HsaINT0107522 @ hg38
Intron Retention
Gene
ENSG00000133392 | MYH11
Description
myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569]
Coordinates
chr16:15721422-15724409:-
Coord C1 exon
chr16:15724161-15724409
Coord A exon
chr16:15721635-15724160
Coord C2 exon
chr16:15721422-15721634
Length
2526 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGAG
5' ss Score
7.1
3' ss Seq
CTCTGGGTCTTGTGTTGTAGTTG
3' ss Score
7.16
Exon sequences
Seq C1 exon
CTCTCCGACTCGAAGAAGAAGCTGCAGGACTTTGCCAGCACCGTGGAAGCTCTGGAAGAGGGGAAGAAGAGGTTCCAGAAGGAGATCGAGAACCTCACCCAGCAGTACGAGGAGAAGGCGGCCGCTTATGATAAACTGGAAAAGACCAAGAACAGGCTTCAGCAGGAGCTGGACGACCTGGTTGTTGATTTGGACAACCAGCGGCAACTCGTGTCCAACCTGGAAAAGAAGCAGAGGAAATTTGATCAG
Seq A exon
GTAGAGGGCGTGGGGTGTCCCCCACTCTGGCCATGGACGCTGGGTTGGGGAATCAGCTCTGCAGAGTATGACGCGTGGCTCTGGCCTGTGCCTGCATCCCCTCTCCACTCTGTGGGGAGCCATGGGAGGCTGTCTTATCTTGTCTTGGGCGACCATGGAGCATTAACGCTACCAGGTCACAGTAAGGATGGCAAAGAAGCCTTGATGACTGTGACTTTTCTGGGTACCAGCACCATGAGGGTCACCTGCACACATGGTGATGCCTTAGTTTCTAGCCTGAAGAAGGAATGAGGTGCTTATTTATTCACTAAATGTATTTACTGAATACCTATTGAGTAGTATTCCAAGTAATTCAGTTTCTATACTTTTAATACCACTCTTCCCTAAGATTTCATTCTGTAAAATTCCAAGTACACAGCAAAGTTGACAGAATTGTACGGTGAACACCTTTAAGGCCACCACCTGGATTCAGTCATTGACACTGTATTATATGAACTTTATCAGATACTTATTTTGAGACAGGATCTAGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCCCCGCAACCTCCACCACTGGGTTCAAGCGATTCTCCTGCTTCAGCCTTTCATGTAGCCGGGATTATAGGAGCACACCACTATGTCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTTGCCATGTTGTCCAGGCTGGTCTCCAACTCCTGGCCTCACATGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTATAGGTATGAGCCACTATGCCCGGCCCACATATTTATTTATAAAGACTAATTCTATCTATCATGCCTTATCTCTTGGGTACATTTCAGAGCAAATTACAGATGTCAGTACATTTCCCCTTCCACACCTCAACATTGCATATTAATTAGAGTTTATTTTTAAACACAATTTTGCTTCTTTTGGGGTAAAACTTACATGTGATGAGATTCACAAATCTTAATTGTACGATAAATGGAGACCCCTGTATGACCCAAACCCCTAAATACCAACTTTTAAGATACATTATTATTTAGTAAATATGATTTAGTTTACAAGTGACTCAGGGTTATTCTAAAAATCAGTTTGAGAGGCCAGGCACGGTGGCTCACGCCTGTAATCCTAGCACTTTGGGAGGCTGAGGCAGGTGGATCACTTGAGGTCAGGGGTTTGAGACCAGCCTGGCCAACATCGTGCAACTTTGTCTCTACTAAAAATACCAAAATTAGCCGGGCGTGGTGGCGCACGCCTGTAATCCCTGCTACTCTGGAAGCTGAGGCAGGAGAATCGCTTGAACCCAGGGTGGGGTGGAGGTTGCAGTGAGCCAAGATTGCGCCACTACACCCCAGCCTGAGTGATGGAGTGAAAACCCTGTCTCAAAAATAAATAAAATGAGGATTGTACAGTGAGGCTAAATGCCAGATGCCTGCAGGTTCCCTACCCCTCCCTGACTGACCTCCTAGTGTCAGGATTCTAGATAACATCCCAGTTTCTCCTCTTCCCATCAGCTACCTCTCCTCTGGGCTGTCAGCTCATCTTCAATGCTTCGTTATCTGGTTGAAGGCCTGAGGTTGCTTTTATTTTCCTGTCACATAGAGTGTAGTGCAGTGGCACACATAGTGTGGGATTTTTGTGTTGACTGTGCCATTTAGAGGTCCCTGTCTTTGCTGAATACTGGAAGTTTGGCTTTTGGATGTTACAATTTATAATCTGCTCTGTTCTCTCTGAAGATGAGATTAACGTGAGCATGGAATGTTCTCTGAGTTGCTTCTCCAAGCAGAGAGATATGTGTGCAGGGCCACCCATGCTTACCATTTCCCTACTGAGGCTCTTAGGATACTTTTGTAAGATATTAATAGCTACTTGTGGCCATGAAACAAACTAATAACTAGCTTCTGGCAGCTTTAAATCTCACTTTGACCTCAGTGTGCTCTAAGCAACGTGGGCAGGTCTAGTGGTTTCGAAGCACAAGGATTTGGCCAGGTGTGGTGGCTCACACCTGTAATCTCCGTGCTTTGGGAGGCCGAGGCAGGAGGCTCACTTGAGGGTCAGGAGTTCGAGACCAGCCTGGTCAACATGGCAAAACCACATCTCTACTTAAAATACAAAAATTAGCCAGGTGTGGTGGTGGGCACCTGTAATCCCAACTACTCTGGAGGCTGAGGCAGGAGAATCGCTTGAACCCACGAGGCGGAGGTTGCAGTGAACCAAGACTGCACCATTGCACTCCAGCCTGGGTGACAAAGTGAGACTCCATCTAAAACAAACAAACACACAAACCAACAAAAAAAAACAAGTCAGCTGATTTCTGGCTCTGCATAAGGTTGATGTAGAAGTCAGAACGCCAGATGATTATATAAATTACTCCCATAGCTAACCTACACTGCTTACACCTGCACCTCAATACATTCAGCAGGACACAGGGCTTCCCCCGGTATTTACAATTCAGTGACGCTGACCCCGGATATGCCTAGAAGTCACCTCTGGGTCTTGTGTTGTAG
Seq C2 exon
TTGTTAGCCGAGGAGAAAAACATCTCTTCCAAATACGCGGATGAGAGGGACAGAGCTGAGGCAGAAGCCAGGGAGAAGGAAACCAAGGCCCTGTCCCTGGCTCGGGCCCTTGAAGAGGCCTTGGAAGCCAAAGAGGAACTCGAGCGGACCAACAAAATGCTCAAAGCCGAAATGGAAGACCTGGTCAGCTCCAAGGATGACGTGGGCAAGAAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133392:ENST00000300036:31
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.217 A=NA C2=0.775
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(9.6=100),PF041569=IncA=PD(58.8=80.7),PF045827=Reo_sigmaC=FE(59.4=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(8.2=100),PF045827=Reo_sigmaC=PD(6.5=12.7),PF115593=ADIP=PU(36.6=57.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development