HsaINT0107726 @ hg19
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin, heavy chain 3, skeletal muscle, embryonic [Source:HGNC Symbol;Acc:7573]
Coordinates
chr17:10545557-10546040:-
Coord C1 exon
chr17:10545734-10546040
Coord A exon
chr17:10545628-10545733
Coord C2 exon
chr17:10545557-10545627
Length
106 bp
Sequences
Splice sites
5' ss Seq
ATGGTAAGA
5' ss Score
9.48
3' ss Seq
CCCTCCCTTATTGCTTTCAGCTG
3' ss Score
8.37
Exon sequences
Seq C1 exon
CCTATGGGCATCTTCTCCATCCTGGAAGAGGAGTGCATGTTCCCCAAGGCAACAGACACCTCCTTCAAGAACAAGCTGTATGACCAGCATCTTGGAAAGTCCAACAACTTCCAGAAGCCCAAGGTGGTCAAAGGCAGGGCCGAGGCTCACTTCTCACTGATCCACTATGCGGGCACCGTGGACTACAGTGTCTCAGGTTGGCTGGAGAAGAACAAGGACCCTCTGAACGAGACTGTGGTTGGGCTGTACCAGAAGTCTTCCAACAGGCTCCTGGCACACCTCTATGCCACGTTTGCCACGGCGGATG
Seq A exon
GTAAGAGGAGTGCTTTGTGTCCATGTGATTTCCCTCCATTTGTTCCACAGTAACAAAAAACCTTTTAGATTCACCTACAGCACGTGCCCTCCCTTATTGCTTTCAG
Seq C2 exon
CTGACAGTGGAAAGAAGAAAGTTGCCAAGAAGAAGGGTTCTTCCTTCCAAACTGTCTCTGCCCTTTTCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063-MYH3:NM_002470:15
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.042
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(15.0=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(3.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGCCCAAGGTGGTCAAAGG
R:
GGGCAGAGACAGTTTGGAAGG
Band lengths:
257-363
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)