HsaINT0107730 @ hg19
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin, heavy chain 3, skeletal muscle, embryonic [Source:HGNC Symbol;Acc:7573]
Coordinates
chr17:10543650-10544003:-
Coord C1 exon
chr17:10543880-10544003
Coord A exon
chr17:10543787-10543879
Coord C2 exon
chr17:10543650-10543786
Length
93 bp
Sequences
Splice sites
5' ss Seq
AAGGTAATG
5' ss Score
8.99
3' ss Seq
TCACCCTTCTGCCCCATAAGGTG
3' ss Score
5.61
Exon sequences
Seq C1 exon
ATACCGAGTGCTGAATGCCAGTGCAATCCCTGAGGGACAATTCATTGACAGCAAGAAAGCCTGTGAAAAGCTTCTGGCATCCATTGATATTGACCACACTCAGTACAAATTTGGACATACCAAG
Seq A exon
GTAATGCATCAGTTCTGACAGATGCTGGCCTTTTCGTCCTCTTGACACAGCTTCTCTAGGAAACTGACTCATGTCACCCTTCTGCCCCATAAG
Seq C2 exon
GTGTTCTTCAAGGCTGGCTTGCTGGGAACCCTGGAAGAGATGCGGGATGACCGCCTGGCCAAACTAATCACCCGGACACAAGCTGTGTGCAGAGGGTTCCTCATGCGTGTGGAATTCCAGAAGATGGTGCAGAGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063-MYH3:NM_002470:19
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(6.0=100)
A:
NA
C2:
PF0006316=Myosin_head=PD(0.4=6.5),PF0061222=IQ=WD(100=45.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATACCGAGTGCTGAATGCCAG
R:
GTCATCCCGCATCTCTTCCAG
Band lengths:
175-268
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)