HsaINT0124970 @ hg19
Intron Retention
Gene
ENSG00000133056 | PIK3C2B
Description
phosphoinositide-3-kinase, class 2, beta polypeptide [Source:HGNC Symbol;Acc:8972]
Coordinates
chr1:204391758-204394869:-
Coord C1 exon
chr1:204394741-204394869
Coord A exon
chr1:204394169-204394740
Coord C2 exon
chr1:204391758-204394168
Length
572 bp
Sequences
Splice sites
5' ss Seq
ATGGTGGGT
5' ss Score
6.18
3' ss Seq
ACCCATCTCTATGTTTGCAGTTG
3' ss Score
7.8
Exon sequences
Seq C1 exon
CAACTGCTCCAGGATGGAAATGACCCTGACCCCTATGTGAAAATTTACCTCCTTCCTGACCCTCAGAAAACCACTAAGAGGAAAACCAAAGTGGCCCGGAAAACCTGCAATCCTACCTACAATGAGATG
Seq A exon
GTGGGTGGGGAAAATGGTGGGGTAGGGCAGGGGTTGGCAACCTGCGCCTGTTCTCCTAGATAAAGTCGTATTGAAGAACGTATTAAGATGTTGTATTAAGAACATGGCTGTACTTGCTGATTTAGGTGTTACCTGTAGCTGCTTTCATGTTGCAATGGCAGGATCGAGTAGTTGTAACATAGACCATATGGCTTATCAAGCCTAAAAATATTTACTATCTGTCCCTTTACATAAAAAGTTTGCCAGCCCTTTTGGGCTGGGATTTCATGGCTGGGGTCTGGCCCTATCCTGTGGGAAGGAGAAGCCTGCTGGTCCTGTGCTGAAAATGAGCAGTGGCCCCAATACAAAGCCCTCACCTGCTTGAACTCTGAGCAAAGAACAGAGTTCATTAATGCTTCCCTTGGAGTCTGTGTACCTTGTGTGCCTTCTGTATTACCTGGGACTCTGCAGGGTGAGTGCTAGCCTCAGCTGGATCAGCCCCCAACAGACTTTACCATCTCCCTCTCGGGTTCCCTCTGGATTCTTCTTGTTCCTTCTCTCACCACTTCCCTCACCCATCTCTATGTTTGCAG
Seq C2 exon
TTGGTATATGATGGGATCCCCAAGGGTGACCTGCAGCAGCGGGAGCTCCAGCTGAGCGTGCTGAGTGAGCAGGGATTCTGGGAGAACGTCCTCCTCGGTGAGGTGAACATCCGCCTGCGAGAGCTGGACCTGGCTCAGGAGAAGACCGGCTGGTTCGCCCTGGGATCTCGAAGTCATGGCACCTTGTGAGCCCAGCAGAGCCACCACCCAGCATCCCAGGCTGGTGGCAGGAGCTGGGGGAGAGGACTCTCCCCTGTGAGACTCCTCCTTGTGAAGGGCCAGGGCCCTGGGCAGGCCTCCAGCTCGGTCCAGGTGATTCTGGCCTCTGTGGTAGGAGGCAGGGAGAGTAAGACATGCTCTGCTGTCTCTTCCTCTGGAGACTGAACTTGGGTTGGTTGTGATGAGCAGCCCCTTGGAGGCTGTGAGGTTGCAGCAAAGTTTTAAGTTTACCTTGTGTCAAGGGAGCAATGCTTGGTTTGGGGAGTGTGTGGGGTGGGCTGTATGAAGTAGCATTTTGGGGGTGGGTGGGTGGATATCTTAATTTTTATTTTTAAAAAATGAAATAGTGATGTTGTCCTAACTGGGACAGGAAGCCTTGCGAGAAGGGACGTACCTATGCCCCAGAAGGCAAGAGAGGAAGACTATTTGGACTTTTTGTATGATTAAGGTTCTTATTGGACTTTTCCCTAGGTTTTTTTTTTTTGTTATTGTTGTTGTTGTTTCGTTTTCTAGCTATAGGAACTATCTGGGGAGGGGCCCAGTGGGTCCTCGGCCAGAGCCCTCTCTAAGGACAGGTTGGGGAGGGTTGGGGAGGGCTGCCTGTGCTGGACTGAGGCTTGTGCCACTGGGCCTTTCTGATTTTGCCTCCAAAGGAGAGCGCTGTGATACCTACATGTGTAAGGAAGGGCCTTCCGTATTGGGGTTCTGCCAAGGACCCGTATTCAGGGACCCATGCTCTTTTGGGGGGACTTTTCCTCTTGTCTTCCCTACTTTATTAGGACTTGCCCTGAATACCATTTTCTACCCCTTGCCCCTCCATTCTCCTGGCCCTTCTGGGGGTCAGCTGGTCTCTATGAATATGCTGGGGGTGCTTCCCCATAGGTCTCTCCCTTCATTTGTCTCTGGTGGGACAAAATACTGACTCAGTCCTTAGATGTAGTTTCACCCAAGAGCATCTTGGCCCTGGGAAGAGGTCCCTAGGCTGCAGATGCTACTGACTGCTTGCTAGGTAGCCTCTGGAAAGCATTCCCCATCCATCACTCCCCACTTCTTTCTGCTGTGCTGCTTCCCTCCCAAACTCCATTTCTGTCACCCTTTTTATAAGACTTTTCCTCATTCTGTGGGGCCATAAACCTATTTAGTCTGGAGCCAAAGGGATGCCCTATCTGAAGGAAAGGGGCATGGGGTGGGGGATTCCATCAAAACTGTTGTTTTTTGCCCCATGATTTTTCTTTGGTCAGTAGGAGGCTGGATTGGAGTGGTGATTATTCCCCTGGAGCTAAGCTCAGGAGCCCGAAGGGAGAGACTGAGACTGACTCCCTTATCTCTTCATATTCTTTATTCCCTACCAGATGGATTTTTTTTTTTTTTTTTGGAGACGGAGTCTCGCCCTGTCGCCAGGCTGGAGTGTAGTGGCATGATCTCGACTCACTGCAAAATCTGCCTCCCGGGTTCAAGCGATTCTCCTACCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGTGCCACCACGCCAAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCTTGACCTCGTGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCCCGCCCCAGATGGATTTTACATTTGCTCTTTTGTGTTTCGCTCCAAAGGGTTGTCTTCCTCGCCAAAAGGAGGGAGGGACTTTGAATTTGATATGAATCTTTAAAACCAGAATTGGCTGGATATTTCCCATGATTGGGAAAAGAGTGAAATGAGGACATTCTGTAAACTGTCCCTCCCTAATTCCAAGGATCAGAAACTCCCCGTTTTGCTGACTCATTCCATAACTGGAGAAAGAAGCTCCATTGACCGAAGCCACAGGGCAGCATGGAAGTTTAAATTTTCTCTAAAATTAAAATGCCAAGGATAAAGCTGGCTGCTTCCAGGAGGGGGAAGAGGAGTGGGGAGTGGGCGGTGAAACTTTTCCAGATGAACGGACCATAAATGTGTTACTGGCTTTGTGCCTGTAGCTCATTTTATTATGACCTATATGCTCCTGATTTAAAGAGATCTGTGTACTGTTTACTTCCCACTTCCCAGAATCCCTTGTATCTCCTTTCTCGGGAATTGTATTTTCTAATAAATGACATTTGAGAAAAAAATGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133056-PIK3C2B:NM_002646:33
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.163 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0016825=C2=FE(46.7=100)
A:
NA
C2:
PF0016825=C2=PD(38.9=55.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TACCTCCTTCCTGACCCTCAG
R:
GTCTCACAGGGGAGAGTCCTC
Band lengths:
346-918
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)