HsaINT0107941 @ hg38
Intron Retention
Gene
ENSG00000133020 | MYH8
Description
myosin heavy chain 8 [Source:HGNC Symbol;Acc:HGNC:7578]
Coordinates
chr17:10418887-10420257:-
Coord C1 exon
chr17:10420018-10420257
Coord A exon
chr17:10419031-10420017
Coord C2 exon
chr17:10418887-10419030
Length
987 bp
Sequences
Splice sites
5' ss Seq
GCAGTAAGT
5' ss Score
9.07
3' ss Seq
GTTTCTTGCTTACTCACCAGACT
3' ss Score
5.48
Exon sequences
Seq C1 exon
GCAGAATCCTTTGCTAAATAAATCGCAGCCATGAGTGCGAGCTCAGACGCTGAGATGGCTGTTTTTGGCGAAGCTGCTCCCTACCTTCGAAAATCAGAAAAGGAGCGGATTGAGGCCCAAAACAAGCCGTTTGATGCTAAAACATCTGTCTTTGTGGCGGAGCCCAAGGAATCCTATGTGAAGAGCACTATACAAAGCAAAGAAGGAGGGAAAGTAACCGTAAAGACTGAAGGTGGAGCA
Seq A exon
GTAAGTGAAAACAGGGAGAAAATACTCCCCATTTTATTTCTTGGTTCAAAAGTTGAAGCCTAACTTACTGGGAATCTCCAAGCCTGTTGCCAATGCAAACACCCTTCTAGTCAGTGTTGAGACATTAGATGTGGAAGGCAAAAGAAATTCACAGCAGTACCTTCATGTCTTCCCTTCCCAACTTCGCACAGGACCTCACCCCACTATGTATGGCCTTCACCATTTCCCTTCAATTCCCCACTTCCTAGTCTGAATGTCCAAACTTGAGGGAAATGAAAACAAGCTCCTCCTATCAGAAGTTAAATATTTACTTAGTTAAATAATGTATTAATATCCCCATTACTTCCAAAAACATGAAGTTTCTTAATGAATGAAAGAAAAAAATAAAAATTTAGCCTACTAAAATAAGAAAAAAAGGATATAAACTGATAAATCTGGGATAAGAGAATGTGGGAGGAAAAAATCTTTTAAAAAGATAGTGTCCTAGCTCATCATAGGAAACAGGTTTTCTTAACATTAAACTCTGAAATGAATATATTTCATGCCTTTTTTAAGAGGACATTAAATAATATAATGAGAAGTATGTGTGATTATAGTTTTGTACCAAAATATACAGGCAAACATAAACCCTACCTCCAACCATTAAAACGAACTGGTCTTAGCCAGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGATCAGGAGTTCGAGACCAGCCTGGCCAACATGGCGAAATCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGATGGGCACTTGCAATCCCAGCTACTCAGAAGGCTGAGGCAGGACAATCACTTGAAGCAGGAGGGCGGAGGTTGCAGTGAGCTGAGATCGCGCCACTGCACTCCAGCCTGGGCAAAAAAAGCAAAACTCTATCTCAAACAAACAAACAAAAACGAACTGGTTTCTTGCTTACTCACCAG
Seq C2 exon
ACTCTAACTGTCAGGGAAGACCAAGTCTTCCCTATGAACCCTCCGAAATATGACAAAATTGAGGACATGGCCATGATGACTCATCTACACGAGCCTGGAGTGCTGTACAACCTCAAAGAGCGCTATGCAGCCTGGATGATCTAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133020:ENST00000403437:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.186 A=NA C2=0.062
Domain overlap (PFAM):
C1:
PF0273614=Myosin_N=PU(78.6=47.1)
A:
NA
C2:
PF0273614=Myosin_N=PD(16.7=14.6),PF0006316=Myosin_head=PU(4.1=58.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAAATCGCAGCCATGAGTGCG
R:
CTGCATAGCGCTCTTTGAGGT
Band lengths:
352-1339
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development