HsaINT0112845 @ hg38
Intron Retention
Gene
ENSG00000162614 | NEXN
Description
nexilin F-actin binding protein [Source:HGNC Symbol;Acc:HGNC:29557]
Coordinates
chr1:77916055-77917757:+
Coord C1 exon
chr1:77916055-77916133
Coord A exon
chr1:77916134-77917565
Coord C2 exon
chr1:77917566-77917757
Length
1432 bp
Sequences
Splice sites
5' ss Seq
GAGGTAAGT
5' ss Score
11.08
3' ss Seq
TTTATTTTCTTCTAATGAAGATT
3' ss Score
5.19
Exon sequences
Seq C1 exon
GTGCAAATATATACAGAGCTTCATAATCAGCCCAAGACCACATAGAGCAAACATGAATGATATTTCCCAAAAGGCTGAG
Seq A exon
GTAAGTCTCAAAAGTAAAAATAAAAATAAAAGAGGGAAATGTAGAGTTGACTGTAGAATTGCTGAAAGGACAGTCATTTGGTGGAAAGGTCATATTTAGGAGTTCATAATTAATAACATAATGGCAAGATGTAAAACAAGAAGAGATACAATTCACCAGCTGGTCTTGGGCTAGTATTTTCATTTGGGTTCTAGGAAATTCTACAAAGCATGAGTAGTAAATTTGTGAATGATAGTGAAGTGGATGTGATAGCTAGCATTCTGAGTAGAATTTTAAATATTTTGTTCTTGATAACTCTTAGAAATTATTATTTTAGTATTAAAACAAAGTTTGACCTATACTCATAGGAGAAAACATAATTCCCTCTTAGGTAAGGAACCTTTTTAGTGCCTTATATATATATTTTAATTTTTAGCTTTCTTCTGGTTCTTGACTGTAGATACTGAGAGTTGTAAGAAGAGCTCAGTTGCTGACACCTCAGAATTATAAAGTTAACCCTTAAATGGCCAATGACACATAATAGATTATAAAATACAAGTTGGATGTGCCACAAATTAATTAAGTAATTGTCATTATCACTAGGAAAAAGGATTTGGTGTTCTGAGGCACACATTTTATTTACTGAAATTTCATTTAGAAATCAGCTTAATTTTCAAAGTGGTGAAAATAATTTGCTCTTCTGGTTTTAGAGTGGAGGAAAATCATTTCTTCAGTCTTCTACCAGATTCCCATTCTTTGTGAAGCTGTTGCCATATGGAATTCCTCTTACAGCCCGCCCCCATATAGAATGATATAGCCTTCTTACACATTTTTAATGTGGCTTAAAGAAGTTATAGATGGGAAGTAATAGTAACAACATAAATCACAGCTTGTGCACACAGACCACGGTGTACCTCAGCCACAAATAAGGACTAAAGGACTGGCCTTTGGTTTTGCTTATATTGGATATAGAAACCAGGAAGGGGGTAAAATGTGAATTAGGCTCAAACTTTAAAGCCTAAACTTTTGCTTTGTTTTCAACTTCACCAAATTTACTGAAATTAGTTTGGGTACTTTTTTAGCAAGTGATATCAAATCTGAATCTTTAATAATGGAGTTAGACAATAAAAGACAGTTGTTTTTAATTAGAATTCAGAATTTGATTTTTATATTTTACTGGCTTTCAGCTTCAGTGGAATGCTACCCACAAAATGAGATTTCATTACTATATAACAGTGAAATTTCTACTCTCATATTTTCTGTAATGTCATTTTTCATAGTTAGGTTTTAGAAAGTATCTAATCAGGTTGTGATGGTCAAATAAAGGGTTCAAACACATTTCTATTTTCTGTTTCAATAAATATTTTTTATATTGCTTATTCTTATCTATCTTTACCTAATTTCTTCCTATCTTTTTCGTTAACTTTCTTTTTTTTATTTTCTTCTAATGAAG
Seq C2 exon
ATTCTGCTTTCTTCATCTAAACCTGTCCCAAAAACCTATGTACCAAAACTTGGCAAGGGTGATGTAAAGGATAAGTTTGAAGCCATGCAGAGAGCCAGGGAAGAAAGAAATCAAAGGAGATCTAGAGACGAAAAACAAAGAAGAAAAGAACAATATATTAGAGAGAGAGAATGGAACAGGAGAAAGCAGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162614:ENST00000334785:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.867 A=NA C2=0.927
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TATACAGAGCTTCATAATCAGCCCA
R:
CTCCTGCTTTCTCCTGTTCCA
Band lengths:
262-1694
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development