HsaINT0101789 @ hg38
Intron Retention
Gene
ENSG00000145794 | MEGF10
Description
multiple EGF like domains 10 [Source:HGNC Symbol;Acc:HGNC:29634]
Coordinates
chr5:127398676-127402682:+
Coord C1 exon
chr5:127398676-127398796
Coord A exon
chr5:127398797-127402545
Coord C2 exon
chr5:127402546-127402682
Length
3749 bp
Sequences
Splice sites
5' ss Seq
ATGGTAAGC
5' ss Score
9.26
3' ss Seq
CCAAGTCTCTTTGAATGCAGGGC
3' ss Score
3.5
Exon sequences
Seq C1 exon
CTGTGAGGATCTTTGTCCTCCTGGTAAACATGGTCCACAGTGTGAGCAGAGATGCCCTTGTCAAAATGGAGGAGTGTGTCATCACGTCACTGGAGAATGCTCTTGCCCTTCTGGCTGGATG
Seq A exon
GTAAGCTTCCTTCCCACCTCCTCTGCCCCTGCCCCAAAGTCACCCATTCCAGGATACTCAGTGCATACACATGCAGGAGACTTTAGCACAAAGGAAAGTTACCATGATGGTTGAAGATTCCAAAATTGGAAAGACTCAAGCCATTTTAAATCTGAAACTCTTCAGTTCTGAGGAGACAGAAGAAGGTGATTTAGTCCTAGACTTGAAGTGCATTGAAGGTTGTCATGTAAAGGGTAGTGGCCATCTGTCCTGCATTTCCCTTAAGGATAAAAAAAAGAGAGACAAATATCTAGTCTCACATGACAGTCAGTGCTGATAAACACTGGATTTATTTAACAATCATTTTCATAATTTTGTTCCATGAGTTGCTGTTGTTCTTTGGGAACATTATTCTTAACAGTGCAAGTGTCACCTGAAAAAAAATCATAGAAATCTGGGGATACATTGAGGTAAACCACATTTACCAAGTATTGCAGGACTTCTCAGAGCCTTGAGTGTGATAATCCAAGAGGAAGCTATTCAACATGTTTTCCAAATTTTGACGAGAATACCCTTTCTTCATGTAGCAATTTCACATGCTTAGAGTTATGTAGAATACACAGTGACAATTAGCTTCAAATTAGACATCTGAAATCAGGAAATATAATAATATTGATGTCATCTCTCTGAGTTGGTTTGTGCCTGTGTCTGCTTGAAGGCAGATGAGTGAGCAACCAATATCTGTTTCCTTCATTAACAAACTATTTAACAGAGCAATTGACTTTTTTATCACCTTCTATTTCCATGAGCAGTGCTAAAGCTGTTCTTTCAGAGGTTACAAGGGACTTAATTACCAAAACCCTTCTGTTCTCATTCAGCTTCATTTCTCCAAAGCTTTTCACTCTGTTGAGTACCAACCTCCCTTCCTTAATCCCTTTGCCTTCTATTTTTCTAATCATCCCGTCTCTTACCTTTCATACTAAAGATCCTTTTTCTAATCTCCCTTCTTCTGCATACTTCTTCATTACAGGATTTTGTAGGTTTAAGTCTTGTTCTTCTCTTTTCTCACCATAAATCCACTCTGGCAATCTCATCCAGACCCATAGCTTTAAGAAGTACTTGATGGTTTTTCCAGATTTTGATCTTACCTGCCTTGAGCTTAGATTTATATTTGTCACCCCAACCTTGATAACCTATAGACACAAAGCCACCGTCTCTTTGGGCAATGCCCAAGCTAGAGTCTCCACAGCCAGACCTGGTAGTAGAATTGGTCTGGTATTGCCTTTTCTTGTGGCTATGGAACAAAGGAGACCTGGAGTCCACTTTTCCATGAGGGTCTTGGGAAGTAAGAACAGTTTAAGATGTCAAGGCCACTGGGACAAGTATACAATAAAAATCAGATCTGAGAGGGTTAGAAATGGTGAGTAGCCCAGACAAAGTTCATTCTGGAGCCAAAGCATGGAGAAACAGCATGAGGCAATGGAGTTAGAGAGAGAGGAGAACTTTGAGTGCCTGAGGATGAAGACAAGGTGAAAAAGAAGCTGTTTAAGGAGTACTGAGCAGGTTTGAGTAGGCCTGGCAGAGTCAATGATAATAAATTTAATAAATCCAAACTTGTACACCCAAGCCTTTAGTAAGGCTACTCCTTCTCTACCTTTTTTGTCTTGGTTAAAACTAACACTTCTCTCTTAGTTGTCTGAGGTAAAGAAGCTGGGTTATTTCTGACTCCTCCTGTTCTTTCATTTCCTATACTCAGCCTTTTGCCAGTGTTGGTCTTTTGCAATGAAAGTATTTTGCTGGAGCAGCAGAGTGTTGAGAACTCCATGCTCTTTGGATAAGGATCTTCAGGCCTTTTACTCCTAGGACTTCTGTGTAGATATTGTCTGTGGAGTTGCCTTGCCTTGAGGCTGAAGCTCTTCTCAGTTGGGATGGTCAGGATGTGGGTTAATGGTAACCACAGGCTTGGGTTATGAGTCCCAGCACGTGGACAGATGGACCCCTCCCTAGCAGCCTAAGGGAGCCTCCTCTCACCTCTTTATCTGTGTCCCAGGCCCCTTACCTTACTTCTGCTTCAAAAATGCTTCAGTTTGTTTTTTTCTCCTGTGTAGCTGAGCTTTCAATTTATACTTCTTCTTTACAACATGTTATTTGTGCTGTCATCCTAGGTGCTTTTCAAAGATGAATATATATTCCTATAGACACACATACCTTCATATTGAAACGAAGAGAAATCATGTCCTCTTTAAAGCTGCTTGTGAATGTTAATCTTTATGCACGAAAATATTTCAGCGCATTTCTGAAGCTTATGTGGGACCATTGTGGGTAGTTAAGTCAGGCCCTGGGAGAGTGAGAATTTTCACCCCTTCTTACCACAGACTGACCTTCAGTATGTTATTCCTACAGTCATGCTTTTACCTCACATTAAGTATACCATGTCAGGCTAGAATGGAGAGACTAGAGCGATTTTTACATCCATTCCCCTCCCCACATTGTGAGCTAATTGAGGGTTGTTACCTTATCTTTGATTCTCAGTGCTTAGCTCAACACAGGCACATAGATGATTCTCAGTTAAGTGCTGATTCGAATCATCTCTCAAAGGCCTTTTCCATTCCAAGAGTCTGTGGAAGAAATTTCCCTGTTTGTAGATAGCTAGAAACCACCAGAGGAGACTTAATTAGCACACCAACTGCCTTTGTGGGTAGCCAGGAGTTAGAGGAAGTGTATTTTCTTATGCTGTCCAGAATAAACATTTAGGAAACCATCTGGTGTTCACTAGCCTCCAATTTCAGAGTGCCCACAGTCTGCCTTTTTTTAGAGAGAGGGAGGACAGAGCAACAGCTTCCAATAGTTAAAAACATTAGAAAAATCCCTGTTATTTGGGATATGTTGTTTGTCTAATTATAACTCCAATAAATAGATGAGAAGCTATGAGCCCAAGTGATACAGCCAAGTGAAGAAGAAAACAAGAGTATTTCATTGACTTATTGGTACAGTATCTTATTCCTATCCACGCAAGATTGGAGTAAATATAATGACTGTGCTTGACAAGATGGACAGCCTCTAGGGTGAGGAGAAATATCCACGTTACTCTCTTGGTTTTTCTCCCCAGGAAATAAGTTTTCCTATTGATCTTGGCTCAGCAATGCTTGTTGAATCTGCTGAAAATAAAATGTTTTTCTTCTGAAATAAATGTCTAGGTTCGTTCCTGTAGAAGTCTGTCTTCGGCAATGTGATTGTTAATTCAGGTACACAAAATTTCAATCTTGTGTTATGCTACATTTTAAGAAATAAAGCCAATGATAAAACATGTATTTTCTCTAGAACACATGGTAAAGCATTTGGATATTCCATGTGCGGCAGATGTTGCCATTTATGTAACGGATGCTCAATAAGTATTGTTGACTTATTGTGCATGTAAGACACAAGGAAGAACACTTATGAGGATTTATACATTCCTTAGGTTGCCATAATAATTTGATGTAACTTTGTTTTAAACTTCAGTTTTTAATATGGATTTTGCTTAACATTACTATTCAGCCGTCTTTGAATGTATCTTGAGATTTGGGCTTACTGAGTAATTAAGTCAATTTAATGTTTCTAATATTTTAAAGATGATGAACAGTTTATGTGCTCTAAAATTCTCTAATCTAATTTTCTTGCAGCCCTGTTCCCCATCCCTCCTTTCTATTTCCTCTCTTTTCTTCTTCATCCATCAGTTGTCTTTCCCTGGCTGGAGGCCCATCTAATTTTCCAAGTCTCTTTGAATGCAG
Seq C2 exon
GGCACAGTGTGTGGTCAGCCTTGCCCCGAGGGTCGCTTTGGAAAGAACTGTTCCCAAGAATGCCAGTGCCATAATGGAGGGACGTGTGATGCTGCCACAGGCCAATGTCATTGCAGTCCAGGATACACAGGGGAACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145794:ENST00000274473:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF126612=hEGF=PD(7.7=2.4)
A:
NA
C2:
PF079748=EGF_2=PU(93.5=63.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development