HsaINT0107733 @ hg38
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:7573]
Coordinates
chr17:10639560-10640251:-
Coord C1 exon
chr17:10639996-10640251
Coord A exon
chr17:10639803-10639995
Coord C2 exon
chr17:10639560-10639802
Length
193 bp
Sequences
Splice sites
5' ss Seq
GCTGTACGT
5' ss Score
5.68
3' ss Seq
ATTATTCTTTTTTTTTTAAGGAA
3' ss Score
9.21
Exon sequences
Seq C1 exon
GGAGTCCATCTTCTGCATCCAGTACAACATTCGCTCATTCATGAACGTCAAGCACTGGCCCTGGATGAAACTCTTCTTCAAGATCAAGCCCCTCCTCAAGAGTGCAGAGACTGAGAAAGAGATGGCCACCATGAAGGAAGAATTCCAGAAAACCAAAGATGAACTCGCCAAGTCGGAGGCAAAAAGGAAGGAGCTAGAGGAAAAACTGGTGACTCTGGTCCAAGAGAAGAATGACCTGCAGCTCCAAGTACAAGCT
Seq A exon
GTACGTGTTTAGCAATCTTTTTTTTTTTTTTAACTCTTCTAGATTTGATTATTTATTTAGAAAAATTGAGTTATTGGTGGGGATTTTTGCTTTTTAGTTGAAATGCTTCATAAAGAACTTCATATATAGTGAAATACTGGAATGTCGCAAACCTTATATCATTCAACGAAGTTATTATTCTTTTTTTTTTAAG
Seq C2 exon
GAAAGCGAAAATTTGTTGGATGCTGAGGAAAGATGCGATCAGCTGATCAAAGCCAAATTCCAGCTCGAGGCCAAGATCAAGGAGGTGACAGAGAGAGCTGAAGATGAGGAGGAGATCAATGCTGAGCTGACGGCCAAGAAGAGGAAACTGGAGGATGAATGCTCAGAGCTCAAGAAAGACATTGATGACCTTGAGTTGACCCTGGCCAAGGTTGAGAAGGAGAAGCATGCCACAGAGAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063:ENST00000583535:22
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.105 A=NA C2=0.321
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=PU(26.9=61.6)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(40.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCTCCTCAAGAGTGCAGAGA
R:
CTTGGCCTCGAGCTGGAATTT
Band lengths:
242-435
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development