HsaINT0107910 @ hg19

Intron Retention

Gene

ENSG00000078814 | MYH7B

Description

myosin, heavy chain 7B, cardiac muscle, beta [Source:HGNC Symbol;Acc:15906]

Coordinates

chr20:33588791-33589152:+

Coord C1 exon

chr20:33588791-33588961

Coord A exon

chr20:33588962-33589047

Coord C2 exon

chr20:33589048-33589152

Length

86 bp

Sequences

Splice sites

5' ss Seq

AAGGTGTGT

5' ss Score

6.64

3' ss Seq

GGCTGTCCCCCTGCCTGCAGGTA

3' ss Score

10.83

Exon sequences

Seq C1 exon

GCGGCCATGATGGCCGAGGAGCTGAAGAAGGAGCAGGACACAAGTGCACACCTGGAACGGATGAAGAAGACGCTGGAGCAGACGGTGCGCGAGCTCCAGGCCCGCCTTGAGGAGGCAGAACAGGCCGCCCTCCGTGGCGGGAAGAAGCAGGTGCAGAAGCTGGAGGCCAAG

Seq A exon

GTGTGTGCAGCCCCTCTAGTCCTTGGCGCAGGCAGGGTGGGTGACCCAGGGGTGGGCTTGGCATCAGGCTGTCCCCCTGCCTGCAG

Seq C2 exon

GTACGGGAGCTGGAGGCTGAGCTTGATGCAGAGCAGAAGAAGCACGCCGAGGCCCTTAAGGGCGTGCGCAAGCATGAGCGCCGTGTCAAGGAGCTCGCATACCAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000078814-MYH7B:NM_020884:41

Average complexity

IR-S

Mappability confidence:

NA

Protein Impact

ORF disruption upon sequence inclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.735 A=NA C2=0.911

Domain overlap (PFAM):

C1:

PF0157614=Myosin_tail_1=FE(6.5=100),PF0003816=Filament=FE(21.3=100)

A:

NA

C2:

PF0157614=Myosin_tail_1=PU(31.5=97.1),PF096025=PhaP_Bmeg=PU(27.9=97.1),PF131661=AAA_13=PU(28.1=97.1),PF0003816=Filament=PU(31.2=97.1),PF060097=Laminin_II=PU(36.8=71.4),PF150701=GOLGA2L5=PU(22.5=71.4),PF117273=ISG65-75=PU(28.3=91.4),PF044267=Bul1_C=PU(27.2=71.4),PF150351=Rootletin=PU(2.6=5.7)

Main Inclusion Isoform:

NA

Main Skipping Isoform:

ENSP00000262873