HsaINT0137729 @ hg38
Intron Retention
Gene
ENSG00000105122 | RASAL3
Description
RAS protein activator like 3 [Source:HGNC Symbol;Acc:HGNC:26129]
Coordinates
chr19:15458529-15460258:-
Coord C1 exon
chr19:15460203-15460258
Coord A exon
chr19:15458656-15460202
Coord C2 exon
chr19:15458529-15458655
Length
1547 bp
Sequences
Splice sites
5' ss Seq
TGGGTAAGG
5' ss Score
9.08
3' ss Seq
CTCACCCACCCCCTTCCCAGACC
3' ss Score
8.69
Exon sequences
Seq C1 exon
GGGTTGCTCAAGAGGCTGAAAGAGAAGAAAAAGGCCAGGTTGGAGCCCCGGGATGG
Seq A exon
GTAAGGGTGTATGAGAGGCTGGAGGGGCTGGGGTTCAACACTGGCCCCTCCTCCTCCACCTCCTGCATATCATTCCAATCTACACCAAACACCCCCTGTGGCCTCTGTGTTCTGCCCCACATCAGTTGATGCTGGGGACATTGAATGATCTAGCACAGAGCCAGGGTGGGGGCAAAGTCTGACACAATAACTCTAAAATGGGAGCTAAGTCAATCAACTGGTCTGGGAGGGTTAGGGAAGGTACCCTTGAGCTGAGATCTGAAGGGTGGATGGAAGTTAACTAGGCCAACAGGGGGGTGGAAAAAGCATTCCAGGCAGAAGGAACAACAAGTGCAAAGGCCAAGAGGCCGAAAGAAGCAACTAAAACAAGGCCAAGAGGGCTGGGTGAAGTGGCTCCCAGCACTTTGGGAGGCCAAAGTGGGCAGACTGCTTGAGTCTAGGAGTTCGAGACCAGCCTGGGCAACATAGTGAGACCCCATTTCTACAAAAAATACAAAAATTAGCTAGGCATGGTGGCGGGCACCTGTAGTCCCACCTACTGGGGAGGCTGAGTGGGAGGATTGCTTGAGCCTGGGAAGTTGAGGCTGCAGTGCACAGAGATCATGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGATTGTGTCTCAAAAATAAATAGGGCTGGGTGCGGTGGCTCACACCTGTAATCCCACAGTTTGGGAGGCAGAGGCAGGTGGAACATTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACGTGGTGAAATCCCATCTCTACTTAAAATACAAAATTAGCCAGGCATGGTGGCGAATGCCTGTAATCCCAGTTACTCAGGAGGCTGAGGCAGAAGAATCGCTTAAACCTGGGAGGTGGACATTGCAGTGAGCCAAGATTGTGCCACTGCACTCCTGCCTGGGCAAAAGGGCAAGACTCCATCTCAATAAATAAATAAATAAATAAATAGGGCTGGGCACGGTGGCTCACACCTGTAATCCCACACTTTGGTGAGGCTGAGGCGGGTGGATCACTTGGGATCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCACCTCTACTAAAAATATAAAAATTAGAAAATTAGCCAGGCATGGTGGTGGGCACCTGTGATCCCAGCTACTTGGGAGGCTGAGGAAGGAAAATCACTTGAACCTGGAAGGCAGAGGTTGCAGTGAGCTGAGATCCAGCCACCGCACTAAACAAGACTCTGTCTCAAATAAATAAATAAATAAATAAATAGGATAAAATAAAACAAGGCCAGGGAGGCTGGAGCTCAGAAAGTGATGGATTAGGTGGAGGGAGATGAGGTGACAACATCTGGACCCAGCTTGGTCATGTAGGTCACCAGGAGTTGAGTTTATCCTAAAAGCAAGGAGGTGCCATGGCGGGGGGTGGGGGGGGCACGGGGGAGAAACGGGATCCGAATTGGGTTGAAGTCCTTCCTGGCCTTCCTCTACCCTTCAGGCTATGGGGGATGGGGAAGAGGCAGGAATGACGGTGTGCTCACCCACCCCCTTCCCAG
Seq C2 exon
ACCCCCCAGTGCTCTGGGCTCTAGGGAGTCGCTGGCCACACTCTCTGAACTGGACCTGGGTGCCGAGCGGGATGTGCGGATCTGGCCACTGCACCCCAGCCTCCTGGGGGAGCCCCACTGCTTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105122:ENST00000343625:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.842 A=NA C2=0.314
Domain overlap (PFAM):
C1:
PF0016924=PH=PU(16.1=73.7)
A:
NA
C2:
PF0016924=PH=FE(48.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGTTGCTCAAGAGGCTGAAA
R:
CTGAAAGCAGTGGGGCTCC
Band lengths:
183-1730
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development