HsaINT0107737 @ hg19
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin, heavy chain 3, skeletal muscle, embryonic [Source:HGNC Symbol;Acc:7573]
Coordinates
chr17:10541360-10542280:-
Coord C1 exon
chr17:10542190-10542280
Coord A exon
chr17:10541750-10542189
Coord C2 exon
chr17:10541360-10541749
Length
440 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGGA
5' ss Score
9.79
3' ss Seq
TGAACGGCTGCCCTCCACAGGCT
3' ss Score
7.53
Exon sequences
Seq C1 exon
GAAAGATTTTGAATATTGTCAACTTCAAAGCAAAGTGGAAGATGAGCAGACACTGGGCCTCCAGTTTCAGAAGAAAATCAAAGAGTTGCAG
Seq A exon
GTAGGAGCCCTCTGCATTTCTCTCTTCCATGTGAGGCCACTTACAGTGAGCTGGGTGCTGTCTGCTATAAGCCATTTAGAGAAAGTGGGCAAGACTGTGGGGCCACCTGCCTCATGGTTCCCTTTCTGCTAGGCTGGCCTGGCCATGATGAACCATTTCCCCAAAACATCTGATTAAATACTTTAATCCATAATTAAAGTATTTAAGTTAACAACTAAAAGTTAACATTTAGTTGGTGGAAAATGTTCAGGTTTGGTCACTGCAGGAGTAATTACCATGTTGGGGCAGAAAAAATTCCTGTGAAAGGAAATTTGCAGTATTCATTGGAGGGGAGTCTAAGACTCAGTTTGTCTAATGGGAAGGGAAACCAGCCTGTTCTTGGCAATCAGAGTCCCCGCGGTGAACCCACTGCCCACGGGGTGAACGGCTGCCCTCCACAG
Seq C2 exon
GCTCGAATTGAGGAGCTGGAAGAGGAGATAGAGGCGGAGAGGGCCACCCGCGCGAAGACAGAGAAACAGCGCAGCGACTATGCCCGGGAGCTGGAGGAGCTGAGCGAGCGGCTGGAGGAGGCGGGAGGCGTCACCTCCACGCAGATAGAGCTCAACAAGAAGCGGGAGGCGGAGTTCCTGAAGCTGCGCAGGGACCTGGAGGAGGCCACACTGCAGCACGAAGCCATGGTGGCCGCGCTGAGGAAGAAGCATGCGGATAGTGTGGCCGAGCTTGGGGAGCAGATTGACAACCTGCAGCGGGTCAAGCAGAAGCTGGAGAAGGAGAAGAGCGAGTTCAAGCTGGAGATCGATGACCTCTCCAGCAGCATGGAGAGTGTGTCGAAATCTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063-MYH3:NM_002470:25
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.323
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(3.5=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(15.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGATGAGCAGACACTGGGC
R:
CAGGTTGTCAATCTGCTCCCC
Band lengths:
348-788
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)