HsaINT0107589 @ hg19
Intron Retention
Gene
ENSG00000105357 | MYH14
Description
myosin, heavy chain 14, non-muscle [Source:HGNC Symbol;Acc:23212]
Coordinates
chr19:50760556-50762522:+
Coord C1 exon
chr19:50760556-50760743
Coord A exon
chr19:50760744-50762400
Coord C2 exon
chr19:50762401-50762522
Length
1657 bp
Sequences
Splice sites
5' ss Seq
AGGGTGAGT
5' ss Score
9.25
3' ss Seq
TGTCCGTCCGCTCTCCCCAGGCC
3' ss Score
11.79
Exon sequences
Seq C1 exon
TGGAGGGCATCGTGGGGCTGGAACAGGTGAGCAGCCTGGGCGACGGCCCACCAGGTGGCCGCCCCCGTCGGGGTATGTTCCGGACAGTGGGACAGCTCTACAAGGAGTCCCTGAGCCGCCTCATGGCCACACTCAGCAACACCAACCCCAGTTTTGTCCGCTGCATTGTCCCCAACCACGAGAAGAGG
Seq A exon
GTGAGTGACTCAGCCTGGGGAGGAAGGGGTGGCTGTGGCTGTGGGTTAAGGTTTGGCCTCTGGACTTGGCTGGAGCCACATCTGATTCGAGGACCCTCAAATTAGCTGTGTGGCTTTGAGCAAATTGCTTCTATTCCTAGGCTCAGGGTCCGGTTGGGAAAATTCATGCATTCATATGACTTAATGTATTAAGCATCTACTGTGCTGGGAACAGGTACTGGGGAGGCATTGGAGAGAAAGGCACAGCCAACTCCTGTTCTCAGGGAGCTCACAGTCTGATGGGGAGCATAGACATTCATCTAACCATCCAAAATGAACGTCCAGTTAAATCTGTAGGGGTGGTGAGTATCACACAGGGCTTGATCTGGTCAGTGAAGTTAGGGAAGGTTCCCTGGGGGACGTGATGACTGAGCCCTGAAGGATACGTGATATTCCAGGCAGAGAAGAGTTTGTACAAAGGCCCAATGGTAGGTTGGAGCACGCGAGGTACAAGGGATAGAGGAAGGCCATCAGGGCTGGGCTTGTTGCATGGGTGTGACAAGACCATGGCCAGCCTCACTGGCCACTGATTTTCATGTTGAGAAAATCAGAGAATGGGCCCTACAGAGAAGGGTCAATGGGAATGGAAAACAACATGTTTGCCATGTTGCCCAGGCTGCTCTCGAACTCCTGAGCTCAAGCGATCCACCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCCAGCCTGAGATCCCATATTTTATCAAATCTAAGCCATGTATTCCTCCCCACTAGCGTCTCTGAAGTCGAGATGTAGCTTAGTCAACGGCCTGTCAGGGTTTAATTACCAGTCTTTTTCCTTTCTTGGTGGCATATTTAACGACAGCGTGTGCCACTGGAATTTTTGTACTGTTTAGATTTTTGCCATTTGTGCATTACTGTTGAAAAGAGAAAAGGCGGCCTGGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGAGGACTGCTTGAGCCCAGGAGTTCAAGACCAGCCTGGGCAATGGCGAAACGCCGTCTCTACTCAAAATACAAAAATTAGCTGGGCATAGTGGTGTGCACCTATAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAAGCTCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCTGAGATCATGCCATTGCACTCCAGCCTGGGCAACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAACGAACAAACAAACAAACAAAAACCAAAAAAACATGATTTACCAGCTTTGGACAGACATCAGCTTCCCAGGAGGCCTTTTGGCGACTCTCTTGCGTGCAAATTCAGCCCCACCCACATCCCTCCCTGCGGATCTTTTCTCCTTAGCACTTAGTATTTCTTCTTTATTAGTGACTGCTTCACCTAGGGTATTTCTAGTTTCTCCTACTGAACTCTCAGTTCCCCAGGGCAGGATTTCCCCCTGGTTTGAGCATTGCTGTCTTCCCAGGGCCTAGAACCGTTCCTAGGCACCTAGTAGGTGCTCAGTAAATTACATGTGGAAACAGGAAATTGCCAAGCTTGACCGTTTGGCGCCCCCGTGTGGCCGCCGCTGACCCCCGCGTGTCCGTCCGCTCTCCCCAG
Seq C2 exon
GCCGGGAAGCTGGAGCCACGGCTGGTGCTGGACCAGCTTCGCTGCAACGGGGTCCTGGAGGGCATCCGCATCTGTCGCCAGGGCTTCCCCAACCGCATCCTCTTCCAGGAGTTCCGGCAGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105357-MYH14:NM_001077186:17
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.270 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(8.6=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(5.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCATCGTGGGGCTGGAAC
R:
CTGCCGGAACTCCTGGAAGAG
Band lengths:
302-1959
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)