HsaINT0107438 @ hg19
Intron Retention
Gene
ENSG00000109061 | MYH1
Description
myosin, heavy chain 1, skeletal muscle, adult [Source:HGNC Symbol;Acc:7567]
Coordinates
chr17:10403943-10404816:-
Coord C1 exon
chr17:10404427-10404816
Coord A exon
chr17:10404070-10404426
Coord C2 exon
chr17:10403943-10404069
Length
357 bp
Sequences
Splice sites
5' ss Seq
AAGGTACAA
5' ss Score
6.82
3' ss Seq
CTACCACTTTTTGAATGCAGGGA
3' ss Score
6.16
Exon sequences
Seq C1 exon
GCCCGCATTGAGGAGCTGGAGGAGGAAATCGAGGCAGAGCGGGCCTCCCGGGCCAAAGCAGAGAAGCAGCGCTCTGATCTCTCCCGGGAGCTGGAGGAGATCAGCGAGAGGCTGGAAGAAGCCGGTGGGGCCACCTCAGCCCAGATTGAGATGAACAAGAAGCGGGAGGCTGAGTTCCAGAAAATGCGCAGGGACCTGGAGGAGGCCACCCTACAGCATGAAGCCACGGCGGCCACCCTGAGGAAGAAGCATGCAGATAGTGTGGCCGAGCTTGGGGAGCAGATTGACAACCTGCAGCGAGTGAAGCAGAAGCTGGAGAAGGAGAAGAGTGAGATGAAGATGGAGATCGATGACCTTGCTAGTAACATGGAGACTGTCTCCAAAGCCAAG
Seq A exon
GTACAATCAACACTTCACATTGATTATTTGGTTTTTTGTTTTTCCCTTTAGCACAAATATGATTTGTATCTCAAAAACGTCTCATGAACTAAATCAGGCACCCTTTTTCTCATATCACGTATAGTACAACTTAGTAAAGTAGTTAGATTAACAAGTAATTCAGTGGCTGTATGCTTGGACTATGTATCTTATTAGTCTTTCCATTCACTATCTAAGACCTTTGCTGGTTTTGTTTGTAAAGATAGTTTCTTCTCAAAATAAATGAGTACTGCAGCTCATATGGAATGTTTAGATTACTGAAACTTTCTTTGGTCCAACTACTTACTTGAGATGCCTTCTACCACTTTTTGAATGCAG
Seq C2 exon
GGAAACCTTGAAAAGATGTGCCGCGCTCTAGAAGATCAACTGAGTGAAATTAAGACCAAGGAAGAGGAGCAGCAGCGGCTGATCAATGACCTCACAGCACAGAGAGCGCGCCTGCAAACAGAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109061-MYH1:NM_005963:27
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.923 A=NA C2=0.767
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(15.0=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(4.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGCAGCGCTCTGATCTCTC
R:
TAGAGCGCGGCACATCTTTTC
Band lengths:
358-715
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)