HsaINT0107533 @ hg19
Intron Retention
Gene
ENSG00000133392 | MYH11
Description
myosin, heavy chain 11, smooth muscle [Source:HGNC Symbol;Acc:7569]
Coordinates
chr16:15796992-15802698:-
Coord C1 exon
chr16:15802660-15802698
Coord A exon
chr16:15797981-15802659
Coord C2 exon
chr16:15796992-15797980
Length
4679 bp
Sequences
Splice sites
5' ss Seq
CAGGTATCA
5' ss Score
7.33
3' ss Seq
TGTTTTCTTACAACCCACAGGCG
3' ss Score
7.94
Exon sequences
Seq C1 exon
AGGGCCCCCCCCACAGGAAACTTCGCAGTGATGCACCAG
Seq A exon
GTATCATGCCTTCAGCTTCGCAGCTGTGTGTTGTCTCAGTATCCATTTCTTTTCTGCCCAATGCGCCCCTCTGCCCACCCCAATTTTTAAACCCTTGCACATTTCCACGAGATTCTTGCAAAATCTGGAGGCTTGGATATCTTTGTGCAAAGCTTTCATTGAAACCAAGATCAGGATGACAAATAGACCTCATCTCTTGACCCACTGTCCTTCCTGCCTCTGGGCAGCACATGTGACATGACACCCAACAGTGTGCGCCCTTATCACTGCATCTTGACGAGATGGCAGAGGCTGTGTGTGTAGCTTGGATTTTTCTTCCTTTCATGCCAAAAGCCACTCTTACGTGGTTAGGGCACTCAGCAGTGCTGTCCTCCCTTGTCCAGTGAAGACACTGCACTGAATGAATATGACAGTTCCACTATCTGGGCACATTCCTGGAGAACGTACTTGGCTTCTAGTTGGCTGGTCTGGGTCACAAGTCAGAGATCACAAAGTTCACGGTAACTGCGGCGCGGCAACCAGTCCTCCCATGATTCAGCTTTCACAGGCTTGTCTGCGAAGGAAATGAGCTCACTGCGATGTCTGACAAATGCCGGGGGCTGCACGTGGCTTGAGTGATGTCTAGCTACAAACTGCATTTTCAGCACACGGGGTGGAAGCTGACCACCGCAAAGCCAAGCACAGTCCTGGCAGAGCCTTTTCTGGAGGCTTCACGGGCATGTACATGTTCAGGGACTGGGGAGTGGATACCCAAGACTCAAGGATGCACACAGGGCCCTTCCCAAGAAAGCATGAAGAGGTCTCTGCTGCTCTGGGATTTTGCTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGGAGTGCAATGGCGCAATCTTGGCTCACCGCAACCTTTGCCTCCTGGGTTCAAGCGATTCTCCTACCTCAGCCTTCTGAGTAGCTGGGATTACAGGCTCCCGCCACCTCGCCCAGCTAATTTTTGTATTTTTATTAGAGACAGGATATCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACTTCAGGTGATCCGCGCGCCTTGGCCTCCCCAAATGCTGGGATTACAAGCATGACCAACTTTTCACAGGTGAAGTTAGGCCATGTGGATCTGACTTCACCTCATGGAGAGGCCAAACCAACCCTCATTTGTGTCCATCTTCATTTTTGGAGAATCTCAGCTTTGCTGTCACTACCAAAATACTTAAAGCGCAGGGTGAGGTCTTGTTAAGAGCCAGTTTTGTGGGGGAGCAGATGAGTTTCTAGGACACTTCAAGCAGCTCTCCTACCAGCTGATTGGGATCATAGGATAAGCCAAATTCCAGGGTGGGCTGAAGTGCAGAACCCACTGGTCAGTGGGAAACTGAGTCCTTGCAAACTAGCAGGTGCTTACACTCAAGATGATTCCCGAGGCCTTGGATAAGCTGAGTCCACGAATAGAATCCAAATGCTAGGCCAGGCACAGTGGGTCATGCCTATAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATAACTTGAGGTCAGGACCAGCCTGGCCAACATGGTAAAACCCCGTCTCTCCTAAAAATACAAAAATTAGCCAGGAGTGGTGGCATGTCTGTAGTCCCAGTTACTTGGAAