HsaINT0137701 @ hg19
Intron Retention
Gene
ENSG00000075391 | RASAL2
Description
RAS protein activator like 2 [Source:HGNC Symbol;Acc:9874]
Coordinates
chr1:178426818-178433547:+
Coord C1 exon
chr1:178426818-178427679
Coord A exon
chr1:178427680-178433412
Coord C2 exon
chr1:178433413-178433547
Length
5733 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGGT
5' ss Score
10.28
3' ss Seq
AATAACTGTTTCTGATGCAGGTT
3' ss Score
9.09
Exon sequences
Seq C1 exon
TGATTTGCATAAACTAAAATCTCCAAGCCAGGACAACACAGACAGCTACTTCAGAGGGAAAACATTATTGCTGGTTCAGCAAGCCTCCTCTCAGAGCATGACTTATTCTGAAAAGGATGAAAGGGAAAGTAGCCTTCCTAATGGTCGGAGCGTCTCCCTCATGGACCTCCAGGACACTCATGCTGCTCAAGTGGAGCATGCATCTGTCATGCTTGATGTGCCTATACGCTTGACCGGAAGCCAGCTTTCCATAACCCAGGTGGCCAGCATCAAACAGCTGCGGGAAACCCAGAGCACTCCCCAAAGTGCACCCCAAGTGAGAAGGCCCCTGCACCCAGCCTTGAACCAGCCAGGTGGCCTTCAGCCCTTGTCGTTCCAGAACCCTGTCTATCACCTCAATAACCCAATTCCAGCAATGCCAAAGGCCTCTATAGATTCCAGTTTGGAGAACCTAAGCACTGCCAGTTCCAGAAGCCAAAGTAACAGTGAAGACTTCAAGCTCAGTGGACCCAGCAATAGCAGCATGGAAGATTTCACTAAACGTAGCACTCAGAGTGAGGACTTCTCCAGGCGGCACACGGTGCCAGATAGACACATACCTCTTGCTTTGCCACGACAAAATAGTACTGGGCAGGCCCAGATCCGAAAAGTGGACCAGGGTGGGTTAGGTGCCCGAGCCAAAGCCCCACCATCCCTGCCACACAGTGCTTCTTTACGTAGCACCGGGAGCATGTCAGTGGTGTCCGCAGCCCTGGTGGCCGAACCTGTGCAGAATGGGAGCCGGTCCCGGCAGCAGTCCTCTTCCTCCAGAGAGAGCCCTGTTCCCAAAGTTAGAGCAATCCAGAGACAACAGACACAGCAG
Seq A exon
GTAGGTGTGAGTGCTGAAGGGGCCTGGCTTCTACTTGGTCCATCTGTTTCCTTGGTTCTTTATACATAAATCATTGGGAAATCCTATTGTTAACAAGATTTCCTCTTAAAAGCAACCTTTAAATGGAAAGAGGAAAGGAAAAATTTGGGAGGCTTCTGCCCAGGTGTGACTACAGAATGTAGTTTGACTCATTACCCTTAAGAGTCTAACAAACACGCAGAGGCCCCCTTCCTTCTCTTCAAGCAGCAGAGCTGCTACCTCAGTTTGCACTTAGAGCAAATCTATGATGTTGAATGAATAATTAGATACTTAAAATCTGTAGGCAAAACCAGCTATTATTTTGGAAATCTGAAAATTAATCCTTCTTAATTTTTTTTCTTAAGCTTCCAGAATAAAGGTTTGCATTCCGAGCCAAGAGTTTAATATGACTGCTCTCCATTCCATCCCTCAACTCCTTCTGGAAATACAAAGTCCCATGTGGCTTTTCCTGGAAATAGCTAGAAAAATAAACACTTGAACACCTGTAGAGTCAAGGTAAAGGAGAGAGTAAAAAGATAGAAGCACAGGTGGAAAAGGAAGTATTCTAAACATCTGCAAATCCCTTACATTTCTATTTACATGGACAAGCCCAGCTAACATCACATCCAATCTTAATATAAGTTTTTCTAATTTTTTTATTGACAAATAAAAAGCTTTGCCAAGAAACTAATCATTTCTTCCTTAAATATTACATTTTGAAGCATCAATACATATTTTTCCCTTTGAAACAAACTACTGTTAAATATATAATATACACATTCATATAATTTTTCATGTATATAATATATATCTTTATATATCTTTCATCTAAAAAGATTTTTCTCCTAAAAAAGCATTGTATTAGTTGAATTTTTTTTGAAACCTAATGATAGTACTAAAAAACTTGAGATTAAAAGAGTTCTATGACAAATCCTTTTATGCAGCAAAATAACTGGGCAGGGAGACTGCAATAAAATCCTAGTTTGTATCTGTTATATATTTGCATTTTTACAGTTTAGGCACTTACCTATATGGCTGCCTCTGCCTCCAGTCTGCTATGATCAGAGCCCCTTGCACCTACTTTGATTTTTTAATTGGATTATTTATAGAATCCTTGGATACAGAAATAGAAGAAGGGATGAAAAGCATGACTAACTTAAGCTGTTTCTGGAAGCAGACTTCCTGGGCTAAACCTCCTAGTTGGTCATTTTTTACTGAGTAATAAAGTTTTTCTACAGTCTTAAATTTTTCATTTTTATTTTGTTATATTTCCCAAAATTTTACCAAATCATTTGATTTAGTAAGCATTTTTATTTGAAGAAAAGGAAAAATAGATATCTTTTATATGTATCATATGTATTTTTTATATATAAATGTGTATGTGTATATAAGCATAAAATGTATGTGTTAGAAGGCTATCAGTCATTCCTACCTTATTGTGAAGTAGTTTCCTCACATCACTTTTGTGCTAGATTCTAGTTGCGATCAACTACTTTCAGAGAATTAAGATGTTTATTGGGAGGAGAAAGGAAAAAATACATAATTTTAGAAATCAGAATACTGTGTAGAAGCAAATATCTACTCAGGGACTTAGGGCAGCACAAGGGCACTGAAGATAAAATAGGATTAGCGAAGAGCATGAGATCTGGCAGAGAGGGACAGGACAGGGAAAGTGTCCTCCACCTGCTTTTCAAAAGTGTACTTAGGCCCAGCCCTGTACAGAAAAGGAAAATAAAGATTCTTTTTTTTTTCTTTTGCTTACCCTTTCCTTCTGTATCATGGAGGGCCTATGACTCAGGCTGGTTGTTTATTAATATTATAAATTAAATAGCCTTTTTTGTGCTCATCTGGAACCAGTTGTCATTTATAACATTTTTTCTTTAGGAAAATACAATACCTATCGCATAAGCACATAATACATGTTTCTGTGGGTTATGATTAGAGGGCTGCCTGGATGGATGGGAGGTAGGAAATGCATACAGTCTCCAAACAACCAATATAAAAATTAGTTTTTGTGTCACAGCCATTAATGAGTCACCAAATATATTTTTTGGCATGAAGTGGGGTACAGGCACAGTGAGATGTCCAGGTACAGCTTTGAATATTAATCTTTGTTTATACTTTTGCTGGTACTGCCACTGTCCTATCAGTTGAAGCATAAATCACCGTATTTTGATTGCTCAAGTTTCTTTTTTTTTTCCTACACTGGCTTTTGGTTCATTGTTTTGAACTTACATTGTTAGTTTTTTATTTTTATTTTTATTTTTTTGAAACAGAGTCTTGCTCTGTCGCCTAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGTAACTTCCGCCTCCCAGGTTCAAGCAGTTCTCCTGTCTCAGCCTCCTGAGTAGCTGGGATTACAGATGCCCACCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGGTGGGGTTTCATCATGTTGGCCAGGTTGGTCTTGAACTCCTGACCTCAAGTGATCCACCTGCCTCGGCCTCCCAAAGTGCTTTGATTACAGGAGTGAGCCACCGTGCCTGGCCTAGTTTTTTATTTCTTATCTGTTTCTTGCTTGCTTTGTTCATCTCACTCCCATGAAGCCTCTGAAGTTCTATATAATCAGCACATTTTTAAGGCAAATTCCTTTACATATTTTAATTGCAAATTGTGTTGGGGAATTCTCTCCCAGAAACTAGAGGATTTCTTTGTGGGGATTGTTCTGTAGGCGGCTGTAATTATCAGTAGCTTTGTCCCATGCAAATTCCATTTATATCTTAGCACAAAGTAGTGGCCATTGTCTGCAGAGTAACTGGCTTCAGTCTTCTACGTCTAATGAGTAGGAAGGAAATAAAATCCTGGTGAAAAAATTCACAGATAAATTTTTTTTCAAGAAACTCTCTTAATTTTTTAACCCATTTCAGCCTCTGTTTGTATTGCTTTTTTCTTATTTTCCTCTCTATTTTGTTTTTCATGTATCATCTACTTCGTACAAACAGTAGACTTTATATATATGAGTTGTTCAGATTTATCATGTACTCTAATCTTAGAAATTTGAATTTGAAGAGACCTTTTAAAATAGATAATTGACAAGCCTGTTAATATGATGCTGCAGTTTTCACATTTAGATTTGTTGAACTGTCTCTTAACCAACCTCTTCAAGAACTCCCAAAGTTTGTGGATTAATTTATTCGGCCCTTTCTTTGGTGTTGATAGCAGAAGGGTTATTCATTTATGGGAATCCGACTATTTCACACTATGAAGCTGAAACCAATTGGTCTTGTTTATGTCTAGTAAATACTAGCAAGGAACGAGGAACTGGCCTCAGCATAGCCAGGCTATGATTAATTGTAGTATCAGTGAAACTGCTGCATCAGGCTCTTTTGCCCTAAAGCGTTACTGTTTTTCCAGGGAAACCCTATACAGCTTTATCTCAAAGGGAAGATATTCCTAATGGGAATTCCTGCTCCTTTTTCTTTTTGTCTTTTTCATTATCTTTGATGATCATGTTGAAAGTCAGTGGATATAAATTCTCTTTCTAAGGCCATTCCTAAGCAAGATGGAATCTGAACCACTTACTAACCTCCTCCCTCAATTTTTTGGACTATAAACTAGAGATATTTTTTGCTATTTATCCAGCTTATAAGGAGATGGAACAATCATTGAAAAGAAGCCTTTGGTGCCCTTCCAAAGGATTAGGGGAAAAACATAGAATATTCTCTAAGTAATAAATTATATTTTAGTAATGAATTCTAAAGATAATCCAGAATAATAAATGAATAATATTTTATTGAGCATCTGTTGTGTATTTAACTAGTCAGTATCATTTAAAAGAACTGTATGATATGATGCCCATTAGATTGACTAATTGGAAAATAAGAGCAACGCTTATAAGACCAAGAATATATAAAAGATAGTATATAGTTTTTTCATTTGAAGAACATACTACAACAAAAAAATTCATGAAACAAAAATCACCTCTGTTTCCTTTCAATCTAGCACAATAACTATTTTTTATTTATTCTATATTTCTAGCCTTTTTACAATTTTGTGAAGGCTTTATCATTAATAGAAGGAATAGTTAGGATTGATCTATTTTGTCACTTTTATTTTTATTATTTTGACCACCTACTGTATGCCAAGCAAAGTGCTAGGATATATTAGGAAGTGGCTGAAAATAAGATTTGACCAACAAAATAGTAGAAATTTCTAGAAGTTCATTCACAATTGCTTAGTGTGTACGGGTCTATTTATATAAACTATGCACATCCATCCTCAGGCATGAAGCTATTTTTATTGATATATAACTATAATCTGTAAATCGACTAAACCAGATCTTTCTTCACACCTTTAAGAAATGTCCCTATGTTACTTTTGCATGTGTAAGTTTTAAAGTCTCTCCCAACCCATCTCTGATAGCCTTTTAGTCTCTGCAATCAGTTTTTTAATCTGGTCTTCCTCACTCTCCAGTTCATCAAAATACCCCTTCTTTTAAAATATTTATTTAGAGTTTAACTGAGTTCTATTTCAGAATGGTATAAAGATCCTTAAGATGTAATGGCTGTGATAGGGGAGAAAATGCCCTTCAATTATGAAATTATGGAATTCTGGTCCTTAAAATACAAATCCCTCTATTTAATTATAAAAGGCTAACTCACATGCCAAGTTTTGTACTCTCTCTTTAGCTTACTCTCTCTCTCTGAGGCAGGACAGAGGGGAAAAAAATTGTGTGTTTCCATCATTGTTTGTGGAGAAAGCACTAATGTTCAATAGCCTAATATAAATTGTAATATCTAATGCTAGTTTTTGAAACATAAATATTGTAATGACTGACACCTAACCTCTCTGTAGCACTCTGAAGTTTCCAAAGAATTTTCAAATATATTGTCTTATCCTCACAGCTCCCTATGAGATGATCAAGATAGGTGGTGGTGACAGTGTTGGTATGTCTATTCAGTAGATTAGGAAAATAGACTACCCAGTATCCATCATTTTGATCCTGTATTCAAGAAATTTTCCAGTATAAGGACCCTTGAGTGATCTTAATCCATCATGAAGTCAGTGTTCTGTAAAGATAACCAGCATCACTTGTCCTTCTTTTTCTCTAAATCAATAATATGAAAACTAAATAGACTGGTGCAAAAGTAATTGCAGGTTTTGCCATTTAACCCACAATTACTTTTGCACCAACCTAGTATTTGCCATTCTGATATATAAATGGGCACTTTGTGAGTTTGTTTAGCACTAATCAGTTTTTTGGTTTCTGATTGTGTCTGGGCTAAACAGATATTTTGACCATCAGGTTATGCTTTCTTTCTCTTATTTAATCATCAAATAGACTTTTATGGCATAAAAGACTTTTATGGCAGAGGTCATTTATTAATTTCAGCAGGCAATTTGTTACCTACCAGTATTTGGACCACTGGGCAAATTAACAATTTTAAGGCTTTGACTTTCTTTAGAGGGAGAATAAGGATGCCTCTTGGATATGATATATGCAACTTTCTATTCAGAATAGTTTGCACTTATACAAATGTATATTCTCTTTCCCCACCCCTAGCCTTGGCATTAGTAAAATAATACTTAAAGCTAAGAGCATTTATTAGAAAACTGAGAGATCACAGTTAATGTCTTCCAAGAATAGCTGTTTGTGAAACATAGCACACGGGTGAGCTGTTAGGGGAAATGCTAATAACTGTTTCTGATGCAG
Seq C2 exon
GTTCAGTCACCTGTGGACTCTGCCACAATGTCCCCAGTAGAGAGGACAGCAGCCTGGGTTCTGAACAATGGGCAGTATGAAGAGGATGTGGAAGAAACTGAGCAAAATCTAGATGAAGCCAAGCATGCTGAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000075391-RASAL2:NM_004841:12
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.885 A=NA C2=0.978
Domain overlap (PFAM):
C1:
PF120043=DUF3498=FE(57.2=100)
A:
NA
C2:
PF120043=DUF3498=FE(8.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)