HsaINT0124818 @ hg19
Intron Retention
Gene
ENSG00000007541 | PIGQ
Description
phosphatidylinositol glycan anchor biosynthesis, class Q [Source:HGNC Symbol;Acc:14135]
Coordinates
chr16:624066-625970:+
Coord C1 exon
chr16:624066-624763
Coord A exon
chr16:624764-625838
Coord C2 exon
chr16:625839-625970
Length
1075 bp
Sequences
Splice sites
5' ss Seq
CCGGTAGGT
5' ss Score
9.39
3' ss Seq
TCCTCTCCACTCCCACGCAGAGT
3' ss Score
7.54
Exon sequences
Seq C1 exon
CCTCCCGGCATGGTGCTCAAGGCCTTCTTCCCCACGTGCTGCGTCTCGACGGACAGCGGGCTGCTGGTGGGACGGTGGGTGCCGGAGCAGAGCAGCGCCGTGGTCCTGGCGGTCCTGCACTTTCCCTTCATCCCCATCCAGGTCAAGCAGCTCCTGGCCCAGGTGCGGCAGGCCAGCCAGGTGGGCGTGGCCGTGCTGGGCACCTGGTGCCACTGCCGGCAGGAGCCCGAGGAGAGCCTGGGCCGCTTCCTGGAGAGCCTGGGTGCTGTCTTCCCCCATGAGCCCTGGCTGCGGCTGTGCCGGGAGAGAGGCGGCACGTTCTGGAGCTGCGAGGCCACCCACCGGCAAGCGCCCACTGCCCCCGGTGCCCCTGGTGAGGACCAGGTCATGCTCATCTTCTATGACCAGCGCCAGGTGTTGCTGTCACAGCTACACCTGCCCACCGTCCTGCCCGACCGCCAGGCTGGAGCCACCACTGCCAGCACGGGGGGCCTGGCTGCCGTCTTCGACACGGTAGCACGCAGTGAGGTGCTCTTCCGCAGTGACCGCTTTGATGAGGGCCCCGTGCGGCTGAGCCACTGGCAGTCGGAGGGCGTGGAGGCCAGCATCCTCGCGGAGCTGGCCAGGCGAGCCTCGGGACCCATTTGCCTGCTGTTGGCCAGCCTGCTGTCGCTGGTCTCAGCTGTCAGTGCCTGCCG
Seq A exon
GTAGGTGTCCCGGGACAGGCAGGTGGCAAAGAGTGGGGTCCCATGAGTGCTGGCCCATCCCTTTGTCTGCAGTGGGCACAGAGGCCCAGATGCGCTCTTCCTGGGCCCGGGCCCCCTCCCACTCCTGCAGCCCGGGCTTTGGCCCCATCCTGCTCTCCCAACCCTCGCCTCTCAGAGGGTGTCCCTCACCCCTGGGGTAGAGCCAGGTCTCTGGGCAGCCTCAGGGATTGCCAGGGGCCCTCCCAGAAGGTGTAGAGGGTGAACCTCAGTGGCTTAGGTCCCTGAAAGAGAAATCAGAAGGTGAGCACAGACATGACTACTGCTGCCTGGGGGTGCTCCTGAGGGCACACAGGCCCGCTGGCCTCCCTGTAGCCCTGCCTGTGCCCCCAGCAGGCCTCTGGACACTGCAGCGCTCATGGGCTGTGGGGGTGTCATCCACTTGCTGGCCCCGTGTGCCTGGGGGAGTGGTCTACAGGCCCTGCTTCTCTCCACAATCACAGGTGCTGCTGGCCAAGGGTCAGTTGAAGCCCAAGGGCCCTGAGGGGCACGGGGGTAGCCCCGAGCTGTGGCTGAGAACAGAGGGCCCCCTTCCACAGGGGACCTCATCTGCCTGGCGGAGGTGCCCCATGGGGAGCAGCTAGGGGTCACCTGCAGTTGCCCCCTGCCTTAGACCCGGGGGTGCATACTCTGGAAGCCTGGGGTGAGAAGCTAGGCCAGCCCAGGAGACCCCGGGCAGCTTTCTGGGCCCTGTCGGCGGGGCGAGGCCCTGGGCCCGTGGGAGTTGCTGCTGGCTGGCAGGCGCTTCTTGGCACCGGCTCTGGGAGCATGTGGTGACCAGGTGGCCCGGGGTCAGCACCTGCGAGGAGGCCAGGCTCCGTGTTAGTCACGTGCACTGTGAGGTGGGCGCGTTGAGCGCTGCCTACCACCACCTGGGCCACCGAGGGCCCCTCCCACCTGCCCCCTGTCCTGCTGAGCTCAGGAGTGTGGCCTGGGTGTTTGTGGTCCCCTGCACAGTGGGGGACGGTGGGAGGAGGATCTGGAGAGGGACACATCACTCCTCTCCACTCCCACGCAG
Seq C2 exon
AGTGTTCAAGCTCTGGCCCCTGTCCTTCCTCGGGAGCAAACTCTCCACGTGCGAACAGCTCCGGCACCGGCTGGAGCACCTCACGCTAATCTTCAGTACACGGAAGGCGGAGAACCCTGCCCAGCTGATGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000007541-PIGQ:NM_148920:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.035 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0502410=Gpi1=PU(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATCTTCTATGACCAGCGCCA
R:
GAGAGTTTGCTCCCGAGGAAG
Band lengths:
351-1426
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)