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAGGCTGCAGTGAGCCAAGATCACGCCACTGCACTCCAGCCTGGGCAACACAGCGAGACTCTATTTCAAAAAAAAATTCCAGATTCTCCAGGATCAGACCCTTTAAGAAAACCTTTAGGGGGGTCCCTTAGTTCCTGTAACAGGTATAGTTGGTGTCAACCTTGGTCTAGGATTTGAAACCAGTTCCAAGAAAAGCACTTCAGCCAAAACAGAGTATCTTGCAGGCTGACAGCCAAGCAAGGAGCTTCAACGGCCCAGGGCACAATGTATTTCTTAGGTCAAGGGAGCAAATTTATCCATTAAGCTTTTCCAGTTAGCAAATAGACTCTTCCAAGAGCCAAAAAGAGAGTGCCTAGAGCACTGATGTGGAGGTTAGGGACTACTTCCCAGCTCATCAGATTTTTTTTTGTTTTTTTTTTTGGAGACAGTCTTGCTGTTTCCCAGGCTGGAGTGCAGTGGCACAACGTTGGCTCACTGCAGCCTTCACCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTGACTGGGATTCCAGGCGCCTGCCACCACGCACGGCTAATTTAGTATATTTAGTAGAGACGGGGTTTCACCATATTGGCCAGGATGGCCTCGAACAACTGACCTCACGAGTGATCTGCCCACCTCGGCCTCCCCAAGTGCTGGGATTACAGGCATGAGTCGCAGCAACTGGCCAACCCATCAGGGTTTGAACCTGGAGTTAAAACTGTGACGAAGAGAGCTGTGTGGGGAGCGTACAGGGAACAGTCAAACTGCTGCTCCTCTGCGCTGAATTTGAGCATCCTTCTGAGTCAAGCGCTTGGAAAACAGTGCTAAAAAAGAAAAAGACTTAAGGGTCACATCTAGAGAGAGAAGGATGGAGAGTTCTCTAGTAGGGCTGCAAGTCCAGAAGCTTCTCTGTGAAGCTGGGCTAGGAGTGTTTACTTTGAAGTGGCTGCAGCTTTAAGTATTTATTCCTGATCGCTGCACTGCGGGAAGTCCCATCCTTTATAGCCAGGTGGGCTTTCCCAGCCGGGGTCTCTCCCATCCTCTGTCAACAAAAGGGTCATTTGCGAATTCCTCTTCTCAGTGATCATGAATCTCTGGGCCTTGATTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCACCCTGTCGCCTAGGCTGGAGTGCAGTGGCCACATCTCGGCTCACTGCAAGCTCCGCCTCCTGGGTTCATGTCATTCTCCTGCCTCAGCCTCCCTCCCGAGTAGCTGGGACTACAGGCACCCGCCAGCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACACGGTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCATGATCCGCCCGCCTCAGCCTCCCAAAGTGCTGAGATTACAGGTGTGAGCCACCATGCCCAGCCGAGTTGTTCCTTTTGACTAAAGAATTGGTCACTGAGTTGTGTTCATCCTTATGGCTTCTTATCCAACCCTTGCGTGGGGAGCAAAAGTCTGCTCTCTTCTTTGATGTCCTAAAATAAGACCTGTCTTCCGATTCAGGTCAAACAGGGCCAGATGGCCAGAGCCCAACATAATTATTTGTTGCGGTTGCTGAAAAGAGTTAAGTGTTTCTTCTGAACGGTGAAGGCTGGCAGCAGGCAGATCTGATTTTTCCTTCTTCTGCCCACTCTCTTCCTCCTACCCAAAGTCTCCCCTCACGTGACCAGCCCTTCCTGTGAAGTCGAGGTGATAAACTCAAGAGAGAACCAGCGCAGAGAGGAGATGGCAGCATTAAGGAGAGACAGGGGTGTCCTACTGGCTGGAGCTAAAATCCACCTCAGAGGCCAGGTGCACTGGCACACACCTGTAATCCCAACACTTTGAGAGGCTAAGACAGGTGGATCGTTTGAGGCCAGGAGTTCAAGACCAGCCTGGGTCACATGGCAAAATCCCATCTCTGCTAAAAATACAAAAATTAGCCAGGCGTGGCAGTGTGCACGTGCATGTAGTCCCAGCTACTCAATACTGAGGCTCAAGGACTGCTGGAACTCAGGAGGCAGAGGTTGCAGTGAGCCAAGATCATGCCACTGCACTCCAGCCTGGGTGAGAGAGACTCTTAAATTTCTTTTTTAAATCCACCTTGAAGGCCAGGTGTGGTGGCCCACGCCTGTAATGCCAGCGCTTTGGGAGGCCAAGGTAGGAGAACTGCTTGAGCTCAGGAGTTCCAGACCAGCCTGGGCAACAATATCAAGACCTCATCTCAATTTAATAAAATAATCCACCTTGGATTAACACGTATAATTTCCTTTTCTAATATTCACTGGGCACCTGTTTTACGCCATGTGCGGTATGTTCCACGATCAGCAAAACAGATGCAGCAGTCCCTGCAGTGGGGAAAACTCAGTCCATGAACATTCACACCAGCAGGGGGTGCTGTCTCGCCTTTTAACCAGGGAGCCCCTCTGTGTCCTTCTCAAGGCTGCCCTTGTCCATTTCACCTTCTTCCAATTCAAATCTTGAAAACTCACCTCTAAGGCGAATGGGGGTGAGGAGATACAGAAGAAAAACAGTATGTTCTCTCTTCAACTCTGCCCCATGGGCTATGAATAAAGTCAGAAGACAAAATCCCCTGCTTGGTTTTTGGCGTTTTTTTCCTATTCTAAATCAAAGACCACAGCAGACCAGAATCCTGTGGCTTCTCAAATGACCAAGCCTGACATATTGAAAAGCAGATCGTCTTGCTTTGAAAAACCTTCTCCACCCACCCCCGCAACCAATTTCAGCTGATTAAATTCAATCACTCATGCCTTAAGACTGGCAATGATTTGTTGACTTCAACTTGAATATCTGCATCTTATTTGTGCCGTGTGTGTTTTCTGCCATAAAAAAAATTTATATTGCAATAGGACTATAGCTACAAGTTTAAAATAGATTTATAAAAAATCTATCCCAACCATGAAGATTTCTTTGCTAAATAATGTGTTTTCTTACAACCCACAG
Seq C2 exon
GCGAGGAAACGAGACCTCTTTCGTTCCTTCTAGAAGGTCTGGAGGACGTAGAGTTATTGAAAATGCAGATGGTTCTGAGGAGGAAACGGACACTCGAGACGCAGACTTCAATGGAACCAAGGCCAGTGAATAAGCAACTTTCTACAGTTTTGCACCACGGCAAGAAAACCAAAAACCAAAACAAACAAACAAAAAAAACCCAACAACAACCCAGAACAAAGCAAAACCCAGCAGACTGTACTTAGCATTGTCTAAATCCATTCTCAAATTCCAAATATCACAGACACCCCTCACACAAGGAATATAAAAACCACCACCCTCCAGCCTGGGCAACGTAGTAAAACCTCATCTATACAAGAATTTAAAAATAAGCTGGGCGTGGTGGTACACACCTGTGGTCCCAGCTACTAGGGAGGCTGAGCCAGGAAGAACGCTCCAGCCCAGGACTTCGAGGCTGCAATGAGCTATAATTGCATCATTGCACTCCAGCCTGGGCAACAGAGACCCTGTCTCAACCACCACCACCACCACCACCCCTACTACCCCTGTATTCAAGGTAAAAATTGAAGTTTGTATGATGTAAGAGATGAGAAAAACCCAACAGGAAACACAGACACATCCTCCAGTTCTATCAATGGATTGTGCAGACACTGAGTTTTTAGAAAAACATATCCACGGTAACCGGTCCCTGGCAATTCTGTTTACATGAAATGGGGAGAAAGTCACCGAAATGGGTGCCGCCGGCCCCCACTCCCAATTCATTCCCTAACCTGCAAACCTTTCCAACTTCTCACGTCAGGCCTTTGAGAATTCTTTCCCCCTCTCCTGGTTTCCACACCTCAGACACGCACAGTTCACCAAGTGCCTTCTGTAGTCACATGAATTGAAAAGGAGACGCTGCTCCCACGGAGGGGAGCAGGAATGCTGCACTGTTTACACCCTGACTGTGCTTAAAAACACTTTCACTAATAAATGGTTATAAATCACAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133392-MYH11:NM_001040113:42
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=0.941
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=PD(0.1=9.1)
A:
PF0157614=Myosin_tail_1=PD(0.1=9.1)
C2:
PF0157614=Myosin_tail_1=PD(0.1=2.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)