HsaINT0102194 @ hg19
Intron Retention
Gene
ENSG00000087995 | METTL2A
Description
methyltransferase like 2A [Source:HGNC Symbol;Acc:25755]
Coordinates
chr17:60517978-60522304:+
Coord C1 exon
chr17:60517978-60518117
Coord A exon
chr17:60518118-60522197
Coord C2 exon
chr17:60522198-60522304
Length
4080 bp
Sequences
Splice sites
5' ss Seq
CAAGTAAGT
5' ss Score
10.08
3' ss Seq
CATTCCCTGCTGCTCCACAGGAT
3' ss Score
8.59
Exon sequences
Seq C1 exon
ACAAATTCAGAATATGATCCTTCTCGGTGTTTTGCCTTTGTTCACGACCTGTGTGATGAAGAGAAGAGTTACCCAGTGCCCAAGGGCAGTCTTGATATTATCATTCTCATATTTGTTCTTTCAGCAATTGTTCCAGACAA
Seq A exon
GTAAGTTTGGGTCCCTTGGCTGGTAGTGTCACAAAAAGGAAGCTTTGGTGAGGGACCTTTTTTTTTAAAATAGGTTCTTGCTCTGTCAGCCCAGGCTGGAGTGCAGTGGCACGATCATGGCTCACTGCAGCCTTAACCTCTTGGGCTTAAATGATCCTCCCTCCTCAGCTTCCCAAGTAGGTGGGACCACAGGCACGTGCCACCAGTCCTGGCCAATTTTTGTGTTTTTAGCAGAGATGGGGTTTTGCCATGTTGCCCAGACTGGTCTTGAATTCCTGGGCTCAAGCGATCCTCCCACCTTGGCCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACCATGCCCAGCCTGGCGAGGGACCTTGATATTAGAGTTGGGCTCAAAGTAAAAAGAGTTTTGTTTATGTTCTGATAGACACAAAGAAGCCACACCATTTGTAGTGATGTGAGCATCTCAGCCATTTTCCTAAATTTGTCTTGATGTCCAACTTCTGTTCTGGCCTCGAAACTTCTGCAGTAGTTGGTTCTTCATTTCCTTGTTGTGGCTCAACATTGGGAAAGAATGGGAAATCAGTCTCTAATGAGTATGTGGGGAAATTCCTATTGATAGTCTCATCACATGCCGTTTTAGAACTGTGAACTGTGGGTGTCACAGCTCTTAGGTAATGTCTCATTATTGGATTTTTATTTTATTTTATTTTATTTTTTTGAGATGGAGTCTTGCCCTGTCGCCTGGGCTGGAATGCAATGGCGTGATCTAGGCTCATTGCAACCTCCACCTCCCCGGTTCACACAATTCTCCTGCCTCAACCTCCCGAGTAGCTGGGATTACAGGCACCTGCTACCATGCCCAGCTAATTTTTGTATTTTTAGTAGATGCGGGGTTTCACCATGTTGGCCAGGCTGGTCTTAAACTCCTGACCTTGTAATCTGCTTGCCTCAACCTTGCAAAATGCTGGGATTACAGGCATGAGCCACTATGCTGGCCTTTTTTTTTTTTTTGAAGACGGAGTCTTGCTCTGTTGCCCCGGCTGGGGTGCAGTGATGAGATCTTGGCTCACTGCAACCTCCACCTCCCGGGTTCAACCAATTCTCCTGCCTCAGCCTCCCAAGCAGCTGGGATTACAGGTGTACGCCACCATGCCTGGCTAATTTTTGTATTTTTTTTTTTTAGTAGAGATGGTGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCATGACCTCATGATCCGCCCGCCACGGCCTCCCAAAGTGCTGGAATTACAGGCGTGAGCCACCACGCCCAGCCTATTGGCCTTTTAAATGCTTTAAATAAAACAACCTTATTAGCAACATGAAATTTACATTGAACCTTAACTAAGGTGTTCTCTGATGCTTACAGTGTTTTAGGAAAGTGTGATACAGAATTCTATAAAATCAGATTCAGATTAAAGGAAAGTCAAATGCTATATCCTAAAATACACCATTAAAACTTCATATGCATAGGTAACCAGTGGTCCTGTGACACTACCTTCTCTTTTTTTTTTCTGAGATGGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGTGAGATTTCAGTTCACTGCAACCTCTGCCTCCAAGGTTAAAGCGATTCTCCTGCCTCAGCCTCCCGAGCAGCTGGGATTACAGACAAGCACCACCACACCTGGCTAATATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACTATGTTGGCCAGGCTGGTCTTGAACTCCTTACCTCAAGTTATCCACCCACCTCGGCATCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCAACCTGACCAAAACTACCTTCTCAAGGAAGCAGAGTCAGATGGTGGCTCAGAGATTCAGATACCATTGACTAATTCCATGGAAGCCCTTGGCACTGCCAGAGTGCAGTGAGTCTGGACAGGCTGGGGGTTGGCACATGTTAGGGTAAACTATACCCATGAAATCATGAGATTAGAGACTTCAAACATCTCCTCATTCTGTGTCATCAGAGTCCTGCAAAGGATGATTAAGTAAGTTAGTGTTAAAGGTCAAGGTAAGCTGGTGTTAGGAAGCCAGATTACATGACTAGAGACTGCAGGGACCAGTGATTGAGATCCTGGTTTATCTCCCAGAGTCCAAGGACCCCTCACTGGCTGCACAGGATAGGAGCTTTGGGTGATTGACCTTCCTCTAGAAGGCCACACTTCCTCTAGAAGGGTACTGAAGTCATCCAACCTGAGAGGATGAGTGTGAAATAAAGGCATATGCAGGATAACCCAAAAGGCCTACCATGGTTTTAAACTTTAATAATTGCAGAGGTTGACCAGGCACAGTGGCTCACGCCTATAATCCCACCACTTTGGGAGGCTGAGGTGGGAGGAGTGCTTGAAGCCAGGAGCTCAAGACCAGCTTGGGCAACAAAGCAGGACCGTTATCTCTACTAAAAATAAAAATAAAAAAATTTAGCCAGGTGCATATCTGTAGTCCCAGCTACTCAGAAGGCTGAGGCAGGAGTATGGCTTAAGCCCAGGAGTTTGAGGCTGCAGTGAAGTGAGCTACGATCACACCACTGCACTGCAGCCTGGGTGACAGAGTGAGACCCTGTCTCAAAAAAAACCTATGACCTTAGAAGTTTCAATGCTACAAACTTTTTAAAAATTGACATGGACTAAAACAAATTATTAAAATTTAAAATTCAAGCCAGACACAGTGGCACACACTTTTAGTCCCAGCTACCTAGAGACTGAGGCAGGAGGATCACTTGAGCCCAAGAGTCCAGCCGAGGCAACATAGCATAGCAGGACCCCAGCTGTTTTTTGTTTGTTTGTTTGTTTTCTGAGATGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAGTGCTATGGTCTTGGCTCACTGCAATCTCCGCCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTAGGATTACAGGTGCCTGCCACCATCCCTGGCTAATTTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCTGCCTGCCTTGGCCGTTTTTTTGTTTTTTGGTTTTTTTTAAGAGGGAAACATTCATTATGCAAAATTTAAATAGACTTTGAAATTTTTTTGGTGAAGTTTGTAGCATTTAGACTTCTGAAGTTATGAAAGCTTCAACCTGCACCAAGACTTTTGAAGAACACTGCATATGGAAAACACAGACCTAAGTGTAAAACCCTCTGTCTGTTATACTCATTTGCATACTGATTGTATTGTAAGTTCTTGAGGACAAGTCTTCATTTAACAAACAGAAAGATACAGCCCCTACATTGAAAGAGCTCAGGTCTAATGATGCAGGCAGATAAGTCACCTAGCAGAACCCACTGGATGCTCAGGATTCAGCTCAGCCACAGGCGCACAGGGCAAAGATGGCTATCTAGGACAGTGGGGAAGTGAGCCAGATAGAGAGCAGAGAACTTTTGTTTGTTTGTTTGTTTTTTGGAGACAAAGTCTCAGTTACTCTGCGGCCCAGGCCGGAGGGCAGTGGTGCAATCTTGGCTCACTGCAACCTCCACCTCCCAGGTTCCAGAAATTCTCCTGCCTCAGCCTCCTGAGTGTCTGGGATTACAGGCACACGCCACCACACCTGGCTACTTTTTGTATTTTTAGTAGAGATGGGGTTTAACCATTTTGGCCAGGCTGGTCTCAAACTCCTGACCTCATGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGTATTACAAGCATGAGCCACCGCACCCGGCCAGGAGCAGGGAACTTTCTTACGGCAGAAGCGGGCTGTCCTCGGGCCCCTTCAGGCTGAAGGCAGTGGATCGAGGCCACAGCTGTGAGCAGGCAGCTAATGTCCTTCAGTTCTAACTGAAGCAAGAGTAGAGGAGCTTAGATCTCAGACTTGGTGTGTCAGTTGAGGAAGTCCACTGGCTTTTTGGGATATGCTACAGGGAAAGAGAACCCCGTCTTTAAGGAGACCTGATTGACCGTCATTCCCTGCTGCTCCACAG
Seq C2 exon
GATGCAGAAGGCTATCAACAGGCTGAGCAGGCTTCTGAAACCTGGCGGGATGATGCTTCTGCGAGATTACGGCCGCTATGACATGGCTCAGCTTCGGTTTAAAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000087995-METTL2A:NM_181725:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF134891=Methyltransf_23=FE(23.8=100)
A:
NA
C2:
PF134891=Methyltransf_23=FE(18.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)