Seq
GATTTCCCTTCTGTTTTCAGTCT
3' ss Score
9.32
Exon sequences
Seq C1 exon
GTGTCCACTGTGACAGCGTGTGTGCTGAGGGACGCTGGGGCCCCAACTGCTCCCTGCCCTGCTACTGTAAAAATGGGGCTTCATGCTCCCCTGATGATGGCATCTGCGAGTGTGCACCAGGCTTCCGAGGCACCACTTGTCAGAGGA
Seq A exon
GTAAGTGTCTCATTAGGCAGTAATTTCCACCTTCCCTTCCCTGGGCACCATGTATCGAATAATGATCTCTGTCCCACCTCTCAGTTTATAGTGATGTCCTGTTGCAGTTGAAGGCAAAAGAGAGTGTAATGGTTCACTTGTCCTTTGCAGAACTGTGTTCCCTAAGAGCTTCATTCTTTCCAGCCTTCAGAACTAACCTAACAGATGGGGATTTAACCATTTCTTCTCAATAATTACTTCATTGCCTCATTGGCACAACCATCAGGATATATTTCTTCACCCTTCCTGAAAGCTTTGGAATGGTGTTCTAGAAATTCACTGACCTGTAAATATGTTATTCAGCAGTTTGGCATTGGCCTTACCTCAATTACCAGACGTCAACATCAGCCAAACCTTGAGGCAAATCATTCATCCTGCTAGTAGTCTTAAAATCAGTGCTATGGGGAAAATGGAATTGCAAAGTTGAAAAAGGAGACTGTTGACATTGGTCCTTAAGACTTCTGAGTTAGAAGATTAAGTAATCTTTTAGTAAATGCAATCAAAAAAGAATATGTAACTAATTATAAGTTATACTATTCTAATTTTTTAAATTGCCTTTCCCCCCATAAGAATTCTATGCAGTTATCATATATTTAAATCTGAATAGTATCTTGGCAAGAACTTAAGTATATAGCATTTTGGTTAATCACTTTTCGATTACAGTCATTAACCTGGACCATTTTGAGGAGGAAAAATCTTCAAATTTTGACTGTTGATCGATTTTTATTGCCAGAAACGACTCTTAAAGAATAAAGAATCAACAAATGGTTTGAGAGTACTTATTTGAGACTTATTAGTATTTCAATTTTTTTATCTCTTTATTTATTCAATGAAAATTCCTGGAGCCCTGCTTTATGCCAAGACTTGAGCTAACTGGGGCCTTAAATGGGAAAATAAAGAAGACTAAGACATTTGCTTGCTCTCAAGAAACTCAGAGTTTAGTGGCTTCTTTTCCTCATTAAAGGGTTCCTTTGTTCCTTTGTTGTTCTTGTTTTCTACTTGGAAAATTCTCCGTATCTTTTTTACTTTTTTTTAAGGTTTTGCTTTTTAACCTCTAAAACTTTAACTAGATCCCGATCTGGAATGCGAGACAAACGCATCTCAGAAGGATAACTGCTGATTTCCCTTCTGTTTTCAG
Seq C2 exon
TCTGCTCCCCTGGTTTTTATGGGCATCGCTGCAGCCAGACATGCCCACAGTGCGTTCACAGCAGCGGGCCCTGCCACCACATCACCGGCCTGTGTGACTGCTTGCCTGGCTTCACAGGCGCCCTCTGCAATGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145794:ENST00000274473:15
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF126612=hEGF=PD(23.1=6.0)
A:
NA
C2:
PF126612=hEGF=WD(100=28.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCCACTGTGACAGCGTGTG
R:
CAGAGGGCGCCTGTGAAG
Band lengths:
272-1449
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development