HsaINT0107444 @ hg38
Intron Retention
Gene
ENSG00000109061 | MYH1
Description
myosin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:7567]
Coordinates
chr17:10497069-10497452:-
Coord C1 exon
chr17:10497287-10497452
Coord A exon
chr17:10497194-10497286
Coord C2 exon
chr17:10497069-10497193
Length
93 bp
Sequences
Splice sites
5' ss Seq
AACGTGAGA
5' ss Score
5.13
3' ss Seq
TATTTTTTGTTCACCAACAGAGG
3' ss Score
7.64
Exon sequences
Seq C1 exon
ATCCTGGCAGAATGGAAACAGAAGTGTGAAGAAACTCATGCTGAACTTGAAGCTTCTCAAAAGGAATCCCGCTCACTCAGCACAGAACTATTTAAGATTAAGAATGCTTATGAGGAATCTTTAGACCAACTTGAAACCTTGAAACGGGAAAATAAGAATTTGCAAC
Seq A exon
GTGAGAACATTTTACCTTTTCTTTAACAATAAAAGATTTGAAAGAATCTTTTCCAACTATAAACAAATTTCTATATTTTTTGTTCACCAACAG
Seq C2 exon
AGGAGATTTCTGATCTCACTGAACAGATTGCAGAAGGAGGAAAGCGCATCCATGAACTGGAAAAAATAAAGAAGCAAGTTGAGCAAGAAAAGTCTGAACTTCAGGCTGCCTTAGAGGAGGCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109061:ENST00000226207:32
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.357 A=NA C2=0.452
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(6.4=100),PF045827=Reo_sigmaC=FE(38.5=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(4.8=100),PF045827=Reo_sigmaC=PD(24.5=83.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTTCTCAAAAGGAATCCCGC
R:
TTCATGGATGCGCTTTCCTCC
Band lengths:
171-264
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development