HsaINT0108918 @ hg38
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:HGNC:7606]
Coordinates
chr11:77206097-77207402:+
Coord C1 exon
chr11:77206097-77206202
Coord A exon
chr11:77206203-77207288
Coord C2 exon
chr11:77207289-77207402
Length
1086 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGG
5' ss Score
8.41
3' ss Seq
GTGCTCACTGCCCCTCCCAGGCC
3' ss Score
6.71
Exon sequences
Seq C1 exon
AAACGGGTCCCGGAAGTACCCTCCGCACCTGGTGGAGGTGGAGGCCATCCAGCACAAGACCACCCAGATTTTCCACAAAGTCTACTTCCCTGATGACACTGACGAG
Seq A exon
GTGAGGGTCACCGGCTTCTAGGTCTGCAGTGCCCAGGACAGGGCCGGGCTTCCTGGGTGGACACCAAAGGTGGCCTTAAGCCTCTCCCCCATCACCTGACATTTGCCGCCTCGTCCTCCTGCCCCGTAGTGGAGTCGGGGCTCAGGACGAAGGCCATCGACTCCCCAGGTCAGGGGCCCTTGGTTCCTGATCCAACCCCTGCTTCCTGGAGCAGCTTCCTTCAGAAGGGCGCCCCTCCCTCCCTGTCTCTGAGGAGGACTTGCCTTGGAGAAAAGCGCTTCTCCCTCTGAGCTGGCTTTGCACTGGCTTTGCACCTCCCTGATGTAGGGCCCCACTGGCCCCCAGGTCCAGACCTCCCCTGTCGACTGAGCCCACTTTCCTGCAGGCAGAACCTCAACACCCCTTCCTCCCTCTCCACCTGAGGTGGTTGAGGTTCCCTCCATCCAGGTCCTGTCTGCCAAAGGTCCTGTCTGTCATGCCTGTAGTCACGCTGCCCCTCATGGTCCCCAGCCCCTGCCTGTCTCAACACAGTGTCTCATTCAGATAAGCTTTTCATTTGAAGAGTCATTTATGAAACTTGTCTGAGGCTGGAGACTCAGAAATGCCATAACAGGATTTCATTTGCAAGGACCAAAGACTTCCTCAAATCCTTTCCTGTCCCTCCAGACATCTCTCCTGCCATTAAACTTCCCCAGACGCTCAAACCCTCCCATCTGTCCGGGCTGCTTTCCCCTCCGCTTTTGGGTTTGCTTTTCCTCTACCTCAAGTCTCCTCCTTCTAATCACCCTTCCAGTCATCCTGCTGTGCTCCCTGGACCCCTCACTGTCACTCAGGCTTGTACACCCTGGCCCAGGACTCTGGACGCCAAGGCCACCTTCTGCTTGGAGAGTCGGGAGGAGGAGACCTGGGAAGACCCAGACAGGAGTAGCCCTTTCCTTTTGTTAAATGCCATGCCCAGCTCTGTGCCCACAGGAGGGTGTCTGGCACGGGAGGGGGCTCAGTATAGGAGGCATAGCCAGAGGGGCCCGGGAGGACCAGGTCCCGGGAAAGGCCCTGCAGGAGCCCAGTGCTCACTGCCCCTCCCAG
Seq C2 exon
GCCTTCGAAGTGGAGTCCAGCACCAAGGCCAAGGACTTCTGCCAGAACATCGCCACCAGGCTGCTCCTCAAGTCCTCAGAGGGATTCAGCCTCTTTGTCAAAATTGCAGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474:ENST00000409709:41
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0078412=MyTH4=PD(15.9=47.2),PF093795=FERM_N=PU(8.5=22.2)
A:
NA
C2:
PF093795=FERM_N=FE(39.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGTCCCGGAAGTACCCTC
R:
TGTCTGCAATTTTGACAAAGAGGC
Band lengths:
214-1300
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development