HsaINT0108982 @ hg38
Intron Retention
Gene
ENSG00000169994 | MYO7B
Description
myosin VIIB [Source:HGNC Symbol;Acc:HGNC:7607]
Coordinates
chr2:127565233-127566827:+
Coord C1 exon
chr2:127565233-127565385
Coord A exon
chr2:127565386-127566642
Coord C2 exon
chr2:127566643-127566827
Length
1257 bp
Sequences
Splice sites
5' ss Seq
TATGTGAGT
5' ss Score
5.56
3' ss Seq
ACCACCTGCTTCCTTCCCAGACA
3' ss Score
9.55
Exon sequences
Seq C1 exon
GAACACTGGATCCGAGCAGAGGACTTTGGTGTCCTCAGTCCCATGCACCCCAACTCAGTCCAGGGTGTGGACGACATGATCCGCCTGGGGGACCTGAACGAGGCAGGCATGGTGCACAACCTCCTGATCCGCTACCAGCAGCACAAGATCTAT
Seq A exon
GTGAGTCTCCCCAGCCCTGTGTCCACAGGGGAGCCCCTCACAGGTGCCAACCTCCTGGACAGGGAGAAGAAAATGATGCACAGGGGGCACTGCCCCCCATGCCCTCACTGAGGGAGGTGGGCGAGGTGCCTAACTTTTCCCAATCTCTGCTGCCCAGTCCCAAACAAGGAGGGTGATCCCACCCTGGAGGGGAGGAAGCCAATGCGTAGAGTGACAGCACAGTGCCTGGCACAGTCTCTGCTCAGTGAGGGCTGCAGATGGCCATCAGGTGGCCATCATCCTCTGCCCTCTCCTTCCCAGGCATGTTGTAGAGACAGAGTCACTAGACAGAAAGCCCCTGGCCTCCCAAGAGTGAGGCCCGTGACAGCCCAGATCCCAAGGTCCTGATTCACCAGACGAGGGGGCCATGGGGATGGATGTGGGCCCTCCGTGCAAACCTGGCCTGGATGGAGGTTCACTCCAGCCTGAAGCTCTCATCCTGGTTCCAATGCAGATTTTTCCAGGGGAGGTGGTATTCCAAAACCGACACCAGTTCGGCCTAAGTAGGTGTGGCCTGCAGAAGCCACTGCCTGCCTGGGCCTCTCTGGTCTGGAGGGGTGGCTAGCTTGGTTCTGACTGGCCCTTCTGGGCTGCTCAGAGGAAAGCAGCTTGTGCTTCCAAAGGGCTTTTGCCTGCACTCCTCATCTGGTGGCACAGCCTGAAGCCAGAGGGCACGTCCTCTCCTTTCCTAAAGTGAAAACCAGGACACCATGGTCATGTGGCTTATTGTGCAGGCTCTGCCTGCCGCACCCCCTGAGGGGCAGTGGGGCTGGGTGGGGGCTCCAGATGGGCAGCTGATCCAGGGCGGAGGTCCCAGGGGCACACAGAATTTGGGGTTGGGGTCCGTGAGGCCCAGTTGTTGACCAGCCTATATGAAAGCCCCTGCGGGATGCAGGTGAAAACCCATTTCATACTTAGTCCATTTTTATCGAGCCCCTTCTAAATACCAGGCAGGGTACAAAACAGTTAACATTTGATCTTCCTGGAAATATGTTCCCTGGGAGCTCACCTTCCTGGTGGATATCCCATCTTCCCAGAGGAGAGATCTGCGCAGCTGAATGTCTGATCTCCCTGGCCCAGAATCAGATTCTACTTCCCCACCAAAGTCAGTGGCCCTGATAACCCCGAGGGCAGAGCCAGAGCCAAGGCCAAGGCCAAGGCCAGGGCCGAGTACCTCTGCCAGGGGCAGAGGGCACTGACCACCTGCTTCCTTCCCAG
Seq C2 exon
ACATACACAGGCTCCATCCTGGTGGCCGTCAACCCGTTCCAGGTGCTGCCGCTCTACACCCTGGAGCAGGTACAGCTCTACTACAGCCGCCATATGGGCGAGCTGCCCCCGCATGTCTTTGCCATCGCCAACAACTGCTACTTCAGCATGAAGAGGAACAAGAGGGACCAGTGCTGCATCATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169994:ENST00000409816:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PU(4.1=54.9)
A:
NA
C2:
PF0006316=Myosin_head=FE(8.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAACACTGGATCCGAGCAGAG
R:
CTGATGATGCAGCACTGGTCC
Band lengths:
338-1595
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development