HsaINT0108916 @ hg38
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:HGNC:7606]
Coordinates
chr11:77204076-77205617:+
Coord C1 exon
chr11:77204076-77204229
Coord A exon
chr11:77204230-77205461
Coord C2 exon
chr11:77205462-77205617
Length
1232 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
3' ss Seq
GCCCACGCCTCCTCCTGCAGGTA
3' ss Score
10.17
Exon sequences
Seq C1 exon
CTGTGCTCAAGTACATGGGCGACTACCCGTCCAAGAGGACACGCTCCGTCAACGAGCTCACCGACCAGATCTTTGAGGGTCCCCTGAAAGCCGAGCCCCTGAAGGACGAGGCATATGTGCAGATCCTGAAGCAGCTGACCGACAACCACATCAG
Seq A exon
GTGAGCCAGGCACAGTGGGCGGATGAGGGGCAGACCTCACCTGCTGTGACGGGCAGCTCTTACCCTCCTGAGGCAGCTGCTGGCTCTGCCTGGATGCAGTCCTTCCTCACACAGAGCCGGGAGCTGCTCATGGGCCCCCTCACATCCTAGCTTGGCCCCAACGCCCAAGGAGGGCCTAGCAGGAACTGGGAGGTGGTGGATGTCTTCCTTTGAGTCTGTCCTCTAAGGGTAACAGCCCCAGCTCCTCCTAACGTTTGGCTGGAGCCTCGTCTGGATGCCCCTTCCCTGCCTAGACCCTGCTGTCTGCCTGCAGGTCCAGCTCAGTCAAGTGTCCCCTCCCTGGTGCAGGCTGGGCCGGCTGTCAGCTGGAAGCACTGGCTGAAAACTCTCATGGGTTTGAGTGTTGGTCCCAATGCCCAAAGGGTGCCACCTTCTCCTCCCGCTGGGACAGCCCAAGACAGGAGTAGAAAGTCAGGCACAGGCTCCTCTCAGAGTCTGAGAGAAGCTCCACCCTCTCTCCTTACACCCAGCCCCCCGCCTTCCTCCCCAGCTGTGTCACCCTCTACATCTCTTCCACAAATCCATCCTCAAACTACACATCAGCTCTTTTGACAGTGCCAAACCTTTGTACATACTGTGCCCACAGCCAGGAAAACTTTTCAGCCCCTTCTCTGCATGCCGTAATTTGCTTCATCCTTCAAAGCCTAGTTCAAATGCCACCTCCTCCTAGAAGCCCTCCAAACTTCCCACTGTCAGGCCCAAGAAGCTCAGAGTGGTGGCTGAAGGAGCCTGGGGTGGGACTGGTCTAACTCGTTGCCACTCAAAGTAGAGGTGAATTAAAGAGCTTCTGCGAAAATATAAATCACACTGCTTCCTTCATGGAGAAAGTCTTGCTATGGAAACAAACAAAAAGCCTCAGCTGAAGCAGAGTGCATGGTAACCCGGTGGCTTTTCATTGTGGCATAAGCCCCTTATCTCCACGTGGACTGGTAGCAGTGTGTGGCCTGGCGCGGTGGGCCAGGCACACTTTGGGTAGCACTAGTTGCATCTGGCTGTCAGGGAGAGGGGTCTGTAGGTAGGGTGAGGGGTCCTGAGATAGGGTAAAGGTCAGGAGGGACGGTGCTGCTGTGATGAGCAGCTGAGGGGTACATGGCCCCCTCACCCGGGGGTGCACAGGTCCTGTGACTCCCGATGGCAGCTGCCCCTGCTGGAGCCCACGCCTCCTCCTGCAG
Seq C2 exon
GTACAGCGAGGAGCGGGGTTGGGAGCTGCTCTGGCTGTGCACGGGCCTTTTCCCACCCAGCAACATCCTCCTGCCCCACGTGCAGCGCTTCCTGCAGTCCCGAAAGCACTGCCCACTCGCCATCGACTGCCTGCAACGGCTCCAGAAAGCCCTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474:ENST00000409709:39
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0078412=MyTH4=PU(34.6=71.2)
A:
NA
C2:
PF0078412=MyTH4=FE(48.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTCAAGTACATGGGCGACTAC
R:
CTCAGGGCTTTCTGGAGC
Band lengths:
306-1538
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development