HsaINT0107529 @ hg19
Intron Retention
Gene
ENSG00000133392 | MYH11
Description
myosin, heavy chain 11, smooth muscle [Source:HGNC Symbol;Acc:7569]
Coordinates
chr16:15809021-15811205:-
Coord C1 exon
chr16:15810997-15811205
Coord A exon
chr16:15809130-15810996
Coord C2 exon
chr16:15809021-15809129
Length
1867 bp
Sequences
Splice sites
5' ss Seq
CAGGTATGC
5' ss Score
9.37
3' ss Seq
GTTTTCCTTGCTGTTTGCAGAGA
3' ss Score
9.05
Exon sequences
Seq C1 exon
GCCGAGCAGCTCAGCAACGAGCTGGCCACAGAGCGCAGCACGGCCCAGAAGAATGAGAGTGCCCGGCAGCAGCTCGAGCGGCAGAACAAGGAGCTCCGGAGCAAGCTCCACGAGATGGAGGGGGCCGTCAAGTCCAAGTTCAAGTCCACCATCGCGGCGCTGGAGGCCAAGATTGCACAGCTGGAGGAGCAGGTCGAGCAGGAGGCCAG
Seq A exon
GTATGCGGGTGTGGAGTTCCGAACCCAGTTTGCAGGGGGGTGATGGACAGCAGGAGTCATAGTGAAGTCAGGGAACCTCTTCCAGCATCAGTTCTGGCTTGTAAGAAGCAAGCTCTGTGATGCCTACAGTGCAGGTATGTTGTGAGAACTGAACGTAAACACAGCAAAGTGCCCTGCTGGTTCCTGGCCTAGGGCAAGCACCTAAAGTGTGAGCTGCTCTTAGCATCTCCATGGTCCTCCTGACATTAACCTGCCTTCCCAGCAGTACATATGACTTTTCCCAGCCTCTGCAGGGATAGCATGCTGACAGATCAAAAATCCAACCAGGCTGGACGTGGTGGCTCACGCCTGTAATCCCAGCAATTTGGGAGGCTGAGGCAGGTGGATCACTTGAGGTCAGGAGTTTGAGACCGGCCTGGCCAACATGGTGAAACCCTGTCTGTACCAAAAATTAGCCGAGTGTGGTGGCACATGCCTATTATCTCAGCTACTCAGGAGACTGAGGCAGGAGAATCACTCCAACGTGACACGTGGAGGTTGCAGTGAGCCGAGATTGTGCCACTGCACTGCAGCCTGGGTGACACAGTGGGACCCTTCCACACACATACACACACACAAAAAAAACCCCAAAAAACAAAAGTCCAACCGGCAGCCCATTTGGTACACACACTGGAAGCCTTCTTAATTATGGGTCGAATGAGGCATATGATCACAGCACATTTCTTACCATTGGATTCTAAGGATTCTCACCCATTCTCTTCTAGTAGCTTTTTCAGTAATTCGCACGCCCTGCAATGCACCCATTTAAAGTGTATAATTCAAGGGCTATTCATATATTCACAAACATGTAAAAACGATCACCACAGTCATTTTGAGAACATTTTCATCGGCTCAAACAGAAACCCCAGGCCATATGTGGTATTTCATGCCCATAATCCCGGCACTTTGGGAGGCTGAGGTAGGTGGGAGCAGCACTTGAGTCCAGGAGTTCGAGACCAGTCTGGGCAGCATAGCAAGACTTTTTTATTTTTATTTTTTTGAGACATAGTCTCACTCTGTTTCCCAGGCTGGTGTGCAGTGGTGCGATCTCAGCTCACTGCAACCTCCGCCTCACCCTCCCAAGTAGCTGGGACTACAGGTGCACACCACTGTACCCAGCTTGTAATTGTATTTTTTAGTAGGGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCACAGGTGATCTGCCCACCTCGGCCTCCCAGAGTACTGGGATTACAGGCATGAGCCACCACGCCTGGCCAGAGACTCCGTTTCTATGAAAAACTTTTAAAAGTCTGAGCATGCTGGTGTACGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATTGCTTGAGCCAGGAGTTCAAGGCTGCAGTGAACTATGAACTAGGGTGAAGAGCAGGCATTGGAGCACCACTGCACTCCAACCTGGGTCACACAGCAAGACCTTGCCTCCTCCCCGCAAAAAAAATAGAAACCCCATGCCCTGTAACCACTCCCTTCAGTCCCTGGCAACCATAATCTACTTTCTGTCTCTATGAATTTATCTATTCTGGACACTTGATATCAACGGAATCACACACTATGTTGTCTGCTATGTGTCTTCTTTCACTTGGCAAGAATTCCAGGCTCATCCATGCTGTGGCATGCATTGATACTTTATTCCTTTTCATGGCTGAATACTATTCCACCATCTGACTGATTCTTGAGAGGAGTCCAGATACGGGGCTCAGGAAAGCACTCAAGATGCCACCTCCAGGTGACACACCAGCTACAAGGGGTGCCACCCTCCGCTGAAACCACCTGTTTTCCTTGCTGTTTGCAG
Seq C2 exon
AGAGAAACAGGCGGCCACCAAGTCGCTGAAGCAGAAAGACAAGAAGCTGAAGGAAATCTTGCTGCAGGTGGAGGACGAGCGCAAGATGGCCGAGCAGTACAAGGAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133392-MYH11:NM_001040113:39
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.829 A=NA C2=0.824
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(8.0=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(4.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCGAGCAGCTCAGCAAC
R:
CTGCTCCTTGTACTGCTCGG
Band lengths:
318-2185
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)