HsaINT0107451 @ hg19
Intron Retention
Gene
ENSG00000109061 | MYH1
Description
myosin, heavy chain 1, skeletal muscle, adult [Source:HGNC Symbol;Acc:7567]
Coordinates
chr17:10395627-10397766:-
Coord C1 exon
chr17:10397671-10397766
Coord A exon
chr17:10395886-10397670
Coord C2 exon
chr17:10395627-10395885
Length
1785 bp
Sequences
Splice sites
5' ss Seq
GCGGTGAGT
5' ss Score
10.49
3' ss Seq
AAATGGATTTCCATTCACAGGAG
3' ss Score
6.17
Exon sequences
Seq C1 exon
ACTGAGGAAGACCGCAAGAATATTCTCAGGCTCCAGGACCTGGTGGACAAACTGCAAGCAAAGGTGAAATCCTACAAGAGACAAGCTGAAGAAGCG
Seq A exon
GTGAGTTCACAACCCCTTGGGGTGATTTTTCTCAGACATGACCAGGCCAGTTTAGTTAAAGTGACAAAAGAAAAGATGAGTAAAATGAGGAAGGATCAAAAGAAAACAAATGGCTACATGGAGGTCCAAGGCTGAGGTAAAACCAACCACCTGACAAGCCAGCAGAAGATGTTCTAGAGATGGGGAAGAGCAAATGCAAAGCTTTTGAGTGGGAAAGAGTCTGGCTCAAGAAGCAGACAAAAAAAGGAGGAAAGCACCACAACTGGGACTGGAGAGCCAGGCAGGAGGCAGCTCATAGGGTCTTCCAGGCCATGGTAAGAACAATAAGGTACTGGGAAGCCAGGGAGGGTTTTAATGTGGGTCAGTCACTACCTGATCTATATTTTTTAAAAAGAGCATTTGGGATACTATGTAAAGAATCGGTTACTGGGTAACACAAGTGGGTGCAGAGAGACATGTTAGGAAGCTTTTCAGGTCGGTTCTGTGGCTTGGATAAGAGAGTGGAGCAGAGAGAAGTGGAGAAATTCAGGACATATTTTGGAGGTAGAAACTACAAGATTGCTAATAGGTTGCACTTGGGAGATGAAAGAAAGGCAATTAAGAGTAATTTATCAAGTTTATGGTTTGAGTAACCAAGTGGATGATGTAACACTTAAGTGGGGAACAAAGGGAAGAACAGAATTGCAGGGCAAGAAAGAAACAGGAATTCTGTTTTAGATACATAATACCATATATACACAAGTGAACATGTCAAGTAAATAGTTAAATATAAGATTCTGAAACTCAGAAGGTCTTGGTTATGTTCAAATCAGTAGATTCTTAACACTCCACTTTATCTCATTTCCGTATCCCATGATTCATCTGGATTAATAATCAAATAGTTTCAACTTCCTACATATAAATATTCATAGTTACATATCACAAATGAGTTCCTCTGTTCATTGATGGTTTTTATTTTACCCCTGACATCTAAGGTAAGAGAGAGAGAAAGATGGGAATGGAGGGGAATGAGGGAGGGAGAGAAAACAAACACACTTGTGTGCACGGACACACACACACGCTACTGTCCATACCTCGGACAAATTGCTTAATCTTTCTCCAGTTCCTACTTTCCTCATCTGTAAGAGGAAAAGCTGAGGTTTTTTCTCAAGCTATACTATTTAATGATTCTAAGCTTTATGTCTGTTCTAAATTTGAATGCCACATTTTGGAGGTTCTTACTGAGACTTTTAAATAAGAATGATTACCAGAGACTAAACTAGAACTGACCTGCTCAAATTCTCTGCTATATATTTAAGTATAATCAGAGACAGCTCAGACTATTTTAGGAAACAAACTTCTTGCTTAATTTCTAAACTTAAGTGGCAATAATTTATACTCACATGGCAATAACTTATATTCAAGCTTAATGGTTTGGTTTGGTATAGATTGCATACTTGCACTCTTAAAAGGTTTGGTTCCATTCTCAGGATTCTGAAAAAAACAAACAAACAAACAAAAAAAAAAACAAAGCTGGACACCTGGCATATTTAGTAGTAGCTCTAGGATGTTCTGCTGTTCTAAAAGTTCAGATACAAAGGTCACCTGTCCTTCCTTGTTATCTATGAGTTCAAGAAGCTAATGCAAAAATAAAAAAAAATAAAAATTCAAGAGCATTTCTCTAGGTTTCTTAAAATATCTGCTAGAGTGAATCATTTTTAAGTAAAAAGGAAATTCAAGATCCACTGACCTAAGAATGGAAAAATTCTGAACTTTCTTCCCTCATAAATGGATTTCCATTCACAG
Seq C2 exon
GAGGAACAATCCAACGTCAACCTCTCCAAATTCCGCAGGATCCAGCACGAGCTGGAGGAGGCCGAGGAACGGGCTGACATTGCTGAGTCCCAGGTCAACAAGCTGAGGGTGAAGAGCAGGGAGGTTCACACAAAAATCATAAGTGAAGAGTAATTTATCTAACTGCTGAAAGGTGACCAAAGAAATGCACAAAATGTGAAAATCTTTGTCACTCCATTTTGTACTTATGACTTTTGGAGATAAAAAATTTATCTGCCAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109061-MYH1:NM_005963:39
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.250 A=NA C2=0.240
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(3.6=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=PD(4.7=78.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTGAGGAAGACCGCAAGAAT
R:
TCCAAAAGTCATAAGTACAAAATGGA
Band lengths:
334-2119
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)