HsaINT0107694 @ hg38
Intron Retention
Gene
ENSG00000125414 | MYH2
Description
myosin heavy chain 2 [Source:HGNC Symbol;Acc:HGNC:7572]
Coordinates
chr17:10531633-10533421:-
Coord C1 exon
chr17:10533285-10533421
Coord A exon
chr17:10531889-10533284
Coord C2 exon
chr17:10531633-10531888
Length
1396 bp
Sequences
Splice sites
5' ss Seq
AAGGTATAA
5' ss Score
7.08
3' ss Seq
TTGCATCAATTAAATTTCAGGGA
3' ss Score
7.02
Exon sequences
Seq C1 exon
GTCTTTTTCAAAGCTGGTCTTCTGGGGCTCCTAGAGGAGATGCGAGATGACAAGCTGGCCCAGCTGATTACCCGAACCCAGGCCAGGTGCAGAGGGTTCTTGGCAAGAGTGGAGTACCAGAGGATGGTGGAGAGAAG
Seq A exon
GTATAAAAAATATGTTTATTCACATATTCCATCTTCAAAAACATATTTGAAATGGCTTACAGTTAAGACTCAGCTTATGATAAGGACACTAAAGAAGAAATGAATAAGAGTCCTATAATGAAGTGGGAATACACATGTACCAGAAAACTTAAGGAAGGAACCATCACCATCTGATTGCATGGGTAAAAACTTGAGAAGTTAGGTAAGAAGTGTGTACTTCTTATCTAATAAGATAAAATACACCAGTGAGTAAGCAGAAGCAAACTTTTGCCCTAGCACCTGTTTCTAATATGAATTTATTGGACAGATCATTAGATAAGGGACATTGACCTGCAAAACAGACAGTATACTCAAGAGTGCTTTTACACAGGCTGTAGAGACAACTTTTTCCCTCTGATCATTTATATTATCAAACTCTCATGATTTAAAATATTAGGGGCCATTTATCTGTGAAAGACTTTTTGCAGTAAGTTAACACAATGCATCAGGGAATGTAGCTATTTGGTGATCTAATTTGATGCAAGGACAGAGTTCAAAGACTATAGAGCCAGGTGTCTCAAAGTACAGGATGTCTGTGATCAGGACCATTTCTCCATGTTGAGAAAGGCATTTTACATTGCCACCTATACATCTACACATATACATATGTGTATGCAGATATATAAATAATTTATATGAAGCAAATTTTATTTTTACCACTTGTAATTATGCTAATATTTTCAACTATATTCCATTTTATTAAAAATAATAAATTTTGGTCATGATCCACGATATATATATATTTGGGTAATTGTCTATATATGGGGTAATTAGCTGTAAAAATCATTTAGATGAAAACAAAAGTGGTATTAGAGAATAGAATACAAAATTCACACAACATTAACATATAAAGCCAGATATTTTCTAAGAAATTCTGAGTTTTTAATATCTCCTGCCCCATATACCCCTAAAGAGCTGTGTTCCCCCTTCACTGCCCTTAGTGGTGTTTTAGTAGCAATGTTTGAGAAGCACTGACATACAGCAAGGCTTCTCAAAGGGTGCTCCTTGGACTTGCAACATCAGCATTTCTTGCAAACTTGTTAAAAGTGCCAATTTTCAGGCTCCACCCTAGATCTTCTGAATCTGAATCTGAATCTACGGAGGTGAGGTTCAGGAGTCAGTATTTTAACAAGCCCTTCAGGTGATTCTTATGCATGCCAAAGTTTGAGAAGCAGTGATGTAGAGAAATGAGTGACCTTAGCAAGACCTTGACCATCATCCCGAAATAGAATTTTTTCATCTGCATGTTTGAAAGCAGAGTAGGAACAAGGTGAAGCAGAACCTCCAACTCTCACTGCCAAGGTTTCATCCCATTGCATCAACCACACAATACTAATTTGCATCAATTAAATTTCAG
Seq C2 exon
GGAGGCCATCTTCTGTATCCAGTACAATATCAGATCCTTCATGAATGTCAAGCACTGGCCCTGGATGAAACTCTTCTTCAAGATCAAGCCTCTGTTGAAGAGTGCAGAAACTGAGAAGGAGATGGCCACCATGAAGGAAGAATTTCAGAAAATTAAAGACGAACTTGCCAAGTCAGAGGCAAAAAGGAAGGAACTGGAAGAAAAGATGGTGACGCTGTTGAAAGAAAAAAATGACTTGCAGCTCCAAGTTCAGGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125414:ENST00000245503:21
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.023
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PD(0.4=6.5)
A:
NA
C2:
PF0157614=Myosin_tail_1=PU(30.8=61.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGATGCGAGATGACAAGCTGG
R:
CCTGAACTTGGAGCTGCAAGT
Band lengths:
354-1750
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development