HsaINT0107497 @ hg19
Intron Retention
Gene
ENSG00000133026 | MYH10
Description
myosin, heavy chain 10, non-muscle [Source:HGNC Symbol;Acc:7568]
Coordinates
chr17:8451631-8452105:-
Coord C1 exon
chr17:8451962-8452105
Coord A exon
chr17:8451727-8451961
Coord C2 exon
chr17:8451631-8451726
Length
235 bp
Sequences
Splice sites
5' ss Seq
TGTGTATGT
5' ss Score
3.3
3' ss Seq
TTCTTTTTATCAATATGAAGCAA
3' ss Score
3.16
Exon sequences
Seq C1 exon
CTGATTTGCTTCTTGAAGGATTTAATAACTACAGGTTTCTCTCCAATGGCTATATTCCTATTCCGGGACAGCAAGACAAAGATAATTTCCAGGAGACCATGGAAGCAATGCACATAATGGGCTTCTCCCATGAAGAGATTCTGT
Seq A exon
GTATGTGTGATTTCTCTAAGATTCTGGTACTCACTTTCCTAAGACTTATACATCTGGGGTAAATCACCTAAACTAGAAAATGACTGGGAAACTAATGAATTGTATGAAATCCTGAAAAGACATGTCTTACTGAAAAGTTTTGTATAGCTAATTTTTAGCACAAAATAAATGAGAATATGTCTCCGCTACATTTTGAGGCAATATTAATTTTTTTTTTCTTTTTATCAATATGAAG
Seq C2 exon
CAATGCTTAAAGTAGTATCTTCAGTGCTACAGTTTGGAAATATTTCTTTCAAAAAGGAGAGAAATACTGATCAAGCTTCCATGCCAGAAAATACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133026-MYH10:NM_005964:9
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.020 A=NA C2=0.182
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(7.0=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(4.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTACAGGTTTCTCTCCAATGGC
R:
CTGTATTTTCTGGCATGGAAGCT
Band lengths:
213-448
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)