HsaINT0107518 @ hg19
Intron Retention
Gene
ENSG00000133392 | MYH11
Description
myosin, heavy chain 11, smooth muscle [Source:HGNC Symbol;Acc:7569]
Coordinates
chr16:15820705-15826565:-
Coord C1 exon
chr16:15826421-15826565
Coord A exon
chr16:15820912-15826420
Coord C2 exon
chr16:15820705-15820911
Length
5509 bp
Sequences
Splice sites
5' ss Seq
AGGGTAATG
5' ss Score
5.98
3' ss Seq
CCCTCTGCTTCCTTCGCCAGGCC
3' ss Score
10.1
Exon sequences
Seq C1 exon
GGCCAAGAGGGAGCAGGAGGTGACGGTGCTGAAGAAGGCCCTGGATGAAGAGACGCGGTCCCATGAGGCTCAGGTCCAGGAGATGAGGCAGAAACACGCACAGGCGGTGGAGGAGCTCACAGAGCAGCTTGAGCAGTTCAAGAGG
Seq A exon
GTAATGCTTTTTGGTGATGCTTTTTGGTGATGACACATAAGAGTGACATCAGCAGCCTCAAATTACTACAGGTCAGGGTCTGCATAAAGACAAAAAACAAGTTACATAAGATTCTAATGATGATGATAGCAGCTTATATTTATTTACAAAATGCTTCCCATACAGGCTGGGTGAGGTGGCTCACGCCTGTAATCCCAGTACTTGGGGAGGCTGAGGCGGGAGGATCGCTTGAGCTCAGGAGTTGGAGACCAGCCTGGGCAACATAGTGAGACCTTGTTTCTACTAAAATTTTAAAAAAGTAGGCCAGGCGTGGTGGCTCAAGCCTGTAATCCCAGCACTTTGGGAGGCCAAACTGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCGAAACCCTATCTCTACTACAAATACAAAAAATTAGCCGGGCGCGGTGGTGCATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATCATGCCATTGCACTCCAGCCTGAGCAACAGAGCAGGATTCCATCTCAAAAAAATAAAATAAAATAAAATATTGGCCAGGCCTGGTAGTGCATTCCTGTGGTCCCAGCTATTTGGGAGGCTGAGGTGGGAGGATCGTTTGAGCCTGGGAGGTTGAGGCTGCAGTGAGCCCTGTCATGCCACTGCACTCTAGCCTGGACGACACAGTGAGACCTTAATCAAACAATAAAAATAGGCTGGGCACGGTGGCTCACCATGTCTGTAATCCCAGCAATTTGGGAGGCAAGGCGGGCAAATCACTTGAGCTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACCAAAAATATAAAGAATTAGCTGGGTGTGGTGGCATGTGCCTGTAATCTTAGCTACTCGGGAGGCTGAGGCAGGACAATCACTTGGACCCAGGAGGAAGAGGTTGCAGTGAGCTCAGATCGTGCTACTGCACTCCAGTCTGGGCGACAGAGTGAGCCGCCATCTCAAAAAAAGAAAAAAAAAAAAGAATGAATAGAAATGCTTCTCATACAGTATGTCAATTAATCTTCACAACCACCCTGTGAGACGTGTACTATTAAACTCATTTTACAAGCAAAGAAACTGAGGTCCTAGGTGCCTAGAGGTGAAGAGACTTACCCAAGGTCACACTGCTGGTAAGTGACAGAGCCATGATTTGCACCCAAACAGTCTGGTCCTAGACCCCACTTTCTGGCCTCTACAGGACTGAAGGCCTATAGGATGGGTGGGGCCTATCAATATACTGCCCTTCAGGGATAAGCAAAGGTGTAACAACACTTTCGGGGAGATTTAAATGAAACTTAAAACTGGGATCATTCTATCCACTTTAATTTCTCTGCAGACTGGAGGAAGGCCAGGCATGGCGGCTCATGCCTCCCGTAATCCTAACACTTTGGGAGGCCAAGGAGGGAGGATTGCTTGAGCCCAGGACTTTCAGATCGCCTGGGCAACATAGCGATTTTTCTTTTGTAAAAAAAAAAAAGACTGGAGGAAACTTGTCATTATTTGATTTCAATGGCAGAACAGCTCTCTCCGGCATAATTTGAGAATGACTAGGTCAAATCACTCTCCCGTTGTTGGAACTCTTTGCGGTGTATGGGAGTGGGAGCTGGTAAATAGCAGTACCGAATGCTGAATCTTGGGTGCTCTTCTCTCCTTTGGGGTAGTGCCTGTGCTTCATTCCCCAGGGTAAGTTTTTTAGCTTGCGACCTTCGGCCAGATTGTTTTCCTGAAAGCCTGAGTTACATTACCCTCAGCGTTGCAGCTCCTCCACATCCCCTTCAGTGGAAGCTTTTGGTTCTGCTAGATTAAGTGGGTGCAGCATTGCCTAAAAATTTTGGGGAATTTGCATTTGGTTCTATCACTAGTGTATTGGTCCGTTGTTGCACTGCTCTACAGAAATACCCAAGATTGGATTATTTGTTTATTTTTTGAGCAGTGGAGTCTTACTCTGTCACTCAGGCTGGAGTTCAGTGGCGTGATCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAAATGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACACACCACCATGCCCGGCTAATTTTTTTTTTTTTTTTTTTTTTTAGTAGAGATGGGGTTTTGCCATGTTGGCCAGGCTGATCTCGAACTCCTGACCTCAGGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGAGATGACAGGTGTGAGCCACTGCACCACCCTGAGATTGGGTAATTTCTAAAGAAGAGAGGTTTAATTGGCTCACGGTTCTGCAGGCTGTACAGAAAGCATAGCAGCTTCTGCTTCTGGGGAGGCCTCAGGAAACTTACCATCATGGTGGAAGGCAACGGGGAGGCAGGCATGTTTTACATGACCAGAGCAGGCAGAAGAGAGAGAATGGGGAGCTGCCAGACACTTTTAAACAACCAGATCTCATGAGGGCAGCACCAAAGGGATAGTGCTAAACCATTAGAAACTGCCCCCAAAGGCCGGGCGCGGTGGCTCATGCTTATAATCCCAGCACTTTGGGAGGCTGAGATAGGCGGATCACCAAGTCAGGAGTTCAAGACTAGCCTGACCAACATAGTGAAACCCCATCTCTACTAAAAATACATAAAATTAGGCTGGGTGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGCCCGAGGCAGGCAGATCACCTGAGGTCAGGAGTTTGAGACCAGTCTGGCCAACATGGCAAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGACGTGGTGGCGGTCGCCTGTAATCCCAGCTACTTGGGAGGCTGAGACATGAAAATCACTTGAACCCAGGAGGTAAAGGTTGCAGTGAGCCAAGATTGTGCCACTGCACCCCAGCCTGGGCAACAGAGTGAGACTCAGTTTCAAAAAAAAAAAAAAAAAATTATGGTTGGAAGAGTGAGGCCCCAGACAGAATCACTGACCCTCCCCATGCTTGGGGTTCATTAGACGTGAACAGGAGCTAGAAGCCAAGCCCATTCCCAGCCAGGCCTCTTTGGGAAGACGCAGTTATTAAGACCACCAGCAGACGGCATGTCCATTACTGACCCGCACAAAGCAGGTAGAGGTGCAAACCTCTGCCCATCTCAGGTGCAGGGAAACAGAGGCCTTTGCCTCTAACAACTTGAATTCTGATGTAGAGACCTGGTTCCATCTGCTTGTGGGGGAAACGTTTAACATCAGCTCCTACCTGGGCTCCCCAGGCCCTCGTGCGGTTTGGCCCCAGTTCTGGGGTCTTAGGCTGGGCTAAGGTTTCTGGGAGCCCATGTCCCCTAGGGTCCCCGCTTCACTGCTTTGTTACCACCAAGAGACTCCCTGTCCCCATCTGAGGTCTGGCAGCTCTTAGTCATGTCTTGGAGGGAGGACGGGCATCCAGGGCTGACCGGTCAACGTCCAGCACCTCCCAGGGACTATGGGAAGACTGAGTGGTGGGTCTCGTCCTCTCGGGATACTTGCGCTTCTCTTTCCCCTTCTCTACAACCTGGAAAGAAGCCCCTCACCGCGTCCTACTTTTGCCCAACACGCTTTTTTTTTTGAGACAAAGTCTCACTCTGTCGCCCAGGCTGGAGTGCACTGGCGGGATCTCGGCTCACTGCAACCCCCGCCTCCTGGGTTCAGGCAATTCTCCTGCTTCAGCCTCCTCAGCAGCTGGGATTACAGGTGACTGCCACCATGCCCGGCTAATTTTTATATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGACCTGCCTGCATAGGCCTCCCAAAGTGCTGGGATTCTAGGCCTGAGCCACCGCGCCTGGCCCCAACACACTTTTTTTTTCCTGTAGGGCAACTCACATGCCTACAGGAGCTGGTTCCATAAAATAAGTTTCCCTTAACTAGGACAGAAGTAGCAGTGTCAATCACACGACACCTGTGAAGGACGGGGGCGGTGAAAGGTGACTGCCCCACCTGCAGAGCCAGCCGCTACTTAGATGTGGCAGATTGTTGCCTTGAAGGAAAGCAAGACCCTCTGTTTCCAGATCTTTCGTTGTTGTTGGTTTTTTGTTTTTGTTTTTAAGTTTAGGATTACTGAGGCATATGTAGTAAAATTTATCCATTTTACTGCTCCATTAATTTTAACAAATGTGTATTGTGTAACTACCACCACCACAGTCACCACATAGAATGTTAGTTATTGATTGATTGATTGAGATGGAGTCTCACTCTGTTACCCAGGCTGGAATGCAGTGGCATGATCTTGGTTCACTGCAACCTCCACCTCCCAGGTTCAAGCAATACTTGTGCCTTAGCCACCCCAGTAGCTGGGACTACAGGCGTGCGCCACCATGCCCGGCTAATTTTTCCATTTTTAGTAGAGATGCAGTTTCGCCATGTTGGCCAGGCTGGTCTCGAACTCCTCACCTCAAGTGATCCACCTGCCTTGGCCTCCCAAAGCTACTTATTTCTGAAACAGGGTCTCACTTTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCATAGCTCACTGCAGCCTCCAATTCCTGGGCTCAAGCAAGCCTGCCATCCGCCTCCTGAGTAGCTGGGATTGCTGGTGTGTGCCCCCCACACCCAGCTAATGTTTTATTTTAGTAGAGATGGGGGTCTCACTACATTGCCCAGGCTGGTCTTGTACTCCTGGCCTTAAGCGATCCTTCTGCCTGCTTCCCAAAGTGCTGGGGATGACAAGTATGAGCTGCCATGGCATGCCTTCAAACATTAAAGTTTTTTGAAAAAGAAGCTGGGAATCCAGATTTTTATGTGACATTTATTAAAATGTCGGCAACTCATTTTTTTAAAAGTAGTGAAAGGGTCAAAGGGGACATGTCAGCAGGTTGGATACCGCTTGTGGGATTCCAGATTGCAACCCATGAGCTTTAGGAAAATAGAATCCAAAATATCAGCTGGGTGCGGCAGCTCACGCCTGTAATCCCAGCACTTAGGGAGGCCAAGATGGGTGGATCACTTGAGGTCAGGAGTTCGAGAGCAGCCTGGCTAACATGGTGAAACCTCGTCTCTACTAAAAATACAAAAATTAGTCGGGCATGGTGGCGGGCGCCTGTAATCCCAGCTACTTGGGCAGCTGAGGCAGGAGAATAGTTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCAAGATTGTGCCACGGCACTCCAGCCTGGGTAACAGAGTTAAGACTCCATCTCAAAAAAAAAATAACAACAAAAAAACCCCAAATCTCTTACTGGTGATTGTGTGCCCCCTGTTGTGTGCCTTCCTGGACCTCTCTGAGGGAGGAAAGGGCAGGGCCTGAAACGTTCTCCCGGCCACAGCCTCCCTGTTATCCCTCCCCTCTGCTTCCTTCGCCAG
Seq C2 exon
GCCAAGGCGAACCTAGACAAGAATAAGCAGACGCTGGAGAAAGAGAACGCAGACCTGGCCGGGGAGCTGCGGGTCCTGGGCCAGGCCAAGCAGGAGGTGGAACATAAGAAGAAGAAGCTGGAGGCGCAGGTGCAGGAGCTGCAGTCCAAGTGCAGCGATGGGGAGCGGGCCCGGGCGGAGCTCAATGACAAAGTCCACAAGCTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133392-MYH11:NM_001040113:28
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.898 A=NA C2=0.986
Domain overlap (PFAM):
C1:
PF0003816=Filament=FE(18.7=100),PF0157614=Myosin_tail_1=FE(5.6=100)
A:
NA
C2:
PF0003816=Filament=PD(25.0=88.4),PF0157614=Myosin_tail_1=FE(7.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)