HsaINT0145208 @ hg38
Intron Retention
Gene
ENSG00000188322 | SBK1
Description
SH3 domain binding kinase 1 [Source:HGNC Symbol;Acc:HGNC:17699]
Coordinates
chr16:28318995-28323849:+
Coord C1 exon
chr16:28318995-28319197
Coord A exon
chr16:28319198-28320075
Coord C2 exon
chr16:28320076-28323849
Length
878 bp
Sequences
Splice sites
5' ss Seq
CAGGTACTC
5' ss Score
7.04
3' ss Seq
CTTCCCCCGGCCGCCCGCAGGTG
3' ss Score
10.51
Exon sequences
Seq C1 exon
GCACAAAAATGGCACTGAAGTTTGTGAACAAGAGCAAAACCAAGCTGAAGAACTTCCTACGGGAGGTGAGCATCACCAACAGCCTCTCCTCCAGCCCCTTCATCATCAAGGTCTTTGACGTGGTCTTTGAGACAGAGGACTGCTACGTCTTTGCCCAGGAGTACGCACCTGCTGGGGACCTGTTTGACATCATCCCTCCCCAG
Seq A exon
GTACTCGGGATGGTGGCATAGGGTGGGGAAAGGGTCTTCAGGGTCCCAGAGTGTGAGAGTGGGAGTGGAGTCAGACCATTTAATTAACAAGTATTTACTGGGTGCCTGCTGTATGTCAGTTACCATTTGGGGAGGTGGGGATGTGCAGTAAGGAAGACAAAAGTCCCTGTTCTAGTGGGAAACTGACACTCCACAGCGGGCCAGATAATAACAGATGGAGATGAGTGCCTAAAAGGAGACAGTGAGAATGATGGGATGAAGTCACTGGGCCCTCCCCTGGGGCTACACAAGAGGAGAGGTGTCAGATCCACCTGGGAAGGGGCCCTCAGAGGAAGCGACCCTGGAACCGGGACGGTGGGGGAGGGTTCCAGGCACTAGCTTTAAATCTGCTCTGCCACTTGCTGGCTGAGTGATGAGACCTTCGGAGCAGGTCCTCCTTCTTTGCTGAGCACCTACTACATGCCAGAATCTGGAGACACAGATGCACGGACACAGCAGGGAACAGGACGGGAAGCTCAGGGAGCCCCGTTCTAGTTGGGGAAGACCGACGAGATAAGTATCTAGCAGGCAGGGCAAAATGACAGCAGGTGGAGGGCGCCGCGGACCCCCTCATCAACCTCCTGGAGAGCCGCGTGTCCCTCCTGGAGCCCCGATGTCCCCATAGGAGAAGCAGGCATGGTAGCCACTATGAGGATTGGATGAGACAGCGGGGGAAAGGGCGCTCAGCAGCATCCGGGCCGCGTCTGCGCGGTCGCCCCAGTTACTGGGGACAGGGTGGGAGGCGAAAACCGCCTTGCTAGAGAGGGAGCTGGAGGGGAGGGCGGCGGGGCGGGCGCTGGAGAGCTGGAAACAGCGCGGCTTCCCCCGGCCGCCCGCAG
Seq C2 exon
GTGGGGCTCCCTGAGGACACGGTGAAGCGCTGTGTGCAGCAGCTGGGCCTGGCGCTGGACTTCATGCACGGGCGGCAGCTGGTGCACCGCGACATCAAGCCCGAGAACGTGCTGCTGTTCGACCGCGAGTGCCGCCGCGTAAAGCTGGCCGACTTCGGCATGACGCGCCGCGTGGGCTGCCGCGTCAAGCGCGTGAGCGGCACCATCCCTTACACGGCGCCTGAGGTGTGCCAGGCGGGCCGCGCCGACGGGCTGGCGGTGGACACGGGCGTGGACGTGTGGGCCTTCGGCGTGCTCATCTTCTGCGTGCTCACCGGCAACTTCCCGTGGGAGGCGGCGTCGGGCGCCGACGCCTTCTTCGAGGAGTTCGTGCGCTGGCAGCGGGGCCGCCTGCCGGGGCTGCCTTCGCAGTGGCGCCGCTTCACCGAGCCCGCGCTGCGCATGTTCCAGCGCTTACTGGCCCTGGAGCCCGAGCGCCGCGGCCCAGCCAAGGAGGTGTTCCGCTTCCTCAAGCACGAGCTCACGTCCGAGCTGCGCCGCCGGCCCTCGCACCGCGCGCGCAAGCCCCCCGGGGACCGCCCGCCCGCCGCCGGGCCACTGCGCCTCGAGGCGCCTGGGCCGCTCAAGCGGACGGTGCTGACCGAGAGCGGCAGCGGCTCCCGGCCCGCGCCCCCCGCCGTCGGGTCGGTGCCCTTGCCCGTGCCGGTGCCGGTGCCAGTGCCCGTGCCGGTGCCTGTGCCCGAGCCCGGCCTAGCTCCCCAGGGGCCCCCCGGCCGGACCGACGGCCGCGCGGACAAGAGCAAAGGGCAGGTGGTGCTGGCCACGGCCATCGAGATCTGCGTCTGAGTCGCCTCCGCCGCCCTCGGACCCGGGAGCAGCCCGGGCCCGCCCCGAGCCGGTGCCCGGTGCGGCGGTAGGGAATGGAGCCACCTCGCCGCGGGGCAGGGGGCGCAGCGGTAGACTAGGCAGGACGCGGCCCGGCACCTGGTCCGTCCCCGGCGGGCTGGTGAGGGGGCCACCAAAGACCCCTAGCGCGGCCTGGTGAGCGGGGGCTTGGCCCAGAGGAGCCAAGCCGCACAGACCCGAGAATTCGGAGGCCACCACACAACACACACACACACACACACACACACACACACACACACACACACACACACACACACGCCAGGAGCAAGGGAGCTTTCGGGCCACACTCCCAGACGCCTCCCTGAGCCCTGGAACCCGGACTCGTTGCTCCTGGCCTTCCATACCCCCTGGCAGATCATCCTGCGGTCCCACCCCAGATCCCCTCCTCCTCGCCATCCCATTCTGCCCCCTCCCCACCCTGGGTACAGAAAGGGACTGAAGTGTTGGGCAGAGAGGGGGCTTAAGGCCCCTGGGCACAGGCTGGGATCAGGGCAGTGAGCGAAGGGCAGCTGTGTCCTGCCCTCCCTTCTGGAGGCTGGAGGGGAGAGGCCAAGCCCTTGGAAAATGTAGCAAATGTCTGGATGTCGCATAAGTGCGTGTATGTGCGGGACAGGCCCCGAGAAGCTAGTGACTCCTGCACACCCCCATTGCACAAATGAAATCACAGCCCAGGAGGGAGGGTAGCTTGGCACTGGCTGAGAAATAGAGCTCTCTCCCCGCCCCTCCCCCTAACCACAAGGGATTGTCCTGACAACTTGTGGGGATAGAAGGGCTCACAGGGCAGGGGTCTCAGCTGCCCCCATCCTTAGGGCAGGGGAGTTAGTGTGGAGCCGAGAGCAGGTCCCAGCTCCCCCTGCCAGCCGCACTGTCCCAGGCCCAGGGACCTCTGCCGGGTCCTCCCAGCCCTTGCCACACAGCCTAGACGTAGTAGCCTGGGCTTCCAGCAGGTGGCGAGCTGGTTCGTGCTGGAAATTTCTCCTGGGTTTCTTGGGGTCAAACATGCCAACCTCCAAGACCCCATCCTCACGTCTCCCACTTTTCTGGCGCTGGAGTGTGCAGGGCGTAGGACCTGCATGTGTGGGTGTGAGAATGGGGGCGGTGGACACCAGGGGGCGAGTGTGTGACTAGGTGTGTGTGCACATGTGTAGGGTGCAGACGCATGGGTGCCATCCTTTGCGTTCAGTGACTGTGCGTCCAGACCCCTCACCAGCGGCCCCCCCACCACACCCTGGTCCTCCCAGGCAGCTGTCCCAGGGCGCCCAGGCCTGCCTTGCACCACAGCCCTCAGGAAATCCGGCAAGGAGGCCCCTGCAGGTTGGTTCAGGCCCCCAGGTAGCAAAACAGAGACAACAGCAGCCCCGCCTGACCCCCTGCCCCTCTCTGTGGAGGCCCGGGACCCCCGCAATAAGCACCACATGGGTGAGGCTGTCCCTGTCAGGGTCCCCTGCCAGGGTCCCTCCTGGGGTTCTGGGCCATTTGAGGGGCTCTTTGATGGGCCAGGCCGGCCAGAGTGAACTCCGAGCACTTTCTGGCTGGTGCCCCAACCTCTCCACTCCCCACTCATTCCCACCTTGAAAAAGGGCTATAGGTCCCCTGCCCTGCCCGGGTCCAGTTTACAAACAGTGTGGGGTGGCCCCAGGGCCTGGCCCCACTCTCCCTGCTGTGCCCACTCCTCTCCAGACTCCACCTCCCCAGTGGGTATGGGCCCTCCACATGCCAGGTAAGTAGCAAACCCCCACTCCCTCCAAGGACCAGGTCTCAGAGAAGGCCCTGGTCACTGCCCCCGGCCCACCTGGAGCCCATCGGGGCTGCCTCTCCCAGCCGCGACTTCTCCTTTTGCCTTAGGCCTCGCGACATCCTGATCTCTCCTGCAATAACTAGGAATCGAGATTCCACAGTAGACGTCCCTTGCCGTGCTCGCTCTCTCTCTCGCGCGCGCTCTCTCTCTCCCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCCTCTCTTTCTCTCTCTCCCTCTCTCTGTTAAGATCCTGTTCGGGAGTTTCCCCAGCCGTTGTAGTATCTAGTATGTTAGAGTTGGGAGGGGACCATAGTTATGTAGCCCAGCCCCCTCATTCCCAGAGGCACCCAGAGGGCCAGCCTCCAGCCTGACCCCAGAGCAGAACCGGAACACCAGGTTGGGGCCCTGGTGCTGCCACCTCCTCTGCTGGTCGGGCTGGGACCCTTTGCCCCTTAGGAGAGGTGTTGGTCACAGATGTTTACCTCAGTTTATGTCACTGTCGAAGAAACAAAAAATAATAGCAAAAAATAACACTGTAGACATGAAGACTTAGAAGACAAAAAAAAAAAAATCACACAAAAAATCTCCCTTGTTGCGATTCTTCTGTGAAGGTACAGTGTGTATGTGTGTATGTGTGTATGTGTGTGCGTGTCTCTGTCCCAGACCCTGTGTCCCCCACACTGCCCCCTGTCCTTCGGTGCTTCCCAGAGACCCCTCTGAGCTGGCCTGTGGGGCACGGGAAGCCCCCTGGATGGGAGGCGGGGCCACAGGTCGGCTAGAGGGTCTCCACCAGGCCCACTGAACAGAACCCCACGGCTGCCAGAATGTTCCCTGAGCCCACACTGTGGCCAGTGGGACAGTCCTGGTGGCTGACATCAGCGTCCATGCTTGGCTCAGGGCCTGGGGCGGGGTCCTGGGTAGAGTCCTAGCCCCAGAGCCCCAGCCCCTCATGTCTTGCCGCCCTTCCTCCATGTGTTTGTAAATACTCTGGCATCCTTTGGCCCTGAGAAGGTTTTTAAATGTGTTATTTACTTCTCTAAACATGACGATTGCTATAAAAATAAACAAAAGTTTAGAAAAATGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188322:ENST00000341901:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.324
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(25.5=100)
A:
NA
C2:
PF0006920=Pkinase=PD(65.0=60.6),PF152791=SOBP=WD(100=41.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGACCTGTTTGACATCATCCC
R:
GGTGAGCACGCAGAAGATGAG
Band lengths:
344-1222
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development