HsaINT0115706 @ hg38
Intron Retention
Gene
ENSG00000197893 | NRAP
Description
nebulin related anchoring protein [Source:HGNC Symbol;Acc:HGNC:7988]
Coordinates
chr10:113623529-113624930:-
Coord C1 exon
chr10:113624826-113624930
Coord A exon
chr10:113623637-113624825
Coord C2 exon
chr10:113623529-113623636
Length
1189 bp
Sequences
Splice sites
5' ss Seq
GAGGTACAG
5' ss Score
6.62
3' ss Seq
TCTCTCCTAAATCCCCTTAGAAA
3' ss Score
7.67
Exon sequences
Seq C1 exon
GTGGCCTACAAGGCAGGAAATGAGCAGTCTGTCCATCAGTATACCATCAGCAAAGACGAGCCTCTCTTCCTGCAGGCCCGAGCCAATGCTGCAAATCTCAGCGAG
Seq A exon
GTACAGAGAGAATGAGTGGGCAGCAAGAACTCTGCTCCCCTTTGTGTATAGCCACCTGGTAAACCAAGCCCACCAGCCATGGCATAGTGTCTGTATCAACTGAGGTTACATACATCTGGTTGTTGTAAAAACAGCTCACCCAGCAGATCTGGCTCCTGATCAGTGTTTTAGGGGGAGAGGAGGACAGCTTTCATAGGAATGAGCTAGTGGAGGACTTGAGCTGCTGATTGTATCCTGGGGTTGGAGGTAGGGGTTATTCTAGGTGCCAGAGTTGAAACAGCATAATCGTGTTAGAGGGGAGTAAGAGCTCAGACATTTGCTCCAAATGGTCTGGGTTTGATCCTCGGTTGCCACTTACTAGGTGTGTGACCTTGGGCAAATTCTTTGTTTCCAGGTGTCCCATTGGTAAAATGATACCAATATTAGTCCCGTCCTTACTGGGTTGTCATGAGGTTTCAGTGAGTCTCTATACATCAAGCACTCAGAGGCAAGTGCACAGTGGTAGCTGTTAGTCATGAAAGCATCCATAGTTCCAACTTCCCCTTCTCTGTATCTTCTGGGGAAAGTGTTTTCTTGGCTCTCCCTGCTTAGCTCCCAGGTCTTTGGGTTCCTCATCTGAGAAATAGATGGGGAGGAGAATTGGGAGGAGAAACAGAGGTTAAATTGATTCACATGCAGAAAGGGAAAGGAGGCTTCCAGAAGAAAGATCTCGACATTTGGAGATAGGAGCAGGAGAGAGAACAGGAGGCGCAAGGAAAAGACCCAGGTGGACTAGAGAGGCTGGGGGAAGGCGGGAGGAAAGAGAAAGAGGTGCAGCTGGAGCCGCTGCTGGCAGGGTGGGGTGCGTGGACAGAGATGGAGAATAGACTTTTCAGAAATGTCGCTGTGTTGTGCGATGTTATCCTGCCTTTGGCATGTTTTTGAGACTTCCACGAAAACTCCTAGTATTTGTTAAGGCTTCTGGAGTTTAATTTCTGCTTTTTTTGATTGAAGCCCTATGTGTTAAAAGGCCTTAAGGCAGGAAGAAGGCCTGGCTGTATTCAGACTACATGATTTCTGTGGCTCTCAGAGAAGGACGTAATAATCAGTATTGCTTTCCTAGAATCGTCATTAGAATCTAGAGAAATGCTCTCACGTGAGAACCCTCTCACATGAAAACCCACTCACCTTCTCTCCTAAATCCCCTTAG
Seq C2 exon
AAACTGTATAAGAGCAGCTGGGAAAACCAGAAAGCAAAAGGGTTTGAGCTGCGTCTTGATTCCTTGACCTTCCTGGCAGCCAAAGCCAAGAGGGACCTGGCTAGCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197893:ENST00000359988:22
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.057 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0088013=Nebulin=PD(37.9=31.4),PF0088013=Nebulin=PU(55.2=45.7)
A:
NA
C2:
PF0088013=Nebulin=PD(37.9=30.6),PF0088013=Nebulin=PU(55.2=44.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAAGGCAGGAAATGAGCAGT
R:
CTCGCTAGCCAGGTCCCTC
Band lengths:
206-1395
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development