HsaINT0107909 @ hg19
Intron Retention
Gene
ENSG00000078814 | MYH7B
Description
myosin, heavy chain 7B, cardiac muscle, beta [Source:HGNC Symbol;Acc:15906]
Coordinates
chr20:33588571-33588961:+
Coord C1 exon
chr20:33588571-33588696
Coord A exon
chr20:33588697-33588790
Coord C2 exon
chr20:33588791-33588961
Length
94 bp
Sequences
Splice sites
5' ss Seq
GATGTGAGG
5' ss Score
4.17
3' ss Seq
CAGCTCCTCCTCCCCAACAGGCG
3' ss Score
7.85
Exon sequences
Seq C1 exon
AACACAGGCCTCCTAAACCAGAAGAAGAAGCTGGAGGCGGACTTGGCCCAGCTGAGCGGGGAGGTGGAGGAGGCTGCACAGGAGAGGCGGGAGGCTGAGGAGAAGGCCAAAAAGGCCATCACTGAT
Seq A exon
GTGAGGCTGGGCAAGGGCTGTGGGGAGCCTGGGACAGAATTGCAGAGGGACTTCCCTGAGGCTGGGCACCTGACCAGCTCCTCCTCCCCAACAG
Seq C2 exon
GCGGCCATGATGGCCGAGGAGCTGAAGAAGGAGCAGGACACAAGTGCACACCTGGAACGGATGAAGAAGACGCTGGAGCAGACGGTGCGCGAGCTCCAGGCCCGCCTTGAGGAGGCAGAACAGGCCGCCCTCCGTGGCGGGAAGAAGCAGGTGCAGAAGCTGGAGGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078814-MYH7B:NM_020884:40
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.905 A=NA C2=0.735
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(4.8=100),PF0003816=Filament=FE(15.6=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(6.5=100),PF0003816=Filament=FE(21.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACACAGGCCTCCTAAACCAGA
R:
TTCCAGGTGTGCACTTGTGTC
Band lengths:
182-276
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)