HsaINT0108916 @ hg19
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:7606]
Coordinates
chr11:76915121-76916662:+
Coord C1 exon
chr11:76915121-76915274
Coord A exon
chr11:76915275-76916506
Coord C2 exon
chr11:76916507-76916662
Length
1232 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
3' ss Seq
GCCCACGCCTCCTCCTGCAGGTA
3' ss Score
10.17
Exon sequences
Seq C1 exon
CTGTGCTCAAGTACATGGGCGACTACCCGTCCAAGAGGACACGCTCCGTCAACGAGCTCACCGACCAGATCTTTGAGGGTCCCCTGAAAGCCGAGCCCCTGAAGGACGAGGCATATGTGCAGATCCTGAAGCAGCTGACCGACAACCACATCAG
Seq A exon
GTGAGCCAGGCACAGTGGGCGGATGAGGGGCAGACCTCACCTGCTGTGACGGGCAGCTCTTACCCTCCTGAGGCAGCTGCTGGCTCTGCCTGGATGCAGTCCTTCCTCACACAGAGCCGGGAGCTGCTCATGGGCCCCCTCACATCCTAGCTTGGCCCCAACGCCCAAGGAGGGCCTAGCAGGAACTGGGAGGTGGTGGATGTCTTCCTTTGAGTCTGTCCTCTAAGGGTAACAGCCCCAGCTCCTCCTAACGTTTGGCTGGAGCCTCGTCTGGATGCCCCTTCCCTGCCTAGACCCTGCTGTCTGCCTGCAGGTCCAGCTCAGTCAAGTGTCCCCTCCCTGGTGCAGGCTGGGCCGGCTGTCAGCTGGAAGCACTGGCTGAAAACTCTCATGGGTTTGAGTGTTGGTCCCAATGCCCAAAGGGTGCCACCTTCTCCTCCCGCTGGGACAGCCCAAGACAGGAGTAGAAAGTCAGGCACAGGCTCCTCTCAGAGTCTGAGAGAAGCTCCACCCTCTCTCCTTACACCCAGCCCCCCGCCTTCCTCCCCAGCTGTGTCACCCTCTACATCTCTTCCACAAATCCATCCTCAAACTACACATCAGCTCTTTTGACAGTGCCAAACCTTTGTACATACTGTGCCCACAGCCAGGAAAACTTTTCAGCCCCTTCTCTGCATGCCGTAATTTGCTTCATCCTTCAAAGCCTAGTTCAAATGCCACCTCCTCCTAGAAGCCCTCCAAACTTCCCACTGTCAGGCCCAAGAAGCTCAGAGTGGTGGCTGAAGGAGCCTGGGGTGGGACTGGTCTAACTCGTTGCCACTCAAAGTAGAGGTGAATTAAAGAGCTTCTGCGAAAATATAAATCACACTGCTTCCTTCATGGAGAAAGTCTTGCTATGGAAACAAACAAAAAGCCTCAGCTGAAGCAGAGTGCATGGTAACCCGGTGGCTTTTCATTGTGGCATAAGCCCCTTATCTCCACGTGGACTGGTAGCAGTGTGTGGCCTGGCGCGGTGGGCCAGGCACACTTTGGGTAGCACTAGTTGCATCTGGCTGTCAGGGAGAGGGGTCTGTAGGTAGGGTGAGGGGTCCTGAGATAGGGTAAAGGTCAGGAGGGACGGTGCTGCTGTGATGAGCAGCTGAGGGGTACATGGCCCCCTCACCCGGGGGTGCACAGGTCCTGTGACTCCCGATGGCAGCTGCCCCTGCTGGAGCCCACGCCTCCTCCTGCAG
Seq C2 exon
GTACAGCGAGGAGCGGGGTTGGGAGCTGCTCTGGCTGTGCACGGGCCTTTTCCCACCCAGCAACATCCTCCTGCCCCACGTGCAGCGCTTCCTGCAGTCCCGAAAGCACTGCCCACTCGCCATCGACTGCCTGCAACGGCTCCAGAAAGCCCTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474-MYO7A:NM_000260:39
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0078412=MyTH4=PU(34.6=71.2)
A:
NA
C2:
PF0078412=MyTH4=FE(48.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTCAAGTACATGGGCGACTAC
R:
CTCAGGGCTTTCTGGAGC
Band lengths:
306-1538
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)