HsaINT0107483 @ hg38
Intron Retention
Gene
ENSG00000133026 | MYH10
Description
myosin heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:7568]
Coordinates
chr17:8490340-8492509:-
Coord C1 exon
chr17:8492297-8492509
Coord A exon
chr17:8490553-8492296
Coord C2 exon
chr17:8490340-8490552
Length
1744 bp
Sequences
Splice sites
5' ss Seq
AACGTAAGT
5' ss Score
10.74
3' ss Seq
CTGATGCTTCGGTGGTTTAGGTT
3' ss Score
6.93
Exon sequences
Seq C1 exon
CTGTTAGCAGAAGAGAAGAGCATCTCTGCTCGCTATGCCGAAGAGCGGGACCGGGCCGAAGCCGAGGCCAGAGAGAAAGAAACCAAAGCCCTGTCACTGGCCCGGGCCCTCGAGGAAGCCCTGGAGGCCAAGGAGGAGTTTGAGAGGCAGAACAAGCAGCTCCGAGCAGACATGGAAGACCTCATGAGCTCCAAAGATGATGTGGGAAAAAAC
Seq A exon
GTAAGTCGCCTGGTGGGCTCCACACTTCCGCACGGGAGAGTATCCCAGGGGCCTGGGCCTTCACACAGGAGCGGGCGACTCCTCAGGGGAGCCTGAAGGACCTGGGAATGCACAGCCCAGCAGCAAAGCCATCTAGGAGTGTTTTGGCCTGTGCATGCGTACGGGGTTCAGGTCTTCTGGGACTGCTGTGAGGTTTTCTGCAGTCTTCCCCCAGCACTGGCTGGAGGTGAACATGTTTCTTCTTGTCCTTTCACTGCCCTCCCTGCTCCAGCCTGCATCCTGGCAGGAGGGCCTTTCAACAAAAGGTTTCATGGTTCTGCCGTCACAGGTAGTTATCAAACATGAGGTGAGTGGGGACCTGGAGAGGAGGAGGAGGGAATGGCAGCTCCCTCTGACCTGGTTCTTCCCAGGGAGGCCCCACTGTTTTCTTTGAGAGCTTCAGTAGCTTTGGGGGCTTATCCACAGCTTGGAAGCTTCTGTGGCACAGTTTTTCTTTCCATTGCATACATCTTCCACAAGAGCTGCCATGATATTTATTTACCCTACGTCTCTCCCTTAGTGTATGACGTGTTGAAGATAGCAAAACAAACCCAGGCCTGGTATCAAAGGCAAGGTTCCCTGGCTCCTCCACAGGCTTCCATTCTGACCATGGGAAGCCACTTAAGCTTTTGAAGCCTAAGTTTCCTTATCTGCCAGATGGACATTATACTTGCCCAATTTCATGAAGTTACTGCATCTGCTTTGAAAAGCACACAAAGTCCTCTAAAAAGGCAGGATCTCATTTTCATGTGCTATGGGCCATCTGGCCACATCATAAGTCAGCGAAGGTGGTCCCACCTTTCTGCTGGGTCTCCTACAACTTGGCGCCCAGGGACTAGCCCCATGGACAAAAAGAGGCCACTGAAAGTAGAAGTGGCCATGGTTACACAGTGAAATGTGGAGAGAGAACTCTACAGTTGATTTCATGTTCGTTTTCTGTAGCATCAACACTCACATGTTGATCCCACAAACAGGTCTTTTGTGCCTACTGAGCACCAGACACTGTAGAAATGGACCTTCCTCCTGTCCTAGGATTCCCCGCGCCTGTCCCCGTGAGAACTGCAGTGGTCCTGGACCCCAGAGGGGGTGCACAGCAGCACCAAGGCCTCCCTCCAAAGGCTGCTGTGAGGGTCAAAGGGCACAGGAGGTGGAGCTCTCAGCACAGTGCTTGGCGCAGAGAATGAGGGAAATGGTGCTGGGGGCATCTTTGTCCAGAGAAAGATCAAGGCCTGTGTACTGTGCCCTGCTTCTTAGGCCCAAGCCACCCTAATAATCAGCAGTTTCCACATGTGCTTTTCAATACGAATGATCTTCTCTACAGCAAGAAGAGATGTACTGTTGTACTTGTTCCTCACAGACAGCAGGCAAGGAGTCAGTCAACAGACAGGTTCCCTGACATGGCTGTTTCCTTTGTTCTTTGGCTCACTGAAGAGCTCTCAGCTTAAAGGTCATCAGAGGAGGATGACCAGAGAACACGTGGGAATAAAGACATCCGCACTGTAGTTCTGAACTGCATACACTGAAATGGAGAATAGCAGCAGCTTTCAGGGGAGAGGGAAGGATGTGTATGCATGTGGCAGGGGGCCGGCCCAGGGGGACCAAAGTGGCCAGCATGCCACGAGTGGGCCTGTAAAACAGTAAGACTGCTGTTCTTCATATGTGCCTCCACCCCGGTCAACTCTTTCCTGATGCTTCGGTGGTTTAG
Seq C2 exon
GTTCACGAACTTGAAAAATCCAAACGGGCCCTAGAGCAGCAGGTGGAGGAAATGAGGACCCAGCTGGAGGAGCTGGAAGACGAACTCCAGGCCACGGAAGATGCCAAGCTTCGTCTGGAGGTCAACATGCAGGCCATGAAGGCGCAGTTCGAGAGAGACCTGCAAACCAGGGATGAGCAGAATGAAGAGAAGAAGCGGCTGCTGATCAAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133026:ENST00000269243:32
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.761 A=NA C2=0.721
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(12.0=100),PF115593=ADIP=PU(37.3=57.7)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(12.0=100),PF115593=ADIP=PD(60.9=94.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGAGGCCAGAGAGAAAGAAACC
R:
GCAGCCGCTTCTTCTCTTCAT
Band lengths:
353-2097
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development