HsaINT0107523 @ hg38
Intron Retention
Gene
ENSG00000133392 | MYH11
Description
myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569]
Coordinates
chr16:15720839-15721634:-
Coord C1 exon
chr16:15721422-15721634
Coord A exon
chr16:15721052-15721421
Coord C2 exon
chr16:15720839-15721051
Length
370 bp
Sequences
Splice sites
5' ss Seq
AACGTAAGT
5' ss Score
10.74
3' ss Seq
GCTGCCCGCTCTGCCGGCAGGTC
3' ss Score
10.1
Exon sequences
Seq C1 exon
TTGTTAGCCGAGGAGAAAAACATCTCTTCCAAATACGCGGATGAGAGGGACAGAGCTGAGGCAGAAGCCAGGGAGAAGGAAACCAAGGCCCTGTCCCTGGCTCGGGCCCTTGAAGAGGCCTTGGAAGCCAAAGAGGAACTCGAGCGGACCAACAAAATGCTCAAAGCCGAAATGGAAGACCTGGTCAGCTCCAAGGATGACGTGGGCAAGAAC
Seq A exon
GTAAGTGGCTCTGGGTGGTTTTTCTCGTCCATGTTTCGCCTGCCCACCCTCTGTGCTATTCACCAGTCCATGCGAGGCTAGCTCCTGGCCTTTTTCATAGCGAACTATCATCGGAAATGGAAGGAGGTTTTTGGACTGGTGCAGGGGCTGGGAGGGGCTGAGAATGGCAGTCGAGGATGGGTCTGAGTTGGGGGGTCCGAGGATAAGGCTGGGGTCTGAACTCTCAGGGGTCATCTTGAGTCCCGGCCATGCATCCTGTGGGAGGCCAAAGCCACCTCCCTGATCTCCTGAGGTGCCGCTCACGGTGGGTTTCTCAATCGTCTTCATGAAGTTGAGCCTCATAGAATGGGGCTGCCCGCTCTGCCGGCAG
Seq C2 exon
GTCCATGAGCTGGAGAAGTCCAAGCGGGCCCTGGAGACCCAGATGGAGGAGATGAAGACGCAGCTGGAAGAGCTGGAGGACGAGCTGCAAGCCACGGAGGACGCCAAACTGCGGCTGGAAGTCAACATGCAGGCGCTCAAGGGCCAGTTCGAAAGGGATCTCCAAGCCCGGGACGAGCAGAATGAGGAGAAGAGGAGGCAACTGCAGAGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133392:ENST00000300036:32
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.775 A=NA C2=0.859
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(8.2=100),PF045827=Reo_sigmaC=PD(6.5=12.7),PF115593=ADIP=PU(36.6=57.7)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(8.2=100),PF115593=ADIP=PD(61.6=97.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGAAGGAAACCAAGGCCCTG
R:
TCTGCAGTTGCCTCCTCTTCT
Band lengths:
349-719
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development