HsaINT0122130 @ hg38
Intron Retention
Gene
ENSG00000138735 | PDE5A
Description
phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784]
Coordinates
chr4:119502581-119504599:-
Coord C1 exon
chr4:119504536-119504599
Coord A exon
chr4:119502656-119504535
Coord C2 exon
chr4:119502581-119502655
Length
1880 bp
Sequences
Splice sites
5' ss Seq
CGGGTATGT
5' ss Score
8.79
3' ss Seq
GAGTCTGTTATTTATTTCAGATA
3' ss Score
7.73
Exon sequences
Seq C1 exon
GGCAATGCTGATGACAGCTTGTGATCTTTCTGCAATTACAAAACCCTGGCCTATTCAACAACGG
Seq A exon
GTATGTTACTTAGTGACAATAACAATAATTAAAAAGTCAAAATAACATTCTACCCAGCAATCCCACTACTAGGTATCTACCTAAAGAAAAATAAATGACTATATAAAAAAGACACTTATATGTTCATCACAGCACCATTTATTATATAATAGCAAAGTCATGGAACTAACCTAACTGTCCATCAACAGTTGATTAGATAAAGAAAATGTGGTACATATGCACCATGGAATACTATGCAGGCATAAAAAGAATCAAGTCATGTCCTTTGCAGCAACATGATTGGAGCTGGAGGCCAATTATCCTTAATGAACTAACTCAGAAACAGAAAATCAAACACTGCACATTCTCACTCATAAGTGGGAGCCAAACAGTAGGTACACACGGACATAAAGATGGAAATAATAGACACTGGGGACTCCAAAAGGGGGAAAGGTGGGAAAAGAACAAGGGGTGAAGAACAACCTACTGGGTACAATGTTCACTGTTTGGGTAATGGGTATACTAGAAGCCCAGTCCCCACCAATACACAATATACATATATACCAGACATGCACATATACCCCCTAAATCTAAAATAAAAAAAATTTTTTTAAGTAAGTTTTTACTCTTAAAGGTAGCTTCTGAAGTAAGTATGGAATTTTTTTTGGAATTTTTAAGTAGTATTAAAAACAGATAATTGGACATACAAAGGCTTTTCTTTTTAGAAGATGCATTTGCACATAATATTTGTAAGATATATTAAGAAAGAGAGCATCTACATTAGCACAGTTTTCATTTCAGTGTGAAAGGCTGAGCATACTTAATGCAAAAACCCAAAATGTTCCAAAATTCAAAGCATTTTGAGTACTGACATGACACTTAAAGAAAATGCTCATTGAACCAGCATTTTAGGTTTCAGATTTTTGGATTTGGAATATAACTTATACTTCTGGCTTACTTGTTTCTTAAGGTCATCCCTTTAATGACCTTGAAAATTAGAAGAAGCAAAATTACTTTTCTTATGGTTAGCCTTCTACGCTGTGCCTCAGCTCTAAATAGACATTAACAAGTAGAACATAGAGATTTCTGGGGCTTGTAGATGTAGGAAGTATTGATATAAGATGTCGAGAAAGTTCTGAATGGAGCCTGTTACCAGGAGGCTAGAAAAAAATCCTTCCCTCTAAGTAACTGCTATAATGTTTTGCAGAGGCAATACAGGCTCAGAAAAAGTGATGGATGTCCATGCAGTGACATATATATTGTGTTTTTGTTTTTCAAGATTTCATTTTGAGTCCGTAATAAATATGCTATTTAGGATTGTTGACAGCCTGCTGTTGGTCAAGACTCCGGGCTGCTTAGTCAGGGAGCCTAGTAACTCTTCCTACAGGCTCATCTCATGAAACAGACATGCCGAGAAAACAAGATCAAAAACTCATTCTCCATGTGCCAAAGCCAACACGCCATAAGCACTTAGGTGATCTTTACCTACCTTCCTGCCCATAATAAACAGGACTATATGCCTATTTATTTCTAACCAGGTAAGAGAATAGAAGAGGGAAGAATGTGTCTTCATATATCCTTTCTCTCCCCTGAATCAAACCCTTGTACATACTGTTTTATGGGGAGAAAATAAATGAAGAAAACATTTTTAAATAAAATTAAAAGGGAAAAATGTTGGAAGCTACCAAAGACAGAGAGATGTACCTAAGTGAAAAAGAGTATAATGTAATAGTTAAGAGAGCACGCTTTGGACATGGACTACTTGTCTTCGGGTATCAAGCTGCTGCTTATTTGCTATAAAATGGAGATATACAGCTCCTAACAGGGCCTTCATTCACGGTCTCTGTTTTAAAGAATGATATGCTTTTCATTGTCAAAACTGAGTCTGTTATTTATTTCAG
Seq C2 exon
ATAGCAGAACTTGTAGCAACTGAATTTTTTGATCAAGGAGACAGAGAGAGAAAAGAACTCAACATAGAACCCACT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138735:ENST00000354960:18
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.198
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(11.4=100)
A:
NA
C2:
PF0023314=PDEase_I=FE(10.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development