HsaINT0108630 @ hg19
Intron Retention
Gene
ENSG00000136286 | MYO1G
Description
myosin IG [Source:HGNC Symbol;Acc:13880]
Coordinates
chr7:45016462-45018704:-
Coord C1 exon
chr7:45018466-45018704
Coord A exon
chr7:45016671-45018465
Coord C2 exon
chr7:45016462-45016670
Length
1795 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGGC
5' ss Score
9.88
3' ss Seq
CCTACCCCTGCTGTGTCCAGGTT
3' ss Score
7.77
Exon sequences
Seq C1 exon
ACTTCCTACTTTACACCAGCACTGGAGGAGGCTGGTGGGGCAGGGCGGGGGCGGTGGGGCCTCCCCTAGCCTTCCCTCCCCCTCTCCTTCACTGTCCTTCCAGCAGGCACAGGAAGGTGAGGCAAGGTGTTTCCAGCCGGCAGGATGGAGGACGAGGAAGGCCCTGAGTATGGCAAACCTGACTTTGTGCTTTTGGACCAAGTGACCATGGAGGACTTCATGAGGAACCTGCAGCTCAG
Seq A exon
GTAGGCCCAGGGCAGGAGGCAGTGGCTCCCCTCCTCCAGGGTCTCCCACCTTGCGTCCTCGCAGAGACCTGAGGGAAAGAGGAAGGCACGCTGCTGTCCAAGGGAGGGGGCAGTGGCACACACCCACCCAGACCAGATGGGGCTGAAATGAGTGCCTCAAAGCACGGCCCCAGGGGACAGGAACAGACAAGGAGGCAACTGTCCCTGTCAGGGCTGGCAAGTCAGCACCGGAGCTGCCCACCACCTCAACCCACCCCTGCCTCCCACACAGTCCAGGCATCTTCTGCCCCTTCTTTCCTGCCCGACGGGGCCAGGGCATGACACTTCTTGGACAGATACATACCAGGCACTATCTTTCCAGGAGGGACCAGGGGCACCTCCCTCCAGCCACTTCCCAGCCAGTTGTTGATGCTCCCTCGATGCATCTCATCCATGGGGCCTGGCCTGAGCCCTGGGGACACTGAGATGAAGCAGTCAGGCTCCACCCTAGGGTCCAAACATTCCCACCAAGTTGAGGTGACATTCTCCTGGGGTACATGGAGTATCACAGGACACAGTTGGTAGAAGTGATATTGGAGCCCAATTTACCATCAAGGAGGGCAGGTGGAGGGCAGGGAGAAGCCCGGGAGGTAGGGGCATGGCACAGTAGGGTGGCCATACAGGCAGCTGGGCTTCCTGCCAGGACTCCCAGGGAGGGGCAGAAGGCCACTCGCTGTGTACTCCGGAAGCTCCCTGGGGAGAGCTTGGGGACCAGGATCCCCACTAAGCACCGAAGGCAAGAGACCACGAGCCTGGCTCAAAGAGGAGGGCTAGCCAGGACGTGAGCTAAGCACTTTGTGCACATTGTTCTACCTCATTCTTATAAAATGAGCTTATGAAACATTGTCCTCTCTATTTTGATGAGGAGAACACTGAGCCCTGGAGACGTGGGTGACTTGTGCCCTCATCCCCAGCTTGTAGGAGGATGGGAGCTAGGCCCAGGAAAACCCATGTCAGAGGTGGTGGAGAAAGAGGAACCTCAGGACAGGCCCACCCAGGACAGGCTGCCGGGAGACAGGGCCATCCAGGGAAGGGTGGGTACCACACACCAAGGGGAGATGGGTCTGAGGGGCAGGCCTGCCAGTCCTCCTCCCAGGGGCAGAAAGGTCAAGAGAAGGGCAGACATCCACCCCCACTGGGGACCAGGTTTGTGAAGGAAAGGGTCAAGAAGTCTGAGGCTGTGCCAGGGGAGAGGCAGCAGCCACTGGCCACAGGCTGGGGGGTCGGGGGTGTAAAGACAACGACATCAACTCCCTCCCTGTCATCTGGGTGGGGCTGGGTGGGGTCCCCTTTTGTCTCTGGGTTCCCGCCCAGGCCTTGAGACAGGAAACAGCCGAGGAGGCCCCTCCTTCCCCTCCCAGCCCAGTCACTTCTCAACCCCATCTCCCCATCTGCCCTGCGGGGTTCACCCCAGGAGCCAGCCCTGACTCACGGCACCCAGTGCAGTCTTGGGCAAGTCTGTTTCCTTTGCAAAATGAGTGGTCATGTTTCCAGTGACCTTGGGATCCCTGGGGAGACCACTGTGGACCCCAAACTCTATGCCGCAATGGAGACAGTCTCTGAGTGGCTCAGCTCACCCAGGATGGCACCAGGGAGACGCAAGGTCAACACCTGCCCCCTTCTTCCTTCTCCACTCTCAGCCCGTCAGGGTGGGAGCGCTGGCCTACTGGGGCCAGGCCCTGATATGGGCTCTGGCGAAAGGCCTGTGGGTGCCTGTAAGCCTGTGAGTGCTGAGGCCTACCCCTGCTGTGTCCAG
Seq C2 exon
GTTCGAGAAGGGCCGCATCTACACCTACATCGGTGAGGTGCTGGTGTCCGTGAACCCCTACCAGGAGCTGCCCCTGTATGGGCCTGAGGCCATCGCCAGGTACCAGGGCCGTGAGCTCTATGAGCGGCCACCCCATCTCTATGCTGTGGCCAACGCCGCCTACAAGGCAATGAAGCACCGGTCCAGGGACACCTGCATCGTCATCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136286-MYO1G:NM_033054:1
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.242 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PU(11.4=65.6)
A:
NA
C2:
PF0006316=Myosin_head=FE(38.0=100),PF139341=ELYS=PU(9.0=9.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCCTCTCCTTCACTGTCCTT
R:
CCGGTGCTTCATTGCCTTGTA
Band lengths:
342-2137
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)