HsaINT0126155 @ hg38
Intron Retention
Gene
ENSG00000065243 | PKN2
Description
protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:9406]
Coordinates
chr1:88784639-88786213:+
Coord C1 exon
chr1:88784639-88784824
Coord A exon
chr1:88784825-88786103
Coord C2 exon
chr1:88786104-88786213
Length
1279 bp
Sequences
Splice sites
5' ss Seq
CCAGTTCAG
5' ss Score
-14.74
3' ss Seq
TTTGTAAATTTTAATTACAGATG
3' ss Score
6.83
Exon sequences
Seq C1 exon
GTACTTTGGAAGTTCGTCTTATGGGCTGCCAAGATATCCTAGAGAATGTCCCTGGACGGTCAAAAGCAACATCAGTTGCACTGCCTGGTTGGAGTCCAAGTGAAACCAGATCATCTTTCATGAGCAGAACGAGTAAAAGTAAAAGCGGAAGTAGTCGAAATCTTCTAAAAACCGATGACTTGTCCA
Seq A exon
GTTCAGTAACCAGATTTTTAAAAATCATGTAACAAACTAAAGTGCTTATACAAGGGATTTATGAAGTGTTCAAGTTGGACAAAACACTTTAAAATTATGGTTTTTATAATTTAATTAAAAAATATTAAAACCTGTGATGTCAGGAAACAAAAAGGCAACAAATTCTGTTTTGTTGAAGATACATTAGAAAACTTAATGACAAATGACATTAGTTCTTTTGGAAGAATGAAATATTGAGCATCACTCTTATGCCAAACTGAAGGTATACAGAAGCTATGAGACTGGTCCTTCTTGTAGAATCGTATCTTGATTCTTTTATTTTTCTTTATTTTTTGAGACAGTGTTTTGCTCTGTTGCCCAGGCTGGGTGCAGTGGTGCAATCAGGTCTCAACCTGCTGGGTTTAAGTGATCCTCCTACCTCAGCATCCTAAGTAGCTGGGACTATAGGCATATGCCACCATGCCTGGCTAATTTTTTTTTCTAGAGGCAGGGTCTCACTATGTTGCCCAGGATGGTCTCGAACTCAGGGGCTCTAGCTGTCCTTCCACCTCAGCCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCACCATCTCCAGCCTTGATTCTTTTAATGGTTTAGTGACACTTTAATAGTAACATTGAAATTTTGGTAATCTAACTGCTGATCCAGACGTGTTTACTGAGATAGTAGCCTGGTAGTCCACTGAGATGGGGGATGGTAGGGGTTGGTTTGAGGAGAGTAAAATGCAAGAGGTTTGGAAAGCACTGGGGAGAAATTCTGAAGTATAAGCATAAACTATATGTAGATGTATAACTGGGGGGAAAAGCATGTGACAGTTCAGCCTACCGTAGAATACAAAAGTGAATTTGCCTGTGCTTTCATGTGTATAGAGAGAGGCTTTAAGAAAAATAAGAAAATAAGGAATTGTTTAAGGAAACAAGCTCTATAAATATAAGATATAGAAAGAAAAACTGATTGATATTCACACAAACAGTGTGGCAAACAACTACTATTTATCTGTTCTTTCAGTCACATGCCAATGTAAACAAAAGAGATAGCAGTCACTATTTGTGTTTTTGTCAAACAATTTGGGAGTGTCTAGTAGGAGTATATGTATCTGTAAAACTAGCCATTTAAGATTCAAAAGTTTTAATATTGATTATGAAAAACTTTATTTTCAAAGGGTCTTAAGACTTTTATTGCTAATCAAACAGCAGTACTTCTGTTTTTTATAAAGGTTTAAAGTTTTTAAGCAAGTTTGTAAATTTTAATTACAG
Seq C2 exon
ATGATGTCTGTGCTGTTTTGAAGCTCGATAATACTGTGGTTGGCCAAACTAGCTGGAAACCCATTTCCAATCAGTCATGGGACCAGAAGTTTACACTGGAACTGGACAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000065243:ENST00000370521:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.264 A=NA C2=0.003
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTTGGAAGTTCGTCTTATGGGC
R:
CCTGTCCAGTTCCAGTGTAAACT
Band lengths:
294-1573
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development