HsaINT0132960 @ hg19
Intron Retention
Gene
ENSG00000172382 | PRSS27
Description
protease, serine 27 [Source:HGNC Symbol;Acc:15475]
Coordinates
chr16:2764066-2765881:-
Coord C1 exon
chr16:2765719-2765881
Coord A exon
chr16:2764338-2765718
Coord C2 exon
chr16:2764066-2764337
Length
1381 bp
Sequences
Splice sites
5' ss Seq
CAAGTGAGT
5' ss Score
9.1
3' ss Seq
CTCTCTGTTTCTCCCGCCAGCAC
3' ss Score
9.95
Exon sequences
Seq C1 exon
CCTGTGGTCGCCCCAGGATGCTGAACCGAATGGTGGGCGGGCAGGACACGCAGGAGGGCGAGTGGCCCTGGCAAGTCAGCATCCAGCGCAACGGAAGCCACTTCTGCGGGGGCAGCCTCATCGCGGAGCAGTGGGTCCTGACGGCTGCGCACTGCTTCCGCAA
Seq A exon
GTGAGTCCGCCCGCCCCTGCCCCCGCCCATAGCGCTGACAGCGCCCCGCGCGCGACCGGTTCAGCACCGTGGACAGCGCCCGCCGCGCCAAATCCTGCGGGTGACCTCCCTGGGGGCTCCTGGTCCAGCCCCTCCCACCCAGATGCTTCCCTTAGGTCCAACTCCAGGGCTAACTTCCAGTTGCAACCGCTGCTCCCGCCCGCGGGAGGTGCCTCGCACCGCCCCCCGACCCCCTCCATCCCCTCCACCCACTCACCCACTCCCTGTGGGTCCCTGCAGAAGCGGCCCGGCAGGCTCTGCCCACCGGCCCCTCCTGGCCTTTCCCCATCCCGCACACACCTCAGCTCCAGGACACTCTTCCCGGGAGGAACTCTGCTCACAAAGCCCAAGGACCAGACAGAACGGCCCTTCCTCCCCTCACCCACCTGAACCACCCCAGAAAGCCCTGAGCAGAGGCCAGGCCACCCAGCCCTCTGCCATGTATGAACCACCTGGTCCCACACCTTCCGGGTGTCCCAGGCCCCCTCACCTCACACCTCAACACCGCAGCTCTAATTATTTTAAACCCCACATCTTTTTCTTTTTTTTCTTCTTGATCTTTAAAAGAATATCATGACAAAAAAAACCCCACATCTTAAATTCAGATACTCACGGCCAGGCACGGTGGCTCACACCCGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCAGATCAGTTGAGCCCAGGAGTTCAAGACCAGCCCGGGCAACACAGCAAGACCCTGTCTCTACTAAAAATAAAAAAAAATTAAAAAACAAAAAACAAACAAACAAAAAAACCCCAGGTGCAGTGGTGCCTGTGGTCCCAAGTACTCAGGAAGCTGAGGCGAGAGGATGGCTTGAGCCCAGGAGTTGGAGGCTGCAGTGAGCTACAGTTGCACTGCTGCACTCCAGCCTGGGTGACAGAATGAGAACTCTGTCTCTAGGGGAAAAAAAAAATCGGAAACTCGGGCTGAGAGAGGGCAGGTCACCTGCCAGAGGCCCGCAGGTGGGGCTGGCCCTGCTGCACCTGGAGGGTGGTTCTCTCCGAGCCAGCCTTTCAGGTAGGCACTGTGACTGTCCCCACAGCACAGGTGAGAAAGCTGCATCACAGAGAACTTGTTAAGTGACTTGCCCAAGGCCACACAGCGGCCAGGGGTGGAGGTGGAAATCTGAGTCGGGCGGTCTGGCTTCAATGTCAACACGCATCACCGCTGCACCTGGCTGTCCTAGAGATGACTCTCGAAGACATTGTGCAGAGAGAGGTGTGGGGCACGGTGGTGGCCAGAGGAGCCCCAGCCCCTCCCGGGCCTGTCCCCACACGAGGGGCCGCCTCACGCCGCCTCTCTGTTTCTCCCGCCAG
Seq C2 exon
CACCTCTGAGACGTCCCTGTACCAGGTCCTGCTGGGGGCAAGGCAGCTAGTGCAGCCGGGACCACACGCTATGTATGCCCGGGTGAGGCAGGTGGAGAGCAACCCCCTGTACCAGGGCACGGCCTCCAGCGCTGACGTGGCCCTGGTGGAGCTGGAGGCACCAGTGCCCTTCACCAATTACATCCTCCCCGTGTGCCTGCCTGACCCCTCGGTGATCTTTGAGACGGGCATGAACTGCTGGGTCACTGGCTGGGGCAGCCCCAGTGAGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000172382-PRSS27:NM_031948:3
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.118 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(18.5=80.0)
A:
NA
C2:
PF0008921=Trypsin=FE(38.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGGATGCTGAACCGAATGG
R:
GCACACGGGGAGGATGTAATT
Band lengths:
347-1728
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)