HsaINT0107734 @ hg38
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:7573]
Coordinates
chr17:10639298-10639802:-
Coord C1 exon
chr17:10639560-10639802
Coord A exon
chr17:10639475-10639559
Coord C2 exon
chr17:10639298-10639474
Length
85 bp
Sequences
Splice sites
5' ss Seq
AAGGTATTC
5' ss Score
6.8
3' ss Seq
TGCTTGCGAATTCTTCTTAGGTT
3' ss Score
6.68
Exon sequences
Seq C1 exon
GAAAGCGAAAATTTGTTGGATGCTGAGGAAAGATGCGATCAGCTGATCAAAGCCAAATTCCAGCTCGAGGCCAAGATCAAGGAGGTGACAGAGAGAGCTGAAGATGAGGAGGAGATCAATGCTGAGCTGACGGCCAAGAAGAGGAAACTGGAGGATGAATGCTCAGAGCTCAAGAAAGACATTGATGACCTTGAGTTGACCCTGGCCAAGGTTGAGAAGGAGAAGCATGCCACAGAGAACAAG
Seq A exon
GTATTCTTATTGTAGGTGTGTCTAGCTTGATATAGTCATTGCAAACTAAACTTTAAGCTTATAATTGCTTGCGAATTCTTCTTAG
Seq C2 exon
GTTAAAAACCTTACTGAGGAACTCTCTGGGTTAGATGAAACAATTGCAAAGTTAACCAGAGAGAAGAAGGCCCTCCAAGAGGCGCACCAGCAGGCCTTGGATGACCTCCAAGCTGAAGAAGACAAAGTCAATTCTTTGAACAAAACCAAGAGCAAACTGGAACAGCAAGTGGAAGAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063:ENST00000583535:23
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.321 A=NA C2=0.729
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(40.6=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=PD(28.8=93.2),PF0157614=Myosin_tail_1=PU(45.5=50.8),PF0003816=Filament=PU(6.9=32.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGAGGATGAATGCTCAGAGC
R:
GAGGGCCTTCTTCTCTCTGGT
Band lengths:
170-255
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development