MmuINT0102044 @ mm10
Intron Retention
Gene
ENSMUSG00000028991 | Mtor
Description
mechanistic target of rapamycin (serine/threonine kinase) [Source:MGI Symbol;Acc:MGI:1928394]
Coordinates
chr4:148470572-148472164:+
Coord C1 exon
chr4:148470572-148470701
Coord A exon
chr4:148470702-148471913
Coord C2 exon
chr4:148471914-148472164
Length
1212 bp
Sequences
Splice sites
5' ss Seq
CCTGTAAGT
5' ss Score
7.52
3' ss Seq
TCTCTGTCACCTTGTCCTAGCTG
3' ss Score
6.99
Exon sequences
Seq C1 exon
GCTATCCGAGTGTTGGGGCTCCTTGGGGCTTTGGATCCCTACAAGCACAAAGTGAACATCGGCATGATCGACCAGTCCCGGGACGCTTCCGCTGTCAGCCTGTCAGAGTCCAAGTCAAGTCAGGATTCCT
Seq A exon
GTAAGTTAGGACTCACGTCCTCCTGTCCATGGTAGGAACAACCTTGGTCAGGGAACTGATAGGTACTGAATCTCTTGGCAACTTGTGAATGAAGAGCCTGTAGTCCCTGCGTCTAACCAGTCCTGTCTCTGCCCAGGGTCTTTGTCAGGGTTAACAGGCTAAGTCTGGGTTACTTTTGACCGCTGTCGTCTGTGTCGTCTTTTGTTAGTGCTTCTTTTTTTTTTTTTTCTTCTTCTTTTATTCCTGGGCCCTCATGAAGGGGGAGGATAGCTCTTGTTTTCTCTGTTTCATTTGAATGAAATCAGGACATAGAAAGACCAGTAGCCCCACAAGACCTGGGCCCCTTCTTTTTGCATCTAGTCTGACAATAGAGACCCATTGCCTTTTGACAAGGACCCGAGCGTTTGGGAACGAGGGTAGAATATGAGTTTCTAGCCCACCATCTACTGGGGAAAGCCTGTTGATGAAATTGAAGGTTCAACAATGGTCTCCTCAATGCTGTAGCAGAATATGATTTTACAACAATGAAACTGTTTGTTCCCTATAAGCTCTTTAGGCTGGTTGTTTGGTTTTCTCCATTTATTTCCTTCTCCCATCTGGGGTAAGGGAGTGTACTGTGTGGCTCCCCTTTGCTCCCTGACCGTGAAGAGCAGAGCCCAGGCCAGTTACTCGTGTTCCTCAGCAGCGCCTGACGTCCTGTCTCTCATCCCCTGCATCTCACCTCCTCACTGCATGGCACCATGGCCAGGACAGAGTCCTTGCTGTTCAGGGTATGGCATATGCCTGCTAACATGTCTGTAGTCCCTGTGGGACTAGCCATCTGTGCAACAGATGTTTGCCTAATTTACTTCCCTTTCCTTTCATTTGGAGGAGTAGTTATTTTTATTGATGGTTCCAGCTCTGAGGTTGTGAACTGTGACGCTGAGAAGCTACGTTAAACCTAGGAATTTAGAGAAAACCCATCATGCACTGTTTCAGGCTTTGGTGCTTTGGGTAGTAGAAAAGCTCGGATGAGCTCTGCTCCTGACAGGGGAGCCTATTCACCGCTTCCTAATAGCCCTGCGCTCGGCGTTCACAGCACTGTCAGAACATGCAGGAGAACACATGCATGCTGAGGCCTCTGAAGGGGCTTTGTTTGCTACTAGCCATGCTTTGCCTCACATCGGAGGCCCGCCACCAATACTTACGACTCTCTCTGTCACCTTGTCCTAG
Seq C2 exon
CTGACTACAGCACCAGTGAAATGCTGGTCAACATGGGAAACCTGCCCCTGGACGAGTTCTACCCCGCTGTGTCCATGGTGGCCTTGATGCGGATCTTCCGAGATCAATCCCTCTCTCACCACCACACCATGGTGGTGCAGGCCATCACCTTCATCTTCAAGTCCCTGGGGCTCAAGTGTGTGCAGTTCCTGCCCCAGGTCATGCCCACATTCCTTAATGTCATCCGAGTCTGTGATGGGGCCATCCGGGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000028991:ENSMUST00000103221:18
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.057 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF118653=DUF3385=FE(25.1=100)
A:
NA
C2:
PF118653=DUF3385=FE(48.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGCTTTGGATCCCTACAAGC
R:
CCCCATCACAGACTCGGATGA
Band lengths:
345-1557
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types