HsaINT0106370 @ hg19
Intron Retention
Gene
ENSG00000198793 | MTOR
Description
mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]
Coordinates
chr1:11288725-11291111:-
Coord C1 exon
chr1:11290982-11291111
Coord A exon
chr1:11288976-11290981
Coord C2 exon
chr1:11288725-11288975
Length
2006 bp
Sequences
Splice sites
5' ss Seq
CCTGTAAGT
5' ss Score
7.52
3' ss Seq
TCTCTGTTGTTTTGTCCTAGCTG
3' ss Score
8.94
Exon sequences
Seq C1 exon
GCCATCCGTGTGTTAGGGCTTTTAGGGGCTTTGGATCCTTACAAGCACAAAGTGAACATTGGCATGATAGACCAGTCCCGGGATGCCTCTGCTGTCAGCCTGTCAGAATCCAAGTCAAGTCAGGATTCCT
Seq A exon
GTAAGTTGGGGGTAGCCATGAAAGACTTGCCAAGTTCTCACTCACAGAGCCCTTGCTGGTTGTGTTTAGAAAGTCTGGAGCTGGATTACTGAGAAATTATAGGATATTGGCTCGTGTAGCAACTTTTGAATGAAAAGTCAGTAGTTTCTTCTTGAATCCCGGAAGGGTTGCTGCTTCCCATTGTGGCCAGAGTCCTCATGTCTGTCTAGATTCTTTGTCAAGGGTTGGCATGCCAAGTCTGTCTGCTTTTTGATGCCAATGCAAGAGATACACATTATCACCCCATCACCTCTATCTATCTCTCATTCTTTCTTAGTGCCTCTTTGATGGTTCTCATTCCCATGGTATCTACAGAAGAAGAGGATAGAATTGATTCTTCCTGTTTTAATTGATAGGGAAATCAGAGGCGAGGCTCAGGGCCATAGGGAAAACTAGCAGCAATCAGAAATTTGGGGCTCTTTTTTCCGTGAAATGGTCTGGCCCAAGAGCTGCACTGCCTTTTTTTGTTTGTTTGTTTTTGAGATGGAGAGTCTTACTCTGTTGCCCAGGCTGGAATACAGCACTGCAACCTCTGCCTCCCGAGTTCAAGCAATTCTTCTGTCTCAGCCTCCCAGGTAACTGGGACTACAGGTGCACACCAGCACACCTGGCTAATTTTTGCATTTTTAGTAGGGAGGGGTTTTGCCATGTTGGCCTGGCTGTTCTCAAACTCCTGACCTCAAGTGATCTGCCTGCTTCAGCTTCCCAAAATGCTGGGATTACAGGCATGAGCCACTGTGCCTGGACGCCTTTTTTTTTTTTTTAAAGGTTTGTTTTATTTTTAATTGACTCAGGGAGGGGGAATAGGGAGAGGTTGGTGAATGAGTGCAAGGTTCCAGTTAGACAGGTGGAATAATTTCTGGTGGTCTGTTGCCCATTGCCTTTTATTGTTTTTATTTTAACTTAATTTTATTTTTTTGGAGACAGGGTCTCACTTTGTCACCCAGGCTGAAGTACAGTGGCATGATGTAGCCTCGACCTCCTGGGCTCAAGTGATCCTCCTGCTTCAGCCCCTCAAGTAGCTGGGACTACAGGCGTGTGCCACCACACCTCGATACTTTTTGTATAGCCCGTTGCCTTTTGACAAGTAGCCTGAGTGAATGGGGGTGGGGTATGGGGTTGCAGGAGGGTTTTCTAGACTTAACCCATATTCCCTCAGGGCAGGCCTATTTCTGACATTGAAAGTTAACATTGATTCTCCCAACTATTCCAGGAAAATATTATTACCCCAAAATAAATTGTTTCTGAACTTTCTAGATGGGATCATATTGCTTCACATTTCTTCCTCTTCTGGTATTAGAGAGGCATGCCTGTGATGTCATTCTGTCAGCCCCATAGCTGTTGAGAGCAGGGCCTGAGCCATGCTGCTCCTGGTGTTCTTCCTTATTCATGGCACCAGTCAGCCCAGCTCTTCATCTGTTTAGTTCTTACCCTCCTCGCTGCACTCTTCATGTTAGTATACCTCCCTCCCTTGCCACTGCCCCCGCTGCCACCGTCAGAGTCCTTGAGGTCCTTACTGTTCAAGTCAGGTAGGTAGTATTTGCCTACCAACTTGTCTGAATTCCCTAGGGGAACCAAGGAGCTGCTGAACAGATGTTTGCCTAATTTAATTCCCTTTACTTTATTTTGGGGGAGTAATTATTTTTATTGATGGTTTCAGTTATGAAGTTGTGAACGGTAAGAAGCTAAATTAAACAGAGCAATTTAGAGAAAACCAACCCATCATGTACTGTTTTAGGCTTTTGTGGTTTGAGTAATAGAAAAGCCAAAAACCGTTTACTCCTTGATGGTGAGAGGCTATTCATTGGTTCCTAATAGACCTTGAACTCCCAACAGTGTTAGAACATACTAGGAAGAAAGATATGAATGCTAATGTCTGTTAGGAGGTTGTTTGTTACTAACCATGCTCTGCCTGAAGTCACGTCATGCCATGTGTAGCTCTAACACTCTCTGTTGTTTTGTCCTAG
Seq C2 exon
CTGACTATAGCACTAGTGAAATGCTGGTCAACATGGGAAACTTGCCTCTGGATGAGTTCTACCCAGCTGTGTCCATGGTGGCCCTGATGCGGATCTTCCGAGACCAGTCACTCTCTCATCATCACACCATGGTTGTCCAGGCCATCACCTTCATCTTCAAGTCCCTGGGACTCAAATGTGTGCAGTTCCTGCCCCAGGTCATGCCCACGTTCCTTAACGTCATTCGAGTCTGTGATGGGGCCATCCGGGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198793-MTOR:NM_004958:18
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.045 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF118653=DUF3385=FE(25.1=100)
A:
NA
C2:
PF118653=DUF3385=FE(48.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)