HsaINT0108177 @ hg19
Intron Retention
Gene
ENSG00000145555 | MYO10
Description
myosin X [Source:HGNC Symbol;Acc:7593]
Coordinates
chr5:16683989-16685940:-
Coord C1 exon
chr5:16685847-16685940
Coord A exon
chr5:16684045-16685846
Coord C2 exon
chr5:16683989-16684044
Length
1802 bp
Sequences
Splice sites
5' ss Seq
GTGGTACGG
5' ss Score
6.61
3' ss Seq
TACTTTTTGTTCTTTTCCAGGGC
3' ss Score
11.41
Exon sequences
Seq C1 exon
CCAGTGGTTCAGCGTGCTGAGTCAGGTCCACGCGTCCACGGACCAGGAGATCCAGGAGATGCATGATGAGCAGGCAAACCCACAGAATGCTGTG
Seq A exon
GTACGGGAGCACTGTGTGGGATGGGGGTGGGGCGTCTAGGGGCAGGGACGGGGAGGGCGTCAGGATGGTAAAAAAGGGAAAGATTGGGAATTTCCAGACAGTCTTTTTTTAAAAGGTAAATATAGAATAATTAAGGAGAAAAACAGGACCATTTGAGTTTAGAATCAATACAATAATAAATATAATAAGTGGTACAATATAATACAATAATAAATACAGTAAATTAAGTTGGACACTGTGGCTCATGCCTGTAGTCCCAGCACTTTGGGAGGCTGAGGTGGGAGGATCATTTGAGGCCAGGAGTTCAAGACCAACCTGAGAAACATAGCAAGACACTGCCTCTATGAAAAAAATTAAAAATTATCCAGGCATGGTATTATGGGCCTGTAGTCCCAGCTACTTGGCAGGCTGAGGCAGGAGGATTGCTTGAGCCTGAGAATTCGAGGCTACAGTGAGCTATGATTGCGCCACTGAACTCCAGCAGCCTGACCCTGTCTCCTAAAAAAACAAACAACAAAAACGAATAAATTACAGAAGGTTGTAAGTAGTAATACATTCCAGTTCTCTCACCTCAAACCTTTAAAAGAACAAAAGAAATAATCCTACTTTTTATGAAGTCACGGAAGTACACATCACACTTACTCTTCAGAGGACTTGGTGAAATCTAAATTGTATTCTTATTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCACCCAGGCTGAAGTGCAGTGGCGAGATCTCAGTTCACTGCAACCTCCGCCTCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCGCTTGCCGCCACACCCGGCTAATTTTTTGTATTTTAGTAGAAACAGGGTTTCACTATGTTGCCCAGTCTGGTCTGGAACTCCTGAGCTCAGGCAATCCACATGCCTCAGCCTCCCAAAGTGGTGATACAGGCGTGAACCACTGTGCTGGGCCGAAATCCAAATTGTATTCTTTGTCTTCCCTCTATCCCAGACACAAAGTTACAAAACCCTGCTTTGGAAACCAAGTTTTATTTCCTCATCAGAAAATCTTGAAATAAAGTTTCTTAGGAGAAGAAGTGTAAGATTTAATTAAAGGACACAATATAATCAGGAAATTTGTACTATTGAAAGAAGGTCATAAACACTGTTCACTGAACATATTTTAAGAATAAGAGGGGCCAGGTGCGGAAGCTCAGACCTGTAATCCCAATACTTTGGGAGGCCAAGGCGGATGGATCACTTGAGGCCGCCAGGAATTTGAGACCAGCCTGGCCAACATGGCGAGACCCCATCTCTACTAAAACACAAAATTATCCAGGTGTGGTGGCCCACACCTGTAGTCCTAGCTACTTAGGAGGCTGAGGCACGAGAATCACTTGAACCTGGAAGGCAGAGGTTGCGTTGAGCTGAGATCACACCATTGCGCAGCCTGGGCAACAGAGTGAAACTCTGTTTCAAAAACAAACAAATTAAATTAAAATAGAGGTACTTGTAGAAAACTTAGTTAAAATATTTTTAAAAACAAAGAAATAAATTATTGAAAGGTTAAGAGGTAATGATTAACTTGTAATTTTAAAAAATAAATGGCCTATAGATTCTGCTCCGTGTAGAGGCTATTTGTACTCACACAACAGAGGAGTCGTCTCATAGATAACTATTATTTTGAAGTTAAAAAGAAAAGAGCCTTTTCTGTCTGATTGGGAGTTGTGGGCTAGAGGTATTACTGTAGTGTGCACCCTACTTTAGTGCTTCTCTCATTCTGTTTACTTTTTGTTCTTTTCCAG
Seq C2 exon
GGCACCTTGGATGTGGGGCTGATTGATTCTGTGTGTGCCTCTGACAGCCCTGATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145555-MYO10:NM_012334:29
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.500 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0016924=PH=PD(11.2=34.4),PF0016924=PH=PU(25.0=56.2)
A:
NA
C2:
PF0016924=PH=FE(25.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)