HsaINT0108750 @ hg19
Intron Retention
Gene
ENSG00000071909 | MYO3B
Description
myosin IIIB [Source:HGNC Symbol;Acc:15576]
Coordinates
chr2:171356156-171358375:+
Coord C1 exon
chr2:171356156-171356318
Coord A exon
chr2:171356319-171358294
Coord C2 exon
chr2:171358295-171358375
Length
1976 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAT
5' ss Score
8.76
3' ss Seq
ACATGGTTTTATATTTTTAGCCT
3' ss Score
6.06
Exon sequences
Seq C1 exon
GTTTTTCTCAAATATTACCATGTTGAGCAATTAAATTTGCTGCTTCGAGAAGTCATAGGCAGAGTGGTTGTGCTGCAGGCATATACCAAGGGGTGGCTTGGAGCCAGGAGATACAAAAGGGTCAGAGAGAAGAGAGAGAAGGGAGCCATTGCCATCCAGTCAG
Seq A exon
GTAAATGGTCCTGTTCTCATAAATACTGCCCTGGGTATTGGCATGTCATTAAGTACTGGGGAATACTCAACTGTTTCTCTTCTAAGTGGTTTCCCTCCCTCCCTTCCTTCTCCCCTCCCTCCCTCCCTTCCTTCCTTCCTTCTTTCCTTCCTTCCTTCCTTCTTTCCTTCCTTCCTTTAGCAAATGTGTATCAAATGTGTATCAAGTGCCTACTACACAGGTTCTGTGCCAGGTGCTGAAATCACAGCCATGAGCAAGACTGTGTAGGGGTGAAAGAAACTTTCTTTCCGTGTCCTGAAGATTTGATAATTTGAGTCTATAAAACAAACTGAGAAAGACAGGTTAACAGGAGAAAAGACATACAAATTTATTAACATGCAAGTCATAAAAAGTGTGAAACTCAAAGGCCAGATGGTTGAAGCTTAAATACCCTCTTCATAGGGGAGAGGGAAGTGGAGGATGTAGATAGTTTTAAGGGAAGATTCAAAGGTTTACGAGGGAAATGAATGGGCCTAAGGAACAGGCAATAGCCTGGGACAAAGTTCATCTGACCTCTGGGTGATATTTACTCCAGTCTTTCTTCCTGGGGTATGCATCAGTTTCTCCTGGTTGAGGAGATATCTGGGGAAGGGATTCACACAGTTGAATATCTTCTGGAGGAGTTTGCCTTTAATAGATAGGGAGAGTTCAGAGAAAGCCCTTCCCTGCATTTGCTGCTACCCAGGTGCTCTAAGTTTGAAGTCAAAGCAGCATATTTTGGAGAATTATTATCTGAGCCCCAACAACTGCCATGGTCCCTGACTTGCAGGTAAGCAAACAAGTCTTTACAACATGAGTGACAGGATAGATAGTGGCGGTATAAATGGACCAGTGATGTAAAGCCCCAGTCACACAGATATGTGCCGCATCTCCCAGAATGACTGAGATAATATACACTTCAGGTCTGTGGTCAGGTGTTCAGTACCAGAGTTACTAACGCCATTTCCAGAAGGCTTTTCTAGTCCAGATGGAACTTATAAACCAAGGGAAGAGGTTGCTAATCTCTTTCATGTGCCCTGCCTAGTCAGTGCCTCTTTGTTTACGTATATGTGTTATTAGTGTTACACACAACATTTAAGTTCCTGTGCAATAGACAAATGATTATGAAAGCACCAGATCTTGAACAAAGTGGATGATTTCCCTTATGCTCTCATAACCCAGAATCCTCATGTGGCTCAGTCTATTTTGGACTTCATGAGCTCACCCAGCAACTTCGAGAGTTGTGATGCTGAGACGGGAGGAACAAAGACATTATGCTCCTCGTGGGTGGCTTAATGCCCCAGTTTTGTATCTAAAGGGCTTACCACCTTTGCCCCAGAGAGTCCCTTCCTCTTTTCTCTCTTTTTCTTCACCTTTCTTCCCTGCCTTTTCCCTTCCCACTGCACATCTTTCCTCTCCCTCAGCATACCTCTCGGCACAGAATTCACTCACAGCAAATGACAGTGTTGTGCTACTTATCATTTCCCTTAACTCCGCTCTTTCTCTTCTTCAACTTTCCTGTTTATATTTTTCTCCCAAATAACAGATTTTGAAAGGGTCAGGCTATTCCAGTTCCTTTCTACCATCCCTGCCAAACCCTTCCACCTGTATCATATCCCCGAGTCTTGAAGACAGGGCTTTCTCCAGGGATTAGAATGACAGGAAACCATCTCACCTGGAGTAGGGGTCCCATGTGATTCATCAGTGGAACCCAGAGTGTTCTGGAAATCACTGCCTGAACAAAAGCAACCCCTCAGAAGCATCTTTAAAGCCAAGCTGTGAGAACAGAGAGGCCTCTCTTCTCGCCATAGATCACATACCTCTGCTTATTTTGTTCAGTGAGAAAGCAGGAGGGAGGATGAGACGGGCAATAGGCTGGAGGGGAAAACAGCTTATATCAATTCTCTGGCACGTTCTTAAATTAATGTCATTCCTAGCACATGGTTTTATATTTTTAG
Seq C2 exon
CCTGGAGAGGATATGATGCTCGGAGGAAATTTAAGAAAATAAGCAACAGAAGGAATGAGTCTGCTGCTCATAATCAAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000071909-MYO3B:NM_138995:27
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.047 A=NA C2=0.571
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PD(0.4=5.5),PF072198=HemY_N=PU(85.2=83.6)
A:
NA
C2:
PF0061222=IQ=PD(52.4=39.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTCAAATATTACCATGTTGAGCAA
R:
TGCTTGATTATGAGCAGCAGACT
Band lengths:
238-2214
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)