HsaINT0136510 @ hg38
Intron Retention
Gene
ENSG00000161800 | RACGAP1
Description
Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804]
Coordinates
chr12:50005256-50006636:-
Coord C1 exon
chr12:50006434-50006636
Coord A exon
chr12:50005393-50006433
Coord C2 exon
chr12:50005256-50005392
Length
1041 bp
Sequences
Splice sites
5' ss Seq
CTGGTGTGT
5' ss Score
4.96
3' ss Seq
TACTTTGCTTTGGTCTGTAGGAA
3' ss Score
8.05
Exon sequences
Seq C1 exon
AATTTATCCAGTTGGCGAAGGACTTTGAGGATTTCCGTAAAAAGTGGCAGAGGACTGACCATGAGCTGGGGAAATACAAGGATCTTTTGATGAAAGCAGAGACTGAGCGAAGTGCTCTGGATGTTAAGCTGAAGCATGCACGTAATCAGGTGGATGTAGAGATCAAACGGAGACAGAGAGCTGAGGCTGACTGCGAAAAGCTG
Seq A exon
GTGTGTATTGTTTTCCGTGCTAGAACAGTGATGATGCAGGAGGGGGAAGGCATTGTCTGACAGTTTCCACTTGCCAAATATACCTAGTTTCTTCTTCCACATTAAAGAACTGAAAGTGACCTGTTCTTTAACAGCTTGCCCATGATTAGAGCTGAAATTGCAGACTAGGAATCTTGTTCTTCATAATTTGAAATTTAAATGTTTTTGTCACTTAGACTTGAAACTTACTTAACAGACAGATTTCAAATGAGAACTTAAAGAATTAGAGGAAAAGGGAGGGAGGGAGATCCTAACGTACTTGATCTGTCACAAGTTATTGGCCATCCTTCATTGTTTATTTTAAGTGCTACCCGGAATATCCATCCTTACATGAGTAGCTGGTACTTTGTCATACATACAGGCAAGACAACTGTGACTCTTCTTTTCATCACCCCTCTCTAATTCAGGGTAAAAGGCTAGATGTATTCAACCAGTTGAGCAATGTGACTGACACAGAACACTATCATTTTGATGTGCCAGGATGGGTCATAATGCAAAGGAAAGCCTTTACTGGGAGGGACTAATCCATCTTGGTATACAGTGTTAGATGCCTCAGTAAACTCAAATTGTCTGGTTCCAGTGCATTATAGCTTTGTATCCATTTTAATGCATTTTGCTCCACTACTTTGAGAGGTGGGTGGCTGCTTTGATCCGTAGAAGCCAATATTTGTCCTGATAAAATGACACTAAAGTGTTTTTGCTATGTGAAATCTATTTTGGGACTCTCATTTTGCATTATTCTCCTCTTGGATTAGCAGGTTAATCCAAAAGTCTTGTAGCAGAAACTTCGCTGTTCTAGATGTAGTTCATTTTACCAGTCAGAAATCAGAGACACAATCTGGGTTTGATGTGAATTAATATGCTATTGGTGTAGCAGCCTTCCTGAAGGTCCATTTGCATAATGCTGCATTTTAATGTCTTCTGGTCTGCCTGTCCCATAAACTTGAGGTGAAGCTTTCTCCCCTGGCTAGTTATGATGTTTTACTTTGCTTTGGTCTGTAG
Seq C2 exon
GAACGACAGATTCAGCTGATTCGAGAGATGCTCATGTGTGACACATCTGGCAGCATTCAACTAAGCGAGGAGCAAAAATCAGCTCTGGCTTTTCTCAACAGAGGCCAACCATCCAGCAGCAATGCTGGGAACAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000161800:ENST00000312377:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.026 A=NA C2=0.305
Domain overlap (PFAM):
C1:
PF111803=DUF2968=FE(60.4=100),PF078886=CALCOCO1=FE(53.6=100),PF140731=Cep57_CLD=FE(54.0=100)
A:
NA
C2:
PF111803=DUF2968=PD(14.4=34.8),PF078886=CALCOCO1=FE(32.1=100),PF140731=Cep57_CLD=FE(32.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
ENSP00000404190, ENSP00000404808, ENSP00000447177, ENSP00000447393, ENSP00000448136, ENSP00000448697, ENSP00000448707, ENSP00000448860, ENSP00000448968, ENSP00000449170, ENSP00000449186, ENSP00000449370, ENSP00000449374, ENSP00000449620, ENSP00000449669, ENSP00000449959, ENSP00000449963, ENSP00000450064
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCAGTTGGCGAAGGACTTTG
R:
CTTTTGTTCCCAGCATTGCT
Band lengths:
334-1375
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development