HsaINT0104971 @ hg19
Intron Retention
Gene
ENSG00000011028 | MRC2
Description
mannose receptor, C type 2 [Source:HGNC Symbol;Acc:16875]
Coordinates
chr17:60744118-60744894:+
Coord C1 exon
chr17:60744118-60744231
Coord A exon
chr17:60744232-60744750
Coord C2 exon
chr17:60744751-60744894
Length
519 bp
Sequences
Splice sites
5' ss Seq
GTGGTGAGG
5' ss Score
6.13
3' ss Seq
GCGCCCTGCCCTCCCCACAGACC
3' ss Score
11.16
Exon sequences
Seq C1 exon
GCCTCCTCACTGGGTACAGCTCCACCCTGTGGATCGGCTTGAATGACTTGGACACGAGCGGAGGCTGGCAGTGGTCGGACAACTCGCCCCTCAAGTACCTCAACTGGGAGAGTG
Seq A exon
GTGAGGCACAAGGTTGGGGGCGCAGGGCAGCATAGGGGCCCCGCGGGCTCTTGGCCTCCCATGGACTCCTCTCCTCATGTCCTCCTGCAGAGGGGCAGTGTGGGTAGGGGAAGCACCGACCTCCACCCCCCTCCCCAGACTGCGCCCCCCTAGCCCATGTAGGGCGGCGCTGCCCCAGGCCGAAGGTCTTGGTGCATATGGACTGGGTGCCAGCCTCCACTCACCTCTTCAGCCACCCCTGTGGGCAGCGGGCACCAGCGCACCCAGCAGCCTGGACGGGGAGGCCGGGGCGGGGCTGGTACTGGTTACTGGGTAGAAGGTTCAAGGCGACGTGCACCCAGGTTAGAAAGCGCGGAGGACCCCGTGGTCTGGGGCGGAGCTGGAGCTGAGCACCAGGCTTCCCGAACTGGCTCAGGCTTCCGAGGGAGCAGAGGGAGGTAGGAGGTTCTGAGCAGGGCCCCGGGAGCCACGGTGTGAGCTTCTCTCTCCGGGGGTGCTGGCGCCCTGCCCTCCCCACAG
Seq C2 exon
ACCAGCCGGACAACCCCAGTGAGGAGAACTGTGGAGTGATCCGCACTGAGTCCTCGGGCGGCTGGCAGAACCGTGACTGCAGCATCGCGCTGCCCTATGTGTGCAAGAAGAAGCCCAACGCCACGGCCGAGCCCACCCCTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000011028-MRC2:NM_006039:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.077 A=NA C2=0.367
Domain overlap (PFAM):
C1:
PF0005916=Lectin_C=FE(35.5=100)
A:
NA
C2:
PF0005916=Lectin_C=PD(33.6=73.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCTCCTCACTGGGTACA
R:
GTGGCGTTGGGCTTCTTCTT
Band lengths:
238-757
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)