HsaINT0107483 @ hg19
Intron Retention
Gene
ENSG00000133026 | MYH10
Description
myosin, heavy chain 10, non-muscle [Source:HGNC Symbol;Acc:7568]
Coordinates
chr17:8393658-8395827:-
Coord C1 exon
chr17:8395615-8395827
Coord A exon
chr17:8393871-8395614
Coord C2 exon
chr17:8393658-8393870
Length
1744 bp
Sequences
Splice sites
5' ss Seq
AACGTAAGT
5' ss Score
10.74
3' ss Seq
CTGATGCTTCGGTGGTTTAGGTT
3' ss Score
6.93
Exon sequences
Seq C1 exon
CTGTTAGCAGAAGAGAAGAGCATCTCTGCTCGCTATGCCGAAGAGCGGGACCGGGCCGAAGCCGAGGCCAGAGAGAAAGAAACCAAAGCCCTGTCACTGGCCCGGGCCCTCGAGGAAGCCCTGGAGGCCAAGGAGGAGTTTGAGAGGCAGAACAAGCAGCTCCGAGCAGACATGGAAGACCTCATGAGCTCCAAAGATGATGTGGGAAAAAAC
Seq A exon
GTAAGTCGCCTGGTGGGCTCCACACTTCCGCACGGGAGAGTATCCCAGGGGCCTGGGCCTTCACACAGGAGCGGGCGACTCCTCAGGGGAGCCTGAAGGACCTGGGAATGCACAGCCCAGCAGCAAAGCCATCTAGGAGTGTTTTGGCCTGTGCATGCGTACGGGGTTCAGGTCTTCTGGGACTGCTGTGAGGTTTTCTGCAGTCTTCCCCCAGCACTGGCTGGAGGTGAACATGTTTCTTCTTGTCCTTTCACTGCCCTCCCTGCTCCAGCCTGCATCCTGGCAGGAGGGCCTTTCAACAAAAGGTTTCATGGTTCTGCCGTCACAGGTAGTTATCAAACATGAGGTGAGTGGGGACCTGGAGAGGAGGAGGAGGGAATGGCAGCTCCCTCTGACCTGGTTCTTCCCAGGGAGGCCCCACTGTTTTCTTTGAGAGCTTCAGTAGCTTTGGGGGCTTATCCACAGCTTGGAAGCTTCTGTGGCACAGTTTTTCTTTCCATTGCATACATCTTCCACAAGAGCTGCCATGATATTTATTTACCCTACGTCTCTCCCTTAGTGTATGACGTGTTGAAGATAGCAAAACAAACCCAGGCCTGGTATCAAAGGCAAGGTTCCCTGGCTCCTCCACAGGCTTCCATTCTGACCATGGGAAGCCACTTAAGCTTTTGAAGCCTAAGTTTCCTTATCTGCCAGATGGACATTATACTTGCCCAATTTCATGAAGTTACTGCATCTGCTTTGAAAAGCACACAAAGTCCTCTAAAAAGGCAGGATCTCATTTTCATGTGCTATGGGCCATCTGGCCACATCATAAGTCAGCGAAGGTGGTCCCACCTTTCTGCTGGGTCTCCTACAACTTGGCGCCCAGGGACTAGCCCCATGGACAAAAAGAGGCCACTGAAAGTAGAAGTGGCCATGGTTACACAGTGAAATGTGGAGAGAGAACTCTACAGTTGATTTCATGTTCGTTTTCTGTAGCATCAACACTCACATGTTGATCCCACAAACAGGTCTTTTGTGCCTACTGAGCACCAGACACTGTAGAAATGGACCTTCCTCCTGTCCTAGGATTCCCCGCGCCTGTCCCCGTGAGAACTGCAGTGGTCCTGGACCCCAGAGGGGGTGCACAGCAGCACCAAGGCCTCCCTCCAAAGGCTGCTGTGAGGGTCAAAGGGCACAGGAGGTGGAGCTCTCAGCACAGTGCTTGGCGCAGAGAATGAGGGAAATGGTGCTGGGGGCATCTTTGTCCAGAGAAAGATCAAGGCCTGTGTACTGTGCCCTGCTTCTTAGGCCCAAGCCACCCTAATAATCAGCAGTTTCCACATGTGCTTTTCAATACGAATGATCTTCTCTACAGCAAGAAGAGATGTACTGTTGTACTTGTTCCTCACAGACAGCAGGCAAGGAGTCAGTCAACAGACAGGTTCCCTGACATGGCTGTTTCCTTTGTTCTTTGGCTCACTGAAGAGCTCTCAGCTTAAAGGTCATCAGAGGAGGATGACCAGAGAACACGTGGGAATAAAGACATCCGCACTGTAGTTCTGAACTGCATACACTGAAATGGAGAATAGCAGCAGCTTTCAGGGGAGAGGGAAGGATGTGTATGCATGTGGCAGGGGGCCGGCCCAGGGGGACCAAAGTGGCCAGCATGCCACGAGTGGGCCTGTAAAACAGTAAGACTGCTGTTCTTCATATGTGCCTCCACCCCGGTCAACTCTTTCCTGATGCTTCGGTGGTTTAG
Seq C2 exon
GTTCACGAACTTGAAAAATCCAAACGGGCCCTAGAGCAGCAGGTGGAGGAAATGAGGACCCAGCTGGAGGAGCTGGAAGACGAACTCCAGGCCACGGAAGATGCCAAGCTTCGTCTGGAGGTCAACATGCAGGCCATGAAGGCGCAGTTCGAGAGAGACCTGCAAACCAGGGATGAGCAGAATGAAGAGAAGAAGCGGCTGCTGATCAAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133026-MYH10:NM_005964:32
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.761 A=NA C2=0.718
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(8.2=100),PF115593=ADIP=PU(36.9=57.7)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(8.2=100),PF115593=ADIP=PD(61.3=95.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGAGGCCAGAGAGAAAGAAACC
R:
GCAGCCGCTTCTTCTCTTCAT
Band lengths:
353-2097
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)