HsaINT0107732 @ hg19
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin, heavy chain 3, skeletal muscle, embryonic [Source:HGNC Symbol;Acc:7573]
Coordinates
chr17:10543313-10543786:-
Coord C1 exon
chr17:10543650-10543786
Coord A exon
chr17:10543569-10543649
Coord C2 exon
chr17:10543313-10543568
Length
81 bp
Sequences
Splice sites
5' ss Seq
GAGGTCCAG
5' ss Score
-3.78
3' ss Seq
AAGCAATGTCTTGTTTTTAGGGA
3' ss Score
6.32
Exon sequences
Seq C1 exon
GTGTTCTTCAAGGCTGGCTTGCTGGGAACCCTGGAAGAGATGCGGGATGACCGCCTGGCCAAACTAATCACCCGGACACAAGCTGTGTGCAGAGGGTTCCTCATGCGTGTGGAATTCCAGAAGATGGTGCAGAGGAG
Seq A exon
GTCCAGCAGGGTCTTTGTTCAGACATGAGCTCTTTGGGGAAGGGGAGTCTCTCTCAGAAATAAGCAATGTCTTGTTTTTAG
Seq C2 exon
GGAGTCCATCTTCTGCATCCAGTACAACATTCGCTCATTCATGAACGTCAAGCACTGGCCCTGGATGAAACTCTTCTTCAAGATCAAGCCCCTCCTCAAGAGTGCAGAGACTGAGAAAGAGATGGCCACCATGAAGGAAGAATTCCAGAAAACCAAAGATGAACTCGCCAAGTCGGAGGCAAAAAGGAAGGAGCTAGAGGAAAAACTGGTGACTCTGGTCCAAGAGAAGAATGACCTGCAGCTCCAAGTACAAGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063-MYH3:NM_002470:20
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.105
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PD(0.4=6.5),PF0061222=IQ=WD(100=45.7)
A:
NA
C2:
PF0157614=Myosin_tail_1=PU(26.9=61.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTCATGCGTGTGGAATTCCA
R:
TCCTTCATGGTGGCCATCTCT
Band lengths:
177-258
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)