HsaINT0107516 @ hg38
Intron Retention
Gene
ENSG00000133392 | MYH11
Description
myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569]
Coordinates
chr16:15735366-15737620:-
Coord C1 exon
chr16:15737449-15737620
Coord A exon
chr16:15735579-15737448
Coord C2 exon
chr16:15735366-15735578
Length
1870 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGCG
5' ss Score
7.38
3' ss Seq
GCTGGGTCTCTCCCTGGAAGGCT
3' ss Score
4.12
Exon sequences
Seq C1 exon
TGCGGCTAAAGAAGGAAGAGAAGAGCCGACAGGAGCTGGAGAAGCTGAAACGGAAGCTGGAGGGTGATGCCAGCGACTTCCACGAGCAGATCGCTGACCTCCAGGCGCAGATCGCAGAGCTCAAGATGCAGCTGGCCAAGAAGGAGGAGGAGCTGCAGGCGGCCCTGGCCAG
Seq A exon
GTAGCGGGGCTGGCAAGGGGCATTTGCTGTGTGTCCATGTATCCCCTGGGCCCCTGCTCATTCGCTCATTCGCAGTGGCTGTCTTGGTCAAGGCGGCCCCAGGCCCTTGGCATGAACTTCGTTTCCCAGGCCAGGCCTCCCACAAGCCTTCTCGACCCTGTTCACTCCCCCAGATCCTCACCTTCGACTTTCTTCTCTTCCCTGCAAACACATCATGTCTTTGCAGTTGATCTCACCTACTCCCATGGTGTTGCTGCTGCCTCTTCGACATCCAGGCTTTTCTCATCTAGACCCCCTTCTGAATTTCCGATTGCCCAATGAGTCAATTTCCACCGTCATCTCAAACACCCCTGTCTAAGGCGGGAATGACCTTCCTTTCCCCAGCCCCTCCCTCTAAGGGCCCTCTTTTTTGTGAACACCAATCTCCTCCTTTGTTTCTGCCGACCCACAGCAAGCAGCAACCTTCAGATTCTGCCAGTCCTTCTAAATGTCCCCCACCCATTTCCTCTGGTTTTTCCCTCTTCCTGGCTCTTAGCTGGATTTACACTAATGCTAATACTGCAGCAGCCACTATGAATGATTATTTACCTGCTCACTCGGTGCTAAGTTCTTTTCAAGCAATACCTTTGCAGACACCTGGCCAGGTGTACTGCCGGTGTCTTTGAGGAGGAAGCTGAGCCTCCTAGGGGTAACGCAACAGGAGCAATGTCATTGCTTCTAAGAGGCAGAGCTGGGATTTAAGCCTCAAAGCTTTCTGATTGATCCCCTGGCCTGGCTCTTTTGTCGGCCAATTTGTGCTATGTTGACAGTGCTACGGTGATGAAGGGAAAGCATCTCTCTGGGGCAGGAACCTGCTCACAAAACTTTGCTGGCTGGATGCAGTGGCTCACGCCTGTAATCTCAGCACTTTGGGAAGCCGAGGTGGGGGGATTGCTTGAGGCCAGCAGTTTGAGACCAACATGGGCAACATAGCAAGACCCTGTCCCTACAAAAAGTTAAAAAATGAGCCAGGCATGGTGGTGTGTGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGATGGGAGGATCACTTGAGCCCAGGAGGTTGAGGCTAAAGTGAGCTATGATCATGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACCCTGTCTCAAAACAATAATAACAACAAAACAAAAACCTAACTTCACTGGCTTACTAGGGAAAATCCAGTTTCCTTAGCCTCACCCTCAGAGCCCATCCACCCTCTGCAGTCTCACCCCAACCCAACTATTTCACTTTCTCTCTTGTTGCTGCCCTTTCACAAGTACAGTAAAATCAAAGTGCTTGCCTCTCCTGCAGCATTCTGCCATTTAACAGGGCTTCTTGCAGCCCACCTTGATCTCTGGTCACCACCTCCACCAGATGCAGAGCCCCAGTCTGAATATCCCCCGCAAGCAGTGGCTGGCCAAATGCTGTGCATGGGGCGGGTACTCAGTCACTGAGCAAATGCAGAAAGAACAGACAGTTGCCAGGGAAGAAGAACTGTCCAACATTCAGAAAGCATCTACACAGTCCCTACTGTGACCAGGTACCTTGCCAGTCTGGGGTCAATGCTTTGCATTCTTGCACACACATGCACACACGTGCATACACACGTACACACACCCATGCACATGTACAACCTGTTTTGATGTCAGACCTTGGCACTCACATCCTATGTTAATCTCATATAGTCTGGCATGTCAAGAAGCAGACCTGGGGACATGGATAGAAGGTGTTTGATGTCTCTGCAACATAACTGTCTGGTCCCAGAAAAGTTTTTGGCCACATTGTAAGAGAGGAAACCAAGGGACCTGGGGGTTCATTCTGCTGGGTCTCTCCCTGGAAG
Seq C2 exon
GCTTGACGATGAAATCGCTCAGAAGAACAATGCCCTGAAGAAGATCCGGGAGCTGGAGGGCCACATCTCAGACCTCCAGGAGGACCTGGACTCAGAGCGGGCCGCCAGGAACAAGGCTGAAAAGCAGAAGCGAGACCTCGGCGAGGAGCTGGAGGCCCTAAAGACAGAGCTGGAAGACACACTGGACAGCACAGCCACTCAGCAGGAGCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133392:ENST00000300036:25
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.293 A=NA C2=0.806
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=PD(29.9=75.9),PF0003816=Filament=FE(22.2=100),PF0157614=Myosin_tail_1=PU(2.9=43.1)
A:
NA
C2:
PF0003816=Filament=FE(27.6=100),PF0157614=Myosin_tail_1=FE(8.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAAGAGAAGAGCCGACAGGA
R:
CTGTCCAGTGTGTCTTCCAGC
Band lengths:
348-2218
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development