MmuINT0103278 @ mm10
Intron Retention
Gene
ENSMUSG00000018830 | Myh11
Description
myosin, heavy polypeptide 11, smooth muscle [Source:MGI Symbol;Acc:MGI:102643]
Coordinates
chr16:14205911-14207788:-
Coord C1 exon
chr16:14207540-14207788
Coord A exon
chr16:14206124-14207539
Coord C2 exon
chr16:14205911-14206123
Length
1416 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGGG
5' ss Score
9.46
3' ss Seq
TGAGCTCTGTGTTCTTTCAGTTG
3' ss Score
9.35
Exon sequences
Seq C1 exon
CTCTCAGACTCTAAGAAGAAGCTGCAGGACTTTGCAAGTACCATCGAGGTCATGGAGGAGGGGAAGAAGAGGTTACAGAAAGAGATGGAGGGCCTCAGCCAGCAGTATGAGGAGAAGGCGGCTGCCTATGACAAACTGGAGAAAACCAAGAACAGGCTCCAGCAGGAGCTGGATGACCTGGTCGTGGACTTGGACAACCAGCGGCAACTGGTATCCAATCTGGAAAAGAAGCAGAAGAAATTTGACCAG
Seq A exon
GTAGGGCTGAAAGCTCACTGCCCTTCACACAGTTCTGTGCCACACTGTGGAGCTGCTGGGAATCTGAGTCTCCTATGGACTTTGCTGGATGCTGTGGAAGGCTATCTTGTCTCATCTTAGGTGGCCATGACATAGGAGGCTGCATGAACACATCAGAATGCTTAACATTGAGAATTTTCTAGGTACATGCACTGTGAAACCTGCTGACAGACAGCCTCAGGGCTGGCACGAGCTCTAATAAAGTGAGGGTCATTTATCTTTTCCACTCACTAGATACTGAGGAGCATTGCTGGGTGTTATAAGTAACTCTAAGCATCATTTTTTGGAACACATTATTTAATTTCTGCGCTTTTTTTTTTTTTTTGATATGGTCTCCTGTTGACCAGGTTGGCCTTGAACTCACTGTGTAGCTATAGTTGGCTTTGAACTTCTGAACTTATAATCCTCCTGCCTCTATCTTTGGAATGCTGGGATCACTGGTGTGCCATTGTCAATTTTGTGTAATACTGGAGACTGGACTCAGAGTAGGCAAACACTCTACCAACTGAGGCCCAGGCCCTTCCCTCAAAATGTCTCCTTGGTAATACCACTTTCCCCAATGCAGTCGCTGCCAGACTCAATCATTAACTCTGTGCTACATGCCTTTCGCCCTACTTTTTTTTGGGGGGGGTAGTGGGGAGAGGGTCTTACTATGTAACTCTATCCGGTCTAGAACTCATAGTGTAGACCAAGCTGATCTCAAACTTACAGAGATCTGCCTGCCCCCAGCTCCTGAGTGCTGAGATTAAAGGTGTATGCATTTATAATAAAGATGAATCACAGTAACCCATCATACTTCATTTTTTGGGTGCATTTCAAAGCAAATTAAAGACATCTATACCCTTCTCCCTTAACATTTAGCATTGCATATTAAAAGATACTCAGGCTAGTGAGAGATAGCTTACTGCCAAGATCTTGCTTCCAAGATTCATGACCTAATTTCAGCTTTTAAAACCTATTTGGTGGAAGTAGATACCAGACTTCCACAATTTGTCCTCTGATCATCATGTAGCGCATGCGCACACACACACACACACACACACACACACACACACACACAAACAAACAAATAAATAAATAAATGTAAAAAAAACCACTTGTACTTAAAAAAATAGTTTTGCAGCAAGGCATGGTGGCACAGGCCTGAAATTCTGAGTCTCAGGAAGATGAGACACAAAAATTATGAGTTTAAAGCTAGGCTGCATAGCAAGACTTTGTCTTGAAACACTAATATAAGCATTATTATTTTCTATCTTTGAGATAAATTTACATATGCTGTGATGAACACATCCTTCAAATGTGCAGGTCTTTTTCACATCTGGAGTTTGGTGAGCCTCCAGTGTGCTGGGTATGCCTCTGAGCTCTGTGTTCTTTCAG
Seq C2 exon
TTGTTAGCTGAGGAGAAGAACATCTCCTCCAAGTATGCGGATGAGAGAGACCGAGCTGAAGCAGAGGCCAGGGAAAAGGAGACAAAGGCTTTGTCTCTAGCCCGGGCCCTGGAGGAAGCCCTGGAAGCCAAAGAAGAGCTGGAGAGGACCAACAAGATGCTCAAAGCTGAGATGGAAGACCTGGTCAGCTCCAAGGATGATGTAGGCAAGAAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000018830:ENSMUST00000090287:31
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.458 A=NA C2=0.831
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(9.6=100),PF045827=Reo_sigmaC=FE(59.4=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(8.2=100),PF045827=Reo_sigmaC=PD(6.5=12.7),PF115593=ADIP=PU(36.9=57.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTCATGGAGGAGGGGAAGAA
R:
TGTTGGTCCTCTCCAGCTCTT
Band lengths:
356-1772
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types