HsaINT0107744 @ hg38
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:7573]
Coordinates
chr17:10633591-10634182:-
Coord C1 exon
chr17:10634017-10634182
Coord A exon
chr17:10633716-10634016
Coord C2 exon
chr17:10633591-10633715
Length
301 bp
Sequences
Splice sites
5' ss Seq
AGCGTAAGC
5' ss Score
6.06
3' ss Seq
TGAAACTTACTTCTTTACAGAGG
3' ss Score
6.49
Exon sequences
Seq C1 exon
GTGTTGGCAGAGTGGAAGACAAAGTGTGAGGAGAGCCAAGCAGAGCTGGAGGCATCCCTGAAGGAGTCCCGCTCCTTGAGCACTGAGCTCTTCAAACTGAAAAATGCCTACGAGGAAGCCTTAGATCAACTTGAAACTGTGAAACGGGAAAATAAGAACTTAGAGC
Seq A exon
GTAAGCTATTCGAAACCCTCTGAAACCTCCTCCTTTCATGCTCTATTGCTCGAGAGCATGCTGGCGTGGGTGTGGCTTCATCACTCAGTTTCCTGCACACATGTGTGTTAATGCACATGCAGAAAGTGTTCACCATCTGACGGGTTACGTTTTAGCCTCTCTCTGTACAATATCTTATCTCTAGGAAGCAGGAAACCTTAGGATTATAATAAACCAGGTAAAAAGCATTGAGTCAATGCTTTGCATGTCTGGAAACCCACGCAGAGGCGCTCATATGCAACTGAAACTTACTTCTTTACAG
Seq C2 exon
AGGAGATAGCAGATCTCACAGAACAAATTGCTGAAAATGGCAAAACCATCCATGAACTGGAGAAATCAAGAAAGCAGATTGAGCTGGAAAAGGCTGATATCCAGCTGGCTCTCGAGGAAGCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063:ENST00000583535:32
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.089 A=NA C2=0.286
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(6.4=100),PF045827=Reo_sigmaC=FE(37.7=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(4.8=100),PF045827=Reo_sigmaC=PD(24.0=83.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGTTGGCAGAGTGGAAGACA
R:
CTCTGCTTCCTCGAGAGCCAG
Band lengths:
291-592
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development