HsaINT0137685 @ hg19
Intron Retention
Gene
ENSG00000111344 | RASAL1
Description
RAS protein activator like 1 (GAP1 like) [Source:HGNC Symbol;Acc:9873]
Coordinates
chr12:113549891-113552717:-
Coord C1 exon
chr12:113552605-113552717
Coord A exon
chr12:113550084-113552604
Coord C2 exon
chr12:113549891-113550083
Length
2521 bp
Sequences
Splice sites
5' ss Seq
CCGGTGAGC
5' ss Score
8.69
3' ss Seq
TGCTCCGCCGGCCCCTCCAGGAG
3' ss Score
7.21
Exon sequences
Seq C1 exon
CTCGTGGGCATGCCCTACCTGCACGAGGTCCTGAAGCCTGTGATTAGCCGTGTCTTTGAGGAGAAGAAGTACATGGAGCTGGATCCCTGCAAGATGGACCTGGGCCGCACCCG
Seq A exon
GTGAGCAAAGCCTGAGGACCCTGACCTTCCGACGGGCCCCTTTGGCTACCCGGAGCCTTGTCTGGGGGCTGGGTTCATGCTGACTGCCACCCACCCTGGGGCTACAGCTGCTCAGGAGCTCGGTGGCTGAGCTGAAAGCCTCACACACAAGCCCTTAAACCATCAGGCTGTGTAGTATAGGGGTTATGGTCAGGACTCTGATGCTAAGCGCCCTGGGTTCAAATCTTAGCTTTGCCACTACTGGTGGACAAAGTTGCCAAAACTTCTGTTCCTCAGTGGTTAAGTTGCTTCTTTTCTTTTCCTTTTTTTCTTTTTTTTTTTTTTTTGAGACAAGGTTTTACTCTGTCACCCAGGCTGGGGTGCAGTGGTGTGACCACAGCTCACTGCAGCGTCAACTTCCCGGGCTCAGGTAATTTTTCCACCTCAGCCTCCTGAGTAGCTGGGACTATAGGCGCACACCACCATGCCCAGCTAAGTTTTTACATTTTTAGCAGAGACAGGGTTTTGCCACATTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGCAATCCTCCTGCCTTGGTCTCCCGAAGTGCTGGGATTACAGGCGTGAACAACCGTGCCTGGCATAATCAGATTTTTTAAAATTAAAAAACCTAAAATATTGATCCAATGTTCTTCTACTTAATGCACACACTACTTCTAAAATGTCCCTTATCCAGCTGGTGAGAATATTATCACCTGAAACGTGGGGCTCATGACCTCTGCTCCGTTAACTGAGTCATGCATGTGCTCCACAAGCATTAGTGATCTTTATTACTGTGCTGCTGGGGCTCCTCGACATTAGTGATATTTACTGCTGTGCTGCTGGGGGTCCCCAACATTAGCGATTTTTATTATTGTGGTGTTGGCGGTCTCTGAGTGGGCCTGCCTGCAAGGGAGATCGTGGAGAGCTCAATGAGATTGGGAGGAAGCAGAGCAGTGGCTGGGGGTCATTCCACCCCTCCGTGGGCTCCTCCTTTCTCTCCAGAACCTTCTCCTGTCTAACCCACAAGCCTGGAGCTGTGGAAAATTGTTGCTGGGGTATCCACTGGGGACCGTGGCAGAGACAGGAGAGGATCTTTCCTTGTGCTGTCCACACCTTCTGACTACTTTAGAGGCAGGCATCATGACCCCCTCTTACTGATGATGCAACTGAGCCTCAGAGAGGGAAGGTCACTTGCCTAAGGTCATACAGCCAGGAAATTACAGAGCAAGGATTTGATCCCAGGCCCTGAGCAGAAGGACACAGTCCATCTGTGAGACTCCAAGTTGAGGGCTTTTCCTAGCACACTTGATAACGATGGAGGAAACTCAGTGGGCACCCATGGGGACAGGGGCATGTAGGGACCTGGACAGGGCAGGGTTGCAGGCAGGCTGTGGAGTTGGCAGTCCTGGGTTCTATTCTCAGCTGTGCCATCTCCCCAGTAACCTCTCTGAGCCTCAGTTTTCTTATCTGTTAAACGGGAACAAGTAAGGCTACTTACCCCATCAAGTTGCTGTTAGGATTAAAAGAGACCATGCCAGAGACAAGTCCAGGGCTCAGCACGTTGGGTCCAGGACACAGTGGGGCTGAGAACCCCCAGCTGTCACTCTAGGTGTGGGCAAGACAGACCCTCAATCTGTAAAGAAAGAAAGGAACACAATAATTGCAGATGGAAAAGTGCTGTTCTAGCATCCACAAAACAAAACAATGATTGAGTGCCAGGCTCTGGGCTGAACACTGACGATACAGTAGGGAACAAATAGTCCCAAGTCCCTATTCTGGGGGGAGACAGATAATGAGCAACTGGAGGAAGAAGGTTTATTTATTTATTTATTTATTTTTTGAGATGGAGTCTCGCTGTGTCACCCAGGCTGCAGTGCAGTGGTGCGATCTCGACTCACTGCAACCTCCACTTCCCATATTGAAGCGATTCTCCTGCCTCAGCATCCCAAGTAGCTGAGATTATAGGCGTGCACCACCACGCTGGGCTAATTTTTGTATTTTTTGGTGGAGATGGAGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGGTCTCAAGTGACCTGCCCCCTCGGCCTCCCAGAGTGCTGGGATTACAGGCATGAGCCACCGGGCCTGGTTGGGAAAAGGTTATTGAATGGGACCAGGGAATGGAATAAACGAGGGAGGGGAGAGGCCTGCAATATTCCAGAGGGTGAGGACAGGGGCAGCCTCGCAGGGGAGGGGACATCTAAGCAAAGACTTGCAGGGGGTGAGGAAGGGAGTGTTGCGGAGATTTAACATTTAACGGGAGAGTGTTCTGGGCACGGAGATAAGCCAGTGCAAAGGCTGCAGGATGGGAATGAGCTCATCGTGTTTAAGCAACAGCAAGAAACCCGGTGGGAAGGGGCAGGAAGGAGGCTGCGGACGTGGAGGGAAGATGAGTCCTCTCGGAGCTCAGCGGGGCCGGTGGAGGGTTTGGAGCAGGCAGATGTTGTGCCCCGAGGCTGAGCTGCTCCGCCGGCCCCTCCAG
Seq C2 exon
GAGGATCTCCTTCAAAGGCGCACTCTCGGAGGAGCAGATGCGGGAGACCAGCCTGGGGCTGCTGACGGGCTACCTGGGGCCCATCGTGGACGCCATCGTGGGCTCCGTGGGGCGCTGCCCGCCCGCCATGCGCCTCGCCTTCAAGCAGCTGCACCGGCGAGTGGAGGAGCGCTTCCCCCAGGCCGAGCACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000111344-RASAL1:NM_004658:13
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0061614=RasGAP=FE(19.5=100)
A:
NA
C2:
PF0061614=RasGAP=FE(33.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